scholarly journals Checkpoint immunotherapy of cutaneous squamous cell carcinoma in patients suffering from chronic lymphocytic leukaemia: divergent outcomes in two men treated with PD‐1 inhibitors

2021 ◽  
Vol 36 (S1) ◽  
pp. 41-44
Author(s):  
P. Jansen ◽  
G.C. Lodde ◽  
A. Wetter ◽  
A. Welt ◽  
M. Stuschke ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Chronic Lymphocytic Leukaemia ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymphocytic Leukaemia ◽  
Cutaneous Squamous Cell Carcinoma

Incidence of cutaneous squamous cell carcinoma in a New Zealand population of chronic lymphocytic leukaemia patients

2016 ◽  
Vol 46 (12) ◽  
pp. 1414-1421 ◽  
Author(s):  
B. D. Hock ◽  
N. D. McIntosh ◽  
J. L. McKenzie ◽  
J. F. Pearson ◽  
J. W. Simcock ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
New Zealand ◽  
Chronic Lymphocytic Leukaemia ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymphocytic Leukaemia ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Zealand Population

scholarly journals Rapidly Growing Cutaneous Squamous Cell Carcinoma of the Nose in Chronic Lymphocytic Leukaemia

The Physician ◽  
2020 ◽  
Vol 6 (2) ◽  
Author(s):  
Seth Dhillon
Keyword(s):  
Squamous Cell Carcinoma ◽  
Chronic Lymphocytic Leukaemia ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymphocytic Leukaemia ◽  
Cutaneous Squamous Cell Carcinoma ◽  
National Conference

Poster presented at BAPIO National Conference, London Nov 2019 Peer reviewed by Subarna Chakravorty & Sunil Daga

Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive

2020 ◽  
Vol 134 (5) ◽  
pp. 460-462
Author(s):  
L Li ◽  
L Hamilton ◽  
J Montgomery ◽  
M Stewart
Keyword(s):  
Squamous Cell Carcinoma ◽  
Chronic Lymphocytic Leukaemia ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Hodgkin’S Lymphoma ◽  
Lymphocytic Leukaemia ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma

AbstractBackgroundPatients with non-Hodgkin's lymphoma and chronic lymphocytic leukaemia are at an elevated risk of further malignancy. Head and neck squamous cell carcinoma often presents with cervical lymph node metastasis, and can pose a diagnostic challenge in patients with non-Hodgkin's lymphoma or chronic lymphocytic leukaemia who may have pre-existing palpable neck nodes.MethodsA retrospective case review of a health board was conducted to identify patients with head and neck squamous cell carcinoma with a previous diagnosis of non-Hodgkin's lymphoma or chronic lymphocytic leukaemia.ResultsFour patients with head and neck squamous cell carcinoma that developed after non-Hodgkin's lymphoma or chronic lymphocytic leukaemia were identified. Two patients had a background of non-Hodgkin's lymphoma treated with chemotherapy. The remaining two patients had a background of chronic lymphocytic leukaemia under active surveillance. Three out of the four patients died within 30 months of diagnosis.ConclusionHead and neck squamous cell carcinoma following non-Hodgkin's lymphoma or chronic lymphocytic leukaemia is aggressive. A heightened clinical suspicion is essential to facilitate early diagnosis and treatment of head and neck squamous cell carcinoma in patients with dual pathology.

Aggressive cutaneous squamous cell carcinoma of the head and neck in patients with chronic lymphocytic leukaemia

1996 ◽  
Vol 110 (7) ◽  
pp. 694-695 ◽  
Author(s):  
B. E. J. Hartley ◽  
A. E. Searle ◽  
N. M. Breach ◽  
P. H. Rhys-Evans ◽  
J. M. Henk
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Local Recurrence ◽  
Chronic Lymphocytic Leukaemia ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Lymphocytic Leukaemia ◽  
Management Plan ◽  
High Tendency

AbstractWe describe multiple cutaneous squamous cell carcinomas of the head and neck in five patients with chronic lymphocytic leukaemia (CLL). When associated with CLL, cutaneous squamous cell carcinomata behave in a much more aggressive manner than otherwise expected. Four patients developed local recurrence after primary treatment. All five patients developed lymph node metastases containing squamous cell carcinoma. Three of five patients (60 per cent) had multiple primary lesions.Whereas the increased incidence of second cancers in CLL and notably of skin cancers is documented, little has been written to describe the aggressive behaviour of these tumours. It is important, when treating these patients, to be aware of the high tendency towards local recurrence and lymph node metastasis and to consider an aggressive management plan and careful follow-up.

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