scholarly journals Gut microbiome dysbiosis and increased intestinal permeability in children with islet autoimmunity and type 1 diabetes: A prospective cohort study

2019 ◽  
Author(s):  
Jessica E. Harbison ◽  
Alexandra J. Roth‐Schulze ◽  
Lynne C. Giles ◽  
Cuong D. Tran ◽  
Katrina M. Ngui ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cohort Study ◽  
Intestinal Permeability ◽  
Prospective Cohort Study ◽  
Gut Microbiome ◽  
Prospective Cohort ◽  
Islet Autoimmunity

scholarly journals Association between maternal gluten intake and type 1 diabetes in offspring: national prospective cohort study in Denmark

BMJ ◽  
2018 ◽  
pp. k3547 ◽  
Author(s):  
Julie C Antvorskov ◽  
Thorhallur I Halldorsson ◽  
Knud Josefsen ◽  
Jannet Svensson ◽  
Charlotta Granström ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cohort Study ◽  
Confidence Interval ◽  
Prospective Cohort Study ◽  
Food Frequency Questionnaire ◽  
Prospective Cohort ◽  
Hazard Ratio ◽  
Adjusted Hazard Ratio ◽  
Food Frequency

Abstract Objective To examine the association between prenatal gluten exposure and offspring risk of type 1 diabetes in humans. Design National prospective cohort study. Setting National health information registries in Denmark. Participants Pregnant Danish women enrolled into the Danish National Birth Cohort, between January 1996 and October 2002, Main outcome measures Maternal gluten intake, based on maternal consumption of gluten containing foods, was reported in a 360 item food frequency questionnaire at week 25 of pregnancy. Information on type 1 diabetes occurrence in the participants’ children, from 1 January 1996 to 31 May 2016, were obtained through registry linkage to the Danish Registry of Childhood and Adolescent Diabetes. Results The study comprised 101 042 pregnancies in 91 745 women, of whom 70 188 filled out the food frequency questionnaire. After correcting for multiple pregnancies, pregnancies ending in abortions, stillbirths, lack of information regarding the pregnancy, and pregnancies with implausibly high or low energy intake, 67 565 pregnancies (63 529 women) were included. The average gluten intake was 13.0 g/day, ranging from less than 7 g/day to more than 20 g/day. The incidence of type 1 diabetes among children in the cohort was 0.37% (n=247) with a mean follow-up period of 15.6 years (standard deviation 1.4). Risk of type 1 diabetes in offspring increased proportionally with maternal gluten intake during pregnancy (adjusted hazard ratio 1.31 (95% confidence interval 1.001 to 1.72) per 10 g/day increase of gluten). Women with the highest gluten intake versus those with the lowest gluten intake (≥20 v <7 g/day) had double the risk of type 1 diabetes development in their offspring (adjusted hazard ratio 2.00 (95% confidence interval 1.02 to 4.00)). Conclusions High gluten intake by mothers during pregnancy could increase the risk of their children developing type 1 diabetes. However, confirmation of these findings are warranted, preferably in an intervention setting.

scholarly journals Subarachnoid Hemorrhage in Type 1 Diabetes: A prospective cohort study of 4,083 patients with diabetes

Diabetes Care ◽  
2013 ◽  
Vol 36 (11) ◽  
pp. 3754-3758 ◽  
Author(s):  
M. Korja ◽  
L. M. Thorn ◽  
S. Hagg ◽  
J. Putaala ◽  
R. Liebkind ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cohort Study ◽  
Subarachnoid Hemorrhage ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Patients With Diabetes

scholarly journals Diabetes Data Management System to Improve Glycemic Control in People With Type 1 Diabetes: Prospective Cohort Study

2017 ◽  
Vol 5 (11) ◽  
pp. e170 ◽  
Author(s):  
Concetta Irace ◽  
Matthias Axel Schweitzer ◽  
Cesare Tripolino ◽  
Faustina Barbara Scavelli ◽  
Agostino Gnasso
Keyword(s):  
Type 1 Diabetes ◽  
Cohort Study ◽  
Glycemic Control ◽  
Data Management ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Management System ◽  
Data Management System

Gut Microbiome Dysbiosis and Increased Intestinal Permeability in Australian Children with Islet Autoimmunity and Type 1 Diabetes

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 230-OR ◽  
Author(s):  
JESSICA E. HARBISON ◽  
ALEXANDRA J. ROTH-SCHULZE ◽  
SIMON C. BARRY ◽  
CUONG D. TRAN ◽  
KATRINA NGUI ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Intestinal Permeability ◽  
Gut Microbiome ◽  
Islet Autoimmunity

scholarly journals Maternal Antibiotic Use During Pregnancy and Type 1 Diabetes in Children—A National Prospective Cohort Study

Diabetes Care ◽  
2018 ◽  
Vol 41 (12) ◽  
pp. e155-e157 ◽  
Author(s):  
Martin Haupt-Jørgensen ◽  
Camilla S. Morgen ◽  
Tine Jess ◽  
Karsten Buschard ◽  
Knud Josefsen ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Antibiotic Use

Predictors of traffic events due to hypoglycemia in adults with type 1 diabetes: a Brazilian prospective cohort study

2021 ◽  
pp. 108954
Author(s):  
Rafaela Fenalti Salla ◽  
Julia de David ◽  
Larissa Schneider ◽  
Balduino Tschiedel ◽  
Gabriela H. Teló ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort
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