scholarly journals RELATIONSHIP BETWEEN NEONATAL MRI, CLINICAL ASSESSMENT SCORES AND NEURODEVELOPMENTAL OUTCOMES AT 2 YEARS CORRECTED AGE IN VERY PRETERM BORN INFANTS

2019 ◽  
Vol 55 (S1) ◽  
pp. 19-20

Author(s):  
Anne R Synnes ◽  
Julie Petrie ◽  
Ruth E Grunau ◽  
Paige Church ◽  
Edmond Kelly ◽  
...  

ObjectiveTo examine whether the family integrated care (FICare) programme, a multifaceted approach which enables parents to be engaged as primary caregivers in the neonatal intensive care unit, impacts infant neurodevelopment and growth at 18 months’ corrected age.Design/MethodsProspective cohort study of infants born <29 weeks’ gestational age (GA) who participated in the FICare cluster randomised control trial (cRCT) and were assessed in the Canadian Neonatal Follow-Up Network (CNFUN). The primary outcome measure, Cognitive or Language composite score <85 on the Bayley-III, was compared between FICare exposed and routine care children using logistic regression, adjusted for potential confounders and employing generalised estimation equations to account for clustering of infants within sites.ResultsOf 756 infants <29 weeks’ GA in the FICare cRCT, 505 were enrolled in CNFUN and 455 were assessed (238 FICare, 217 control). Compared with controls, FICare infants had significantly higher incidence of intraventricular haemorrhage (IVH) (19.5% vs 11.7%, p=0.024) and higher proportion of employed mothers (76.6% vs 73.6%, p=0.043). There was no significant difference in the odds of the primary outcome (adjusted OR: 0.92 (0.59 to 1.42) FiCare vs Control) on multivariable analyses adjusted for GA, IVH and maternal employment. However, Bayley-III Motor scores (adjusted difference in mean (95% CI) 3.87 (1.22 to 6.53) and body mass index 0.67 (0.36 to 0.99) were higher in the FICare group.ConclusionsVery preterm infants exposed to FICare had no significant difference in incidence of cognitive or language delay but had better motor development.Trial registration numberParticipants in this cohort study were previously enrolled in a registered trial: NCT01852695



PEDIATRICS ◽  
2021 ◽  
Vol 148 (3) ◽  
pp. e2020049572
Author(s):  
Sahar Salavati ◽  
Arend F. Bos ◽  
Lex W. Doyle ◽  
Peter J. Anderson ◽  
Alicia J. Spittle


2018 ◽  
Vol 131 (8) ◽  
pp. 920-926 ◽  
Author(s):  
Xue-Hua Zhang ◽  
Shi-Jun Qiu ◽  
Wen-Juan Chen ◽  
Xi-Rong Gao ◽  
Ya Li ◽  
...  


2019 ◽  
Vol 129 ◽  
pp. 45-51 ◽  
Author(s):  
Regula Everts ◽  
Corina G. Schöne ◽  
Ines Mürner-Lavanchy ◽  
Maja Steinlin


2019 ◽  
Vol 109 (7) ◽  
pp. 1499-1499
Author(s):  
Despina D. Briana ◽  
Ariadne Malamitsi‐Puchner


2019 ◽  
Vol 2 (5) ◽  
pp. e192914 ◽  
Author(s):  
Isabel Benavente-Fernández ◽  
Anne Synnes ◽  
Ruth E. Grunau ◽  
Vann Chau ◽  
Chantel Ramraj ◽  
...  


2020 ◽  
Vol 25 (3) ◽  
pp. 101109 ◽  
Author(s):  
Héloïse Torchin ◽  
Andreï S. Morgan ◽  
Pierre-Yves Ancel


NeuroImage ◽  
2015 ◽  
Vol 111 ◽  
pp. 360-368 ◽  
Author(s):  
Julia M. Young ◽  
Tamara L. Powell ◽  
Benjamin R. Morgan ◽  
Dallas Card ◽  
Wayne Lee ◽  
...  


Sign in / Sign up

Export Citation Format

Share Document