De‐indexed estimated glomerular filtration rates: A simple step towards improving accuracy of drug dosing of renally excreted medications in moderate to severe obesity

Nephrology ◽  
2019 ◽  
Vol 25 (1) ◽  
pp. 29-31 ◽  
Author(s):  
Caitlyn Vlasschaert ◽  
Stephane Thibodeau ◽  
Malvinder S Parmar
Keyword(s):  
Glomerular Filtration ◽  
Severe Obesity ◽  
Drug Dosing ◽  
Simple Step ◽  
Improving Accuracy ◽  
Estimated Glomerular Filtration Rates

Drugs and the kidney

2010 ◽  
pp. 4174-4188
Author(s):  
Aine Burns ◽  
Caroline Ashley
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Critical Role ◽  
The Body ◽  
Medical Practitioners ◽  
Drug Dosing ◽  
Estimated Glomerular Filtration Rates ◽  
Careful Thought ◽  
Reduced Renal Function

The kidney plays a critical role in the elimination of many drugs from the body, hence consideration should be given to a patient’s renal function whenever any drug is prescribed. Much kidney disease is unrecognized, but the widespread reporting of estimated glomerular filtration rates (eGFR) has brought greater awareness of the prevalence of chronic kidney disease (CKD) and thereby encouraged medical practitioners to take account of reduced renal function when prescribing. CKD is very often one of many coexisting comorbid conditions, especially in elderly patients, when particularly careful thought must be given to appropriate drug dosing and the possibility of drug interactions....

Estimated Glomerular Filtration Rate Bias in Participants with Severe Obesity Regardless of Deindexation

Obesity ◽  
2019 ◽  
Vol 27 (12) ◽  
pp. 2011-2017 ◽  
Author(s):  
Fitsum Guebre‐Egziabher ◽  
Charlotte Brunelle ◽  
Jouve Thomas ◽  
Caroline C. Pelletier ◽  
Gabrielle Normand ◽  
...  
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Severe Obesity
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