Comprehensive and high-resolution typing of swine leukocyte antigen DQA from genomic DNA and determination of 25 new SLA class II haplotypes

2012 ◽  
Vol 80 (6) ◽  
pp. 528-535 ◽  
Author(s):  
M. T. Le ◽  
H. Choi ◽  
M.-K. Choi ◽  
D. T. Nguyen ◽  
J.-H. Kim ◽  
...  
Keyword(s):  
High Resolution ◽  
Genomic Dna ◽  
Class Ii ◽  
Swine Leukocyte Antigen ◽  
Leukocyte Antigen

Systematic analysis of swine leukocyte antigen-DRB1 nucleotide polymorphisms using genomic DNA-based high-resolution genotyping and identification of new alleles

2011 ◽  
Vol 77 (6) ◽  
pp. 572-583 ◽  
Author(s):  
L. Minh Thong ◽  
H. Choi ◽  
O.-J. Kwon ◽  
J.-H. Kim ◽  
Y.-B. Kim ◽  
...  
Keyword(s):  
High Resolution ◽  
Genomic Dna ◽  
Nucleotide Polymorphisms ◽  
Swine Leukocyte Antigen ◽  
Systematic Analysis ◽  
Leukocyte Antigen ◽  
New Alleles

scholarly journals Swine leukocyte antigen class II genes (SLA-DRA, SLA-DRB1, SLA-DQA, SLA-DQB1) polymorphism and genotyping in Guizhou minipigs

2015 ◽  
Vol 14 (4) ◽  
pp. 15256-15266 ◽  
Author(s):  
Z.Z. Liu ◽  
J.H. Xia ◽  
L.L. Xin ◽  
Z.G. Wang ◽  
L. Qian ◽  
...  
Keyword(s):  
Class Ii ◽  
Swine Leukocyte Antigen ◽  
Leukocyte Antigen

scholarly journals Examining the Biosynthesis and Xenoantigenicity of Class II Swine Leukocyte Antigen Proteins

2018 ◽  
Vol 200 (8) ◽  
pp. 2957-2964 ◽  
Author(s):  
Joseph M. Ladowski ◽  
Gregory R. Martens ◽  
Luz M. Reyes ◽  
Zheng-Yu Wang ◽  
Devin E. Eckhoff ◽  
...  
Keyword(s):  
Class Ii ◽  
Swine Leukocyte Antigen ◽  
Leukocyte Antigen

scholarly journals Genetic Association between Swine Leukocyte Antigen Class II Haplotypes and Reproduction Traits in Microminipigs

Cells ◽  
2019 ◽  
Vol 8 (8) ◽  
pp. 783 ◽  
Author(s):  
Ando ◽  
Imaeda ◽  
Matsubara ◽  
Takasu ◽  
Miyamoto ◽  
...  
Keyword(s):  
Litter Size ◽  
Reproductive Traits ◽  
Class Ii ◽  
Swine Leukocyte Antigen ◽  
Low Resolution ◽  
Typing Method ◽  
Leukocyte Antigen ◽  
Fertility Index ◽  
Reproduction Traits ◽  
Small Litter Size

The effects of swine leukocyte antigen (SLA) molecules on numerous production and reproduction performance traits have been mainly reported as associations with specific SLA haplotypes that were assigned using serological typing methods. In this study, we intended to clarify the association between SLA class II genes and reproductive traits in a highly inbred population of 187 Microminipigs (MMP), that have eight different types of SLA class II haplotypes. In doing so, we compared the reproductive performances, such as fertility index, gestation period, litter size, and number of stillbirth among SLA class II low resolution haplotypes (Lrs) that were assigned by a polymerase chain reaction-sequence specific primers (PCR-SSP) typing method. Only low resolution haplotypes were used in this study because the eight SLA class II high-resolution haplotypes had been assigned to the 14 parents or the progenitors of the highly inbred MMP herd in a previous publication. The fertility index of dams with Lr-0.13 was significantly lower than that of dams with Lr-0.16, Lr-0.17, Lr-0.18, or Lr-0.37. Dams with Lr-0.23 had significantly smaller litter size at birth than those with Lr-0.17, Lr-0.18, or Lr-0.37. Furthermore, litter size at weaning of dams with Lr-0.23 was also significantly smaller than those dams with Lr-0.16, Lr-0.17, Lr-0.18, or Lr-0.37. The small litter size of dams with Lr-0.23 correlated with the smaller body sizes of these MMPs. These results suggest that SLA class II haplotypes are useful differential genetic markers for further haplotypic and epistatic studies of reproductive traits, selective breeding programs, and improvements in the production and reproduction performances of MMPs.

Genetic variability in swine leukocyte antigen class II and Toll-like receptors affects immune responses to vaccination for bacterial infections in pigs

2012 ◽  
Vol 35 (6) ◽  
pp. 523-532 ◽  
Author(s):  
H. Shinkai ◽  
A. Arakawa ◽  
M. Tanaka-Matsuda ◽  
H. Ide-Okumura ◽  
K. Terada ◽  
...  
Keyword(s):  
Genetic Variability ◽  
Immune Responses ◽  
Bacterial Infections ◽  
Class Ii ◽  
Swine Leukocyte Antigen ◽  
Toll Like Receptors ◽  
Leukocyte Antigen

Application of high-resolution, massively parallel pyrosequencing for estimation of haplotypes and gene expression levels of swine leukocyte antigen (SLA) class I genes

2011 ◽  
Vol 64 (3) ◽  
pp. 187-199 ◽  
Author(s):  
Yuki F. Kita ◽  
Asako Ando ◽  
Keiko Tanaka ◽  
Shingo Suzuki ◽  
Yuki Ozaki ◽  
...  
Keyword(s):  
Gene Expression ◽  
High Resolution ◽  
Class I ◽  
Massively Parallel ◽  
Swine Leukocyte Antigen ◽  
Expression Levels ◽  
Leukocyte Antigen ◽  
Parallel Pyrosequencing ◽  
Gene Expression Levels

Swine Leukocyte Antigen (SLA) class I allele typing of Danish swine herds and identification of commonly occurring haplotypes using sequence specific low and high resolution primers

2014 ◽  
Vol 162 (3-4) ◽  
pp. 108-116 ◽  
Author(s):  
Lasse Eggers Pedersen ◽  
Gregers Jungersen ◽  
Maria Rathmann Sorensen ◽  
Chak-Sum Ho ◽  
Dorte Fink Vadekær
Keyword(s):  
High Resolution ◽  
Class I ◽  
Swine Leukocyte Antigen ◽  
Leukocyte Antigen ◽  
Swine Herds

scholarly journals The Relationship between the HLA-G Polymorphism and sHLA-G Levels in Parental Pairs with High-Risk Pregnancy

2019 ◽  
Vol 16 (9) ◽  
pp. 1546 ◽  
Author(s):  
Olimpia Sipak ◽  
Aleksandra Rył ◽  
Anna Grzywacz ◽  
Maria Laszczyńska ◽  
Małgorzata Zimny ◽  
...  
Keyword(s):  
Genomic Dna ◽  
Human Leukocyte ◽  
Control Group ◽  
Polish Population ◽  
Leukocyte Antigen ◽  
Risk Pregnancy ◽  
Human Leukocyte Antigen G ◽  
The Relationship ◽  
Class Ib

Human leukocyte antigen G (HLA-G) is observed in immune system cells and other organs. It is a class Ib molecule, which plays a pivotal role in the implantation and maintenance of pregnancy. The aim of this study was to assess the relationship between serum sHLA-G levels and the HLA-G allele in parental pairs with complicated obstetric histories. The clinical material consisted of 210 women and 190 men with the experience of a complicated or an unsuccessful pregnancy. The control group included parents―89 women and 86 men―lacking complicated obstetric histories. We applied genetic analysis methods: isolation of genomic DNA, sequencing, and determination of serum sHLA-G levels. There were no statistically significant differences in the frequencies of the HLA-G −725 C>G polymorphism between particular experimental groups compared with the control group (p > 0.05). The median sHLA-G levels in the women with the HLA-G10101 allele (15.4 U/mL) were significantly higher than in the women with other alleles (p < 0.05). The HLA-G 10101 allele seems to protect against antiphospholipid syndrome, which may be associated with increased serum sHLA-G levels in its carriers. The relationship between serum sHLA-G levels and the HLA-G polymorphisms in the Polish population requires further investigation.

Association of swine leukocyte antigen class II haplotypes and immune-related traits in a swine line selected for resistance to mycoplasmal pneumonia

2016 ◽  
Vol 48 ◽  
pp. 33-40 ◽  
Author(s):  
Asako Ando ◽  
Atsuko Shigenari ◽  
Chihiro Kojima-Shibata ◽  
Mitsuru Nakajoh ◽  
Keiichi Suzuki ◽  
...  
Keyword(s):  
Class Ii ◽  
Swine Leukocyte Antigen ◽  
Leukocyte Antigen ◽  
Mycoplasmal Pneumonia

scholarly journals Swine Leukocyte Antigen Class II Is a Xenoantigen

2018 ◽  
Vol 102 (2) ◽  
pp. 249-254 ◽  
Author(s):  
Joseph M. Ladowski ◽  
Luz M. Reyes ◽  
Gregory R. Martens ◽  
James R. Butler ◽  
Zheng-Yu Wang ◽  
...  
Keyword(s):  
Class Ii ◽  
Swine Leukocyte Antigen ◽  
Leukocyte Antigen
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