Magnetic resonance elastography increases usefulness and safety of non‐invasive screening for esophageal varices

2018 ◽  
Vol 33 (12) ◽  
pp. 2022-2028 ◽  
Author(s):  
Nobuaki Matsui ◽  
Kento Imajo ◽  
Masato Yoneda ◽  
Takaomi Kessoku ◽  
Yasushi Honda ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Esophageal Varices ◽  
Magnetic Resonance Elastography ◽  
Non Invasive

Non-invasive assessment of liver fibrosis using magnetic resonance elastography in liver transplant recipients with hepatitis C

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Sergio Crespo ◽  
Mellena Bridges ◽  
Raouf Nakhleh ◽  
Andre McPhail ◽  
Surakit Pungpapong ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Magnetic Resonance ◽  
Liver Fibrosis ◽  
Liver Transplant ◽  
Magnetic Resonance Elastography ◽  
Transplant Recipients ◽  
Non Invasive ◽  
Liver Transplant Recipients

scholarly journals Non-invasive characterization of intracranial tumors by magnetic resonance elastography

2013 ◽  
Vol 15 (8) ◽  
pp. 085024 ◽  
Author(s):  
M Simon ◽  
J Guo ◽  
S Papazoglou ◽  
H Scholand-Engler ◽  
C Erdmann ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Elastography ◽  
Intracranial Tumors ◽  
Non Invasive

scholarly journals Preliminary experience with 3T magnetic resonance elastography imaging of the liver

2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Anagha Joshi ◽  
Mridula M. Muthe ◽  
Vikrant Firke ◽  
Harshal Badgujar
Keyword(s):  
Magnetic Resonance ◽  
Hepatic Fibrosis ◽  
Liver Stiffness ◽  
Stage Iv ◽  
Normal Liver ◽  
Magnetic Resonance Elastography ◽  
Invasive Technique ◽  
Non Invasive ◽  
The Waves ◽  
Identification And Quantification

Background: Magnetic resonance elastography (MRE) is a promising non-invasive technique for the identification and quantification of hepatic fibrosis. This manuscript describes our early experience with MRE for the assessment of the presence and staging of liver fibrosis on a 3T magnetic resonance imaging (MRI) system.Objectives: The purpose of this study was to describe the MRE physics, procedure, interpretation and drawbacks, along with a few recommendations as per our experience.Method: Magnetic resonance elastography was performed on 85 patients with a 3T MRI and the images were analysed both qualitatively and quantitatively. Liver stiffness was assessed by drawing freehand geographic regions of interest on the elastograms to cover the maximum portion of the hepatic parenchyma within the 95% confidence maps on each slice. Correlation with histopathology was performed whenever available.Results: Of the 80 patients who met the inclusion criteria, 41 patients displayed a normal liver stiffness measurement (LSM) and 39 patients had a raised LSM. In the patients who had a raised LSM, 14 patients had Stage I–II fibrosis, 8 patients had Stage II–III fibrosis, 6 patients had Stage III–IV fibrosis, 4 patients had Stage IV fibrosis or cirrhosis and 7 patients had non-alcoholic steatohepatitis. The mean thickness of the waves increased with increasing stages of fibrosis. The waves became gradually darker medially in patients with normal LSM as compared to the patients with raised LSM. Histopathology with METAVIR scoring was available in 46 patients, which agreed with the MRE findings in all except two patients.Conclusion: Magnetic resonance elastography is a suitable non-invasive modality for the identification and quantification of hepatic fibrosis.

Magnetic resonance elastography: Non-invasive mapping of tissue elasticity

2001 ◽  
Vol 5 (4) ◽  
pp. 237-254 ◽  
Author(s):  
A. Manduca ◽  
T.E. Oliphant ◽  
M.A. Dresner ◽  
J.L. Mahowald ◽  
S.A. Kruse ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Elastography ◽  
Tissue Elasticity ◽  
Non Invasive

Initial In-Vivo Results Considering Rayleigh Damping in Magnetic Resonance Elastography

2009 ◽  
Author(s):  
D. Viviers ◽  
E. E. W. Van Houten ◽  
M. D. J. McGarry ◽  
J. B. Weaver ◽  
K. D. Paulsen
Keyword(s):  
Magnetic Resonance ◽  
Soft Tissue ◽  
Shear Modulus ◽  
Material Properties ◽  
Magnetic Resonance Elastography ◽  
Imaginary Component ◽  
Non Invasive ◽  
Rayleigh Damping ◽  
Time Harmonic ◽  
Complex Valued

Dispersive material properties provide valuable metrics for characterizing the nature of soft tissue lesions. Magnetic Resonance Elastography (MRE) targets non-invasive breast cancer diagnosis and is capable of imaging the damping properties of soft tissue. 3D time-harmonic displacement data obtained via MRI is used to drive a reconstruction algorithm capable of deducing the distribution of mechanical properties in the tissue. To make the most of this diagnostic capability, characterization of the damping behavior of tissue is made more sophisticated by the use of a Rayleigh damping model. To date, time-harmonic motion attenuation in tissue as found in dynamic MRE has been characterized by a single parameter model that takes the form of an imaginary component of a complex valued shear modulus. A more generalized damping formulation for the time-harmonic case, known commonly as Rayleigh or proportional damping, includes an additional parameter that takes the form of an imaginary component of a complex valued density. The effects of these two different damping mechanisms can be shown to be independent across homogeneous distributions and mischaracterization of the damping structure can be shown to lead to artifacts in the reconstructed attenuation profile. We have implemented a Rayleigh damping reconstruction method for MRE and measured the dispersive properties of actual patient data sets with impressive results. Reconstructions show a close match with varying tissue structure. The reconstructed values for real shear modulus and overall damping levels are in reasonable agreement with values established in the literature or measured by mechanical testing, and in the case of malignant lesions, show good correspondence with contrast enhanced MRI. There is significant medical potential for an algorithm that can accurately reconstruct soft tissue material properties through non invasive MRI scans. Imaging methods that help identify invasive regions through reconstruction of dispersive soft tissue properties could be applied to pathologies in the brain, lung, liver and kidney as well.

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