Topical growth factors and home‐based microneedling for facial skin rejuvenation

Author(s):  
Daniel J. Quinlan ◽  
Ali M. Ghanem ◽  
Haidar Hassan
Author(s):  
Barbara Hersant ◽  
Mounia SidAhmed-Mezi ◽  
Celine Aboud ◽  
Jeremy Niddam ◽  
Samuel Levy ◽  
...  

Abstract Background Many therapeutic options are currently available for facial skin rejuvenation, but little evidence exists about the efficacy of combining such procedures. Objectives To assess and investigate the synergic effect of HA and a-PRP injections on facial skin rejuvenation. Methods For this randomized controlled prospective study, 93 eligible patients were enrolled and randomized into three intervention groups to undergo a series of three treatments sessions with either a-PRP, HA or Cellular Matrix-BCT-HA (PRP-HA) injected on facial cheeks. Results A total of 93 patients were included. Treatment with Cellular Matrix BCT-HA led to a very significant improvement in the overall facial appearance compared to groups treated with a-PRP and HA alone (p<0.0001). Participants treated with Cellular Matrix showed a 20%, 24% and 17% increase in FACE-Q score at 1 month, 3 months and 6 months post-treatment, respectively. For the HA group, the improvement of FACE-Q score was 12%, 11% and 6% at 1, 3- and 6-months post-treatment, respectively, while the a-PRP group showed a 9% improvement in FACE-Q score at 1 month and 11% and 8% improvement at 3- and 6-months post-treatment, respectively.Biophysical measurements showed significantly improved skin elasticity for the group Cellular BCT-HA compared to a-PRP and HA alone. No serious adverse events were reported. Conclusions Combining a-PRP and HA seems to be a promising treatment for facial rejuvenation with a very significant improvement in facial appearance and skin elasticity compared to a-PRP or HA alone.


Medicines ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 18
Author(s):  
Hiroshi Kuge ◽  
Hidetoshi Mori ◽  
Tim Hideaki Tanaka ◽  
Ryouta Tsuji

Background: In recent years, cosmetic acupuncture has gained popularity among individuals interested in improving their facial appearance. We have created an original facial check sheet (FCS) to obtain cosmetic acupuncture patients’ perspectives on treatment outcomes. This study examined the reliability and validity of FCS. Methods: We conducted an Internet survey on the appearance of the facial region among Japanese women. A reliability analysis was performed between each item of FCS. A multiple comparison procedure was used to determine the relationship between the age group, the FCS score, and the number of terms used in the open-ended question. Results: The most frequently stated concern was blotchiness and hyperpigmented spots (47.2%, n = 67). The FCS items showed reliability (Cronbach α = 0.871). The number of extracted terms and the FCS score showed a moderate correlation (r = 0.407; p < 0.001). There was a significant relationship between age and FCS score (p = 0.005, r2 = 0.255), which indicated that the FCS score increases with aging. Conclusions: The FCS can be used as a practical tool to evaluate facial appearances and assess satisfaction levels of patients who underwent cosmetic acupuncture or other facial skin rejuvenation procedures.


2020 ◽  
Vol 46 (12) ◽  
pp. e112-e117 ◽  
Author(s):  
Pier Paolo Rovatti ◽  
Giovanni Pellacani ◽  
Stefania Guida

2016 ◽  
Vol 49 (1) ◽  
pp. 78-83 ◽  
Author(s):  
Barbara Hersant ◽  
Mounia SidAhmed-Mezi ◽  
Adrien Chossat ◽  
Jean Paul Meningaud

2018 ◽  
Vol 1 (1) ◽  
pp. 9-23
Author(s):  
Teresa Matthews‑Brzozowska ◽  
Maja Matthews‑Kozanecka ◽  
Aleksandra Krzyżanowska‑Lula ◽  
Weronika Kawałkiewicz ◽  
Dorota Hojan‑Jezierska

In facial skin revitalization it is important to use preventive measures and introduce minimally invasive treatments as soon as the first signs of ageing appear. Such treatments can include the administration of stem cells and concentrated growth factors (CGF Harmony). This procedure was used in the case presented in this paper. Its effects were assessed on the basis of medical photographic documentation obtained using the FotoMedicus system, and instrumental examination of skin parameters, phototype, hydration and redness by means of a Cutometer Dual MPA 580. CGF Harmony was applied three times, and after the second and third application an improvement in the majority of the assessed parameters was observed. However, it cannot be unequivocally demonstrated that three CGF Harmony applications are sufficient for 40+ patients; it may be necessary to monitor skin condition over a longer period of time and introduce combined treatments in the area of facial aesthetic medicine.


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