Determination of Physical and Chemical Properties of Oleogels Prepared with Olive Oil and Olive Based Emulsifier

ABSTRACTObjective: Fundamental research in pharmacy and medicine have shown that drugs, which are based on nucleus of the 1,2,4-triazole, have a widerange of biological effects. Derivatives of this heterocyclic system have well-known Ukrainian clinicians and the world scientists due to its antifungal,antidepressant, anticancer, cardio- and hepatoprotective properties. The pharmacological activity of most organic compounds depends on severaldifferent factors, including bioavailability of the substance. Hence, it is very important to consider the results of the synthetic and biological researchesand established dependence of structure on the biological action when scientists model new molecules or improve pharmacological properties of anexisting structure. One of the important social and economic problems of the pharmaceutical industry is the implementation in practice of new drugsthat could compete with expensive imported drugs. In recent times, 1,2,4-triazole-3-thioderivatives take attention of compatriots and scientists offoreign countries who are working on finding bioactive compounds including heterocyclic systems. The structure, physical and chemical properties,pharmacological activities of 1,2,4-triazoles, and their 3-thioderivatives are understudied. Hence, the study of that will be actually and novelty formodern science. The main purpose of our research is synthesis of 3-alkylsulfonyl-5-(chinoline-2-yl, 2-hydroxychinoline-4-yl)-4-R-2,4-dihydro-3N1,2,4-triazoles,studyingof its physicaland chemical properties.Methods: The initial compounds have been synthesized previously using known in literature techniques. Oxidation of the sulfur atom of thesynthesized compounds to the hexavalent condition was carried out adding solution of hydrogen peroxide.Results: The structure of the obtained compounds was determined with the modern physical and chemical analysis methods: Element analysis,infrared-spectrophotometry, and their individuality with thin layer chromatography.Conclusions: Prospect of the further researches is determination of acute toxicity and next studying of pharmacological properties of the synthesizedcompounds.Keywords: 1,2,4-triazoles, Synthesis, Chemical properties, Chinoline.1

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Determination of physical and chemical properties of the aerosol from 1972 to 1982 at a North-Alpine Pure Air Station at 1780 m a.s.l.

Archiv für Meteorologie Geophysik und Bioklimatologie Serie B ◽

10.1007/bf02263345 ◽

1984 ◽

Vol 35 (3) ◽

pp. 179-201 ◽

Cited By ~ 5

Author(s):

R. Reiter ◽

W. Camuth ◽

R. Sladkovic

Keyword(s):

Chemical Properties ◽

Physical And Chemical Properties ◽

Physical And Chemical ◽

And Chemical Properties

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Universal Approach for Determination of Physical and Chemical Properties of Water by Near-IR Spectroscopy

Applied Spectroscopy ◽

10.1366/0003702934334589 ◽

1993 ◽

Vol 47 (10) ◽

pp. 1720-1727 ◽

Cited By ~ 32

Author(s):

Jie Lin ◽

Chris W. Brown

Keyword(s):

Ir Spectroscopy ◽

Chemical Properties ◽

Fiber Optic Sensor ◽

Universal Method ◽

Physical And Chemical Properties ◽

Near Ir ◽

Universal Approach ◽

Physical And Chemical ◽

And Chemical Properties

Near-IR spectroscopy has been investigated as a universal approach for determination of physical and chemical properties of water and their functions of temperature. Principal component regression and multilinear regression models were used to correlate the spectra with the properties of water at temperatures between 5 and 65°C. Fifteen properties of water were investigated including density, refractive index, dielectric constant, relative viscosity, surface tension, vapor pressure, sound velocity, isothermal compressibility, thermal expansivity, thermal capacity, thermal conductivity, enthalpy, free energy, entropy, and ionization constant. Very good correlations were found between the near-IR predicted values of all the properties and those obtained by the traditional methods. This investigation demonstrates that these fifteen properties of water can be simultaneously determined simply by measuring a set of near-IR spectra of water, and, thus, near-IR spectroscopy can be used as a universal method for the determinations of physical and chemical properties of water. Remote sensing of the properties can be performed with the use of a fiber-optic sensor.

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Isolation and determination of some physical and chemical properties of polysaccharide from black elderberry flowers

Herald of Tver State University. Series: Biology and Ecology ◽

10.26456/vtbio163 ◽

2020 ◽

pp. 95-101

Author(s):

Игорь Анатольевич Сычев ◽

Татьяна Викторовна Алимкина

Keyword(s):

Medicinal Plant ◽

Quantitative Determination ◽

Raw Materials ◽

Chemical Properties ◽

Physical And Chemical Properties ◽

Plant Raw Materials ◽

Physical And Chemical ◽

And Chemical Properties

Предложенный метод количественного определения восстанавливающих моносахаридов в полисахариде позволяет проводить стандартизацию лекарственного растительного сырья цветков бузины черной. На способ стандартизации лекарственного растительного сырья цветков бузины черной по содержанию восстанавливающих моносахаридов в полисахариде оформлено рационализаторское предложение № 1373 от 29.02.2016 г. РязГМУ. The proposed method for the quantitative determination of reducing monosaccharides in a polysaccharide makes it possible to standardize medicinal plant raw materials of black elderberry flowers. On the method of standardization of medicinal plant raw materials of black elderberry flowers in terms of the content of reducing monosaccharides in the polysaccharide, a rationalization proposal No. 1373 dated February 29, 2016 RyazSMU was issued.

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