scholarly journals A ten gene-containing genomic island determines flagellin glycosylation: implication for its regulatory role in motility and virulence ofXanthomonas oryzaepv.oryzae

2017 ◽  
Vol 19 (3) ◽  
pp. 579-592 ◽  
Author(s):  
Chao Yu ◽  
Huamin Chen ◽  
Fang Tian ◽  
Fenghuan Yang ◽  
Xiaochen Yuan ◽  
...  
Keyword(s):  
Genomic Island ◽  
Regulatory Role ◽  
Flagellin Glycosylation

scholarly journals An Aeromonas caviae Genomic Island Is Required for both O-Antigen Lipopolysaccharide Biosynthesis and Flagellin Glycosylation

2009 ◽  
Vol 191 (8) ◽  
pp. 2851-2863 ◽  
Author(s):  
S. Mohammed B. Tabei ◽  
Paul G. Hitchen ◽  
Michaela J. Day-Williams ◽  
Susana Merino ◽  
Richard Vart ◽  
...  
Keyword(s):  
Biosynthetic Pathway ◽  
Wild Type Strain ◽  
Genomic Island ◽  
Insertion Element ◽  
Acid Biosynthesis ◽  
O Antigen ◽  
Aeromonas Caviae ◽  
Lipopolysaccharide Biosynthesis ◽  
Pseudaminic Acid ◽  
Flagellin Glycosylation

ABSTRACT Aeromonas caviae Sch3N possesses a small genomic island that is involved in both flagellin glycosylation and lipopolysaccharide (LPS) O-antigen biosynthesis. This island appears to have been laterally acquired as it is flanked by insertion element-like sequences and has a much lower G+C content than the average aeromonad G+C content. Most of the gene products encoded by the island are orthologues of proteins that have been shown to be involved in pseudaminic acid biosynthesis and flagellin glycosylation in both Campylobacter jejuni and Helicobacter pylori. Two of the genes, lst and lsg, are LPS specific as mutation of them results in the loss of only a band for the LPS O-antigen. Lsg encodes a putative Wzx flippase, and mutation of Lsg affects only LPS; this finding supports the notion that flagellin glycosylation occurs within the cell before the flagellins are exported and assembled and not at the surface once the sugar has been exported. The proteins encoded by flmA, flmB, neuA, flmD, and neuB are thought to make up a pseudaminic acid biosynthetic pathway, and mutation of any of these genes resulted in the loss of motility, flagellar expression, and a band for the LPS O-antigen. Furthermore, pseudaminic acid was shown to be present on both flagellin subunits that make up the polar flagellum filament, to be present in the LPS O-antigen of the A. caviae wild-type strain, and to be absent from the A. caviae flmD mutant strain.

scholarly journals A genomic island in Pseudomonas aeruginosa carries the determinants of flagellin glycosylation

2001 ◽  
Vol 98 (16) ◽  
pp. 9342-9347 ◽  
Author(s):  
S. K. Arora ◽  
M. Bangera ◽  
S. Lory ◽  
R. Ramphal
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Genomic Island ◽  
Flagellin Glycosylation

Regulatory role of PhoP

Nature India ◽  
2009 ◽  
Keyword(s):  
Regulatory Role

Regulatory role of resistin on ovarian function

2014 ◽  
Author(s):  
Agnieszka Rak-Mardyla ◽  
Anna Wrobel ◽  
Eliza Drwal ◽  
Ewa Gregoraszczuk
Keyword(s):  
Ovarian Function ◽  
Regulatory Role
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