scholarly journals P6‐13: Clinical impact of low body mass index in patients with Mycobacterium avium complex pulmonary disease

Respirology ◽  
2021 ◽  
Vol 26 (S3) ◽  
pp. 230-230
2018 ◽  
Vol 29 (1) ◽  
pp. 105-112 ◽  
Author(s):  
Wataru Hirose ◽  
Masayoshi Harigai ◽  
Takashi Uchiyama ◽  
Kenji Itoh ◽  
Toshiaki Ishizuka ◽  
...  

2021 ◽  
Vol 10 (8) ◽  
pp. 1576
Author(s):  
Hironori Sadamatsu ◽  
Koichiro Takahashi ◽  
Hiroki Tashiro ◽  
Koji Kusaba ◽  
Tetsuro Haraguchi ◽  
...  

Background: A low body mass index (BMI) has been reported to be a poor prognostic factor for Mycobacterium avium complex pulmonary disease (MAC-PD). The purpose of this study was to clarify the clinical features of MAC-PD in cases with a low BMI. Methods: This retrospective study analyzed the data of patients diagnosed with MAC-PD at Saga University Hospital between 2008 and 2019. The analyzed patient characteristics included age, gender, BMI, symptoms, laboratory data, chest computed tomography findings, and the treatment courses. We also investigated the factors associated with successful treatment. Results: In total, 144 patients were included in this study. The low-BMI group (BMI < 18.5 kg/m2) had a higher incidence of sputum, Mycobacterium intracellurare infection, and cavitary lesions, in addition to lower blood lymphocyte counts, higher neutrophil–lymphocyte ratios, and a lower prognostic nutritional index (PNI) when compared to the preserved-BMI group (BMI ≥ 18.5 kg/m2). Sixty-six of the 144 patients (45.8%) received treatment. Hemosputum, acid-fast bacillus sputum smear positivity, low lymphocyte counts, a low PNI, and unsuccessful treatment (48.5% vs. 24.2%, p < 0.05) were found to be associated with a low BMI. Conclusions: A low BMI is associated with cavitary lesions, malnutrition, and unsuccessful treatment in MAC-PD.


Respiration ◽  
2006 ◽  
Vol 73 (6) ◽  
pp. 757-761 ◽  
Author(s):  
Roberto A. Rabinovich ◽  
Esther Ardite ◽  
Ana Maria Mayer ◽  
Maite Figueras Polo ◽  
Jordi Vilaró ◽  
...  

2021 ◽  
Vol 19 (1) ◽  
pp. 135-139
Author(s):  
Ritamvara Oli ◽  
Jai Krishna Mishra ◽  
Govind Narayan Srivastava ◽  
Saurabh Mishra

Background: Various studies have shown that low body mass index co-relates with the severity of Chronic obstructive pulmonary disease. The reduced body mass index in these patients is thought to be due to nutritional abnormality and raised circulating inflammatory markers. The study is aimed to find the association of body mass index with respiratory failure in patient with chronic obstructive pulmunory disease.Methods: 142 patients who attended emergency /out-patient-department in Sir Sundarlal Hospital from August 2018 to July 2020 were enrolled for the study. 81 patients in one group had chronic obstructive pulmonary disease exacerbation with Type II respiratory failure. Among this group low and normal body mass index subgroup was categorized.61 patients in another group had chronic obstructive pulmonary disease. Non-invasive ventilation was applied to case group. Categorization of body mass index was done <18.5(Low BMI) and 18.5-24.9 (Normal BMI ). Results: The mean age of the study group was (63.53±9.021). There was a significant difference in the body mass index between the groups ( p=<0.001,t=15.40). Severity of respiratory failure was compared using ph and pco2 in the between the groups which showed no significant difference (p=1,chi square 0.000), (p=0.40,chi square=0.72) however it did affect the outcome.Conclusions: Our study shows that overall respiratory failure was common in low body mass index cases compared to Control. Nevertheless there was no difference among severity of respiratory failure among low and normal body mass index subgroups and however it did affect the outcome.Keywords: Brain natriuretic peptide; chronic obstructive pulmonary diseases; non-invasive ventilation


2016 ◽  
Vol 20 (2) ◽  
pp. 64-71
Author(s):  
Funda Yıldırım Baş ◽  
Bahriye Arslan ◽  
Yasemin Türker

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