Validation of the elastic angle for quantitative and visible evaluation of skin elasticity in vivo

Background: The Cutometer MPA 580® (Courage and Khazaka, Germany) is a well-established instrument for the accurate and reproducible measurement of the biomechanical properties of the skin. The purpose of this study was to assess the effect of 4 formulations containing 2.5% and 5.0% of α-lipoic acid and ascorbic palmitate or butylhydroxytoluene on skin elasticity and firmness and to assess the equivalence between alternative parameters (Q0, Q1 and Q3) and the traditional parameters R0, R2, R5, R6, all determined with the same cutometer. Methods: Measure of in vivo firmness and elasticity of the skin was performed using R and Q parameters measured in the same device. Results: Different statistical analysis were applied to the results obtained from the parameters (Q0, Q1 and Q3) and the traditional parameters R0, R2, of the in vivo measurements after the application of the four formulations during 28 days. A correlation between both types of measurements was demonstrate. Conclusion: A four-week treatment with a cream containing 5% α-lipoic acid improves the biomechanical characteristics of the skin, thus contributing to the protection against photo-aging. Both methods of measurement proved to be equivalent.

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Improved understanding of skin elasticity by modelling in vivo mechanical tests

The Essential Stratum Corneum ◽

10.1201/b14296-53 ◽

2002 ◽

pp. 321-323

Author(s):

A Sirvent ◽

M Randeau ◽

C Kurdian ◽

B Closs ◽

F Girard

Keyword(s):

Mechanical Tests ◽

Skin Elasticity

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ANTIAGING PROPERTIES OF CREAM MADE WITH COCOA POLYPHENOL, ALOE VERA (Aloe barbadensis) AND SEAWEED (Euchema cottoni) AS ACTIVE AGENTS Sifat Antiaging dari Krim Berbahan Aktif Polifenol Kakao, Aloe Vera (Aloe barbadensis) dan Rumput Laut (Euchema cottoni)

Jurnal Industri Hasil Perkebunan ◽

10.33104/jihp.v13i1.3760 ◽

2018 ◽

Vol 13 (1) ◽

pp. 43-52

Author(s):

Eky Yenita Ristanti ◽

Sitti Ramlah ◽

Dwi Indriana

Keyword(s):

Wistar Rats ◽

Sodium Dodecyl ◽

Aloe Vera ◽

Active Agent ◽

Polypropylene Glycol ◽

Skin Elasticity ◽

Active Ingredients ◽

Aloe Barbadensis ◽

Male Wistar Rats

Cream made from cocoa polyphenol combined with aloe vera and seaweed has been prepared and its antiaging properties has been studied. Cream composition consisted of cocoa butter, olive oil, sodium dodecyl sulphate, polypropylene glycol, cetyl alcohol and aquadest as the cream base. Cocoa polyphenol, aloe vera and seaweed were used as active agent to perform antiaging activity. Antiaging tests were done in vivo, using male Wistar rats. Antiaging tests included cream effectivity to protect skin from UV B radiation, which indicated by wrinkle, exfoliation, erythema and skin elasticity. Result of this research shows that skin applied with cream contained cocoa polyphenol, aloe vera and seaweed has less wrinkle and erythema after being exposed with UV B lamp for 2 weeks. Cream contained 3 active ingredients (cocoa polyphenol, aloe vera and seaweed) shows less effectivity to protect against exfoliation compare to cream with only 2 active ingredients (aloe vera and seaweed), however, cream with 3 ingredients still shows better protection to skin, compare to the unprotected skin (skin which not applied with any cream). In addition, skin applied with cream contained cocoa polyphenol, aloe vera and seaweed shows better elasticity, compared to those which not applied with cream.

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