scholarly journals High‐frequency (20 MHz) high‐intensity focused ultrasound: New Treatment of actinic keratosis, basal cell carcinoma, and Kaposi sarcoma. An open‐label exploratory study

2020 ◽  
Vol 26 (6) ◽  
pp. 824-831 ◽  
Author(s):  
Jørgen Serup ◽  
Torsten Bove ◽  
Tomasz Zawada ◽  
Alexander Jessen ◽  
Mattia Poli
Keyword(s):  
Basal Cell Carcinoma ◽  
Actinic Keratosis ◽  
High Intensity ◽  
High Frequency ◽  
Exploratory Study ◽  
Focused Ultrasound ◽  
Kaposi Sarcoma ◽  
High Intensity Focused Ultrasound ◽  
Open Label ◽  
New Treatment

Efficacy Assessment of the High-Frequency High-Intensity Focused Ultrasound as a New Treatment for Actinic Keratosis

Dermatology ◽  
2021 ◽  
pp. 1-6
Author(s):  
S. Morteza Seyed Jafari ◽  
Simone Cazzaniga ◽  
Simon Bossart ◽  
Laurence Feldmeyer ◽  
Lorenzo Pelloni ◽  
...  
Keyword(s):  
Actinic Keratosis ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Cutaneous Lesion ◽  
High Intensity Focused Ultrasound ◽  
Safe Alternative ◽  
Risk Of Progression ◽  
Late Adverse Effects ◽  
Efficacy Assessment ◽  
New Treatment

<b><i>Background:</i></b> Actinic keratosis (AK) is the most common precancerous cutaneous lesion, with risk of progression to cutaneous squamous cell carcinoma. In the current study, we evaluated the efficacy of 20-MHz high-intensity focused ultrasound (HIFU), as a new treatment modality for AK. <b><i>Materials and Methods:</i></b> Patients with AK lesions (grades I–III) treated with HIFU were included in the study. The clinical assessment was performed 3 months after therapy. <b><i>Results:</i></b> Twenty-one patients (14 men, 7 women) with 108 AK lesions (grades I–III) were included in the current study. Ages ranged from 62 to 85 years (mean 72.6 years). Clinically complete resolution of the actinic damage in the treated area was detected in 72.2% of lesions. Furthermore, 28 lesions (26%) showed a reduction of the AK grade, or partial response, after the therapy. Most of the patients experienced annoying but short pain during the procedure. However, late adverse effects of the therapy, such as hypopigmentation, hyperpigmentation and erythema were reported only in a small portion of the lesions. <b><i>Conclusions:</i></b> 20-MHz HIFU could be an effective and safe alternative treatment for AK.

scholarly journals An Exploratory Study of Dose Escalation vs Standard Focal High-Intensity Focused Ultrasound for Treating Nonmetastatic Prostate Cancer

2020 ◽  
Vol 34 (6) ◽  
pp. 641-646
Author(s):  
Philipp M. Huber ◽  
Naveed Afzal ◽  
Manit Arya ◽  
Silvan Boxler ◽  
Tim Dudderidge ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dose Escalation ◽  
High Intensity ◽  
Exploratory Study ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound

scholarly journals High-intensity focused ultrasound for treatment of recurrent uterine leiomyosarcoma: a case report and literature review

2020 ◽  
Vol 48 (10) ◽  
pp. 030006052094210
Author(s):  
Junyan Li ◽  
Xuejun Chen ◽  
Xiaoye Hu
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Treatment Strategy ◽  
High Intensity ◽  
Poor Prognosis ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
High Recurrence Rate ◽  
Uterine Leiomyosarcoma ◽  
New Treatment

Uterine leiomyosarcoma has the characteristics of high malignancy, a poor prognosis, and a high recurrence rate. Surgery is the main treatment option, supplemented by chemotherapy and radiotherapy. We report on a patient with recurrent uterine leiomyosarcoma who was treated with high-intensity focused ultrasound combined with chemotherapy. Tumor growth was controlled and the patient’s survival time was prolonged. High-intensity focused ultrasound combined with chemotherapy may thus provide a new treatment strategy for patients with recurrent and surgically difficult uterine leiomyosarcoma.

High‐frequency (20  MH z) high‐intensity focused ultrasound system for dermal intervention: A 12‐week local tolerance study in minipigs

2019 ◽  
Vol 26 (2) ◽  
pp. 241-254 ◽  
Author(s):  
Susi Soegaard ◽  
Vibeke Aarup ◽  
Jørgen Serup ◽  
Torsten Bove ◽  
Tomasz Zawada ◽  
...  
Keyword(s):  
High Intensity ◽  
High Frequency ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Local Tolerance ◽  
Tolerance Study ◽  
Ultrasound System
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