Changing trend in the seroprevalence and risk factors of human leptospirosis in the South Andaman Island, India

The Andaman Ophiolite of south-eastern India is located on the outer arc of the Andaman-Java subduction zone. It is represented by thrust slices formed in the Mesozoic Neo-Tethyan Ocean. Lithologically, it consists of dismembered mafic and ultramafic rocks and associated oceanic pelagic sediments. The present study focuses on the mafic cumulate rocks of the Andaman Ophiolite preserved in the Kodiaghat and the Mundapahar area of the South Andaman Island. The mafic cumulates are represented by olivine-bearing and olivine-free gabbros. The sequence of crystallisation in the gabbros is olivines (Fo~80) ± chromian spinels (Cr# 59 - 57), plagioclases (An95−61), clinopyroxenes (Mg# = 89 - 82) and amphiboles (Mg-hornblende, edenite and pargasite). Major oxide and trace element whole rock geochemistry and mineral compositions are consistent with a hybrid signature of Island Arc Tholeiite (IAT) - Mid Oceanic Ridge Basalt (MORB). Geochemical modelling shows that trapped melt fractions of 0 – 20 % can produce the observed trace element signatures of these gabbros. Our findings suggest that the gabbroic cumulates of the Andaman ophiolite were formed in an oceanic back-arc and oceanic arc setting developed in the Neo-Tethyan oceanic domain between the Indian and the Burmese plates during Late Cretaceous age.

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Assessment of risk factors for multifocal atherosclerosis in the workers of the main professions of coal enterprises in the South of Kuzbass

Russian Journal of Occupational Health and Industrial Ecology ◽

10.31089/1026-9428-2020-60-3-157-161 ◽

2020 ◽

pp. 157-161

Author(s):

E. S. Filimonov ◽

O. Yu. Korotenko ◽

O. A. Rumpel ◽

O. N. Blazhina

Keyword(s):

Risk Factors ◽

Cardiovascular Diseases ◽

Arterial Hypertension ◽

Glycated Hemoglobin ◽

Significant Risk ◽

Coal Industry ◽

Atherosclerotic Plaques ◽

The South ◽

Coal Miners ◽

Coal Enterprises

Introduction. The problem of high mortality from cardiovascular diseases is caused, among other things, by asymptomatic atherosclerosis, which proceeds latently for a long time and manifests itself as a serious vascular catastrophe, which is of particular importance for people working at production facilities with difficult and dangerous working conditions.The aim of the study was to assess the risk factors for atherosclerosis and the state of the vascular wall in the workers of the main professions of coal enterprises in the South of Kuzbass.Material and methods. In total, the study included 384 people (men), of whom 266 were the workers in coal mines in the South of Kuzbass and 118 people who were not employed in the coal industry, aged 40 to 55 years. The diagnosis of atherosclerosis was carried out on the ultrasound system “Vivid E9” of the manufacturing company GE using a linear sensor for measuring the thickness of the intima-media complex and visualization of atherosclerotic plaques. To identify significant risk factors, anthropometric, anamnestic data, indices of lipid and carbohydrate metabolism, and the presence of arterial hypertension were studied.Results. Significant differences in the frequency of asymptomatic atherosclerosis in the form of an increase in intima-media thickness by more than 1 mm and / or the presence of atherosclerotic plaques in both groups were not found: 60.2% among the miners and 62.3% among non-coal mining workers (p=0.703); at the same time, the percentage of detection of atherosclerotic plaques in arteries was significantly lower among coal workers — 46.9% versus 60.5% among people in the comparison group (p=0.016). The common risk factors for all examined subjects were arterial hypertension and increased level of glycated hemoglobin; in turn, in coal miners additional risk factors were increased values of low density lipoproteins and waist-hip index, as well as burdened heredity for cardiovascular diseases, and among the individuals not employed in the coal industry it was smoking.Conclusions. The most significant risk factors for atherosclerosis in coal industry workers were arterial hypertension, raised values of glycated hemoglobin, low density lipoproteins and waist-hip index, as well as burdened heredity for cardiovascular diseases. Significant differences in the frequency of asymptomatic atherosclerosis in the form of an increase in the thickness of the intima-media complex of the main arteries and the presence of atherosclerotic plaques in both groups were not established, but the percentage of the detection of atherosclerotic plaques was lower among coal miners.The authors declare no conflict of interests.

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Provenance analysis of the Oligocene turbidites (Andaman Flysch), South Andaman Island: A geochemical approach

Journal of Earth System Science ◽

10.1007/s12040-015-0586-5 ◽

2015 ◽

Vol 124 (5) ◽

pp. 1019-1037 ◽

Cited By ~ 15

Author(s):

P C BANDOPADHYAY ◽

BISWAJIT GHOSH

Keyword(s):

Provenance Analysis ◽

Andaman Island ◽

South Andaman ◽

Andaman Flysch ◽

Geochemical Approach

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Abstract 78: Factors Associated with Thrombotic Events During Pregnancy in the United States: NIS 2000-2010

Stroke ◽

10.1161/str.46.suppl_1.78 ◽

2015 ◽

Vol 46 (suppl_1) ◽

Author(s):

Ali Razmara ◽

Steven Cen ◽

Diana L Jin ◽

Nerses Sanossian ◽

Amytis Towfighi

Keyword(s):

Risk Factors ◽

The United States ◽

The South ◽

Targeted Interventions ◽

Factors Associated ◽

Thrombosis Risk ◽

Significant Difference ◽

Acute Mi ◽

Hospital Factors ◽

Peripartum Period

Intro: Thrombosis risk is increased during pregnancy and puerperium. There are no recent data on nationwide trends in thrombotic events during the delivery period. Objective: To determine risk factors for thrombotic events in women hospitalized for deliveries. Methods: Data from the Nationwide Inpatient Sample (2000-2010) were used to identify deliveries. Weighted proportion of pregnancy hospitalizations with comorbid thrombotic events, including TIA, ischemic stroke, hemorrhagic stroke, acute MI, and venous thromboembolism, was determined. Poisson regression was used to identify risk factors for thrombotic events. The first multivariable model adjusted for sociodemographic and hospital factors. The second model in addition adjusted for comorbid conditions. Results: There were 4,305,561 women hospitalized for delivery (21.5 million US deliveries), of which 7,242 (0.17%) had thrombotic events in the peripartum period. From 2000-2010, there was an increase in deliveries with associated thrombotic events observed from 7.46/10K to 34.8/10K. Compared to 2000, deliveries with thromboses was 8-fold more likely in 2010 (RR 7.94, 95% CI 1.98-31.93). There was no significant difference in rates from 2000 to 2010 after adjustment for sociodemographic and hospital factors. From 2000-2010, pregnant women with thrombotic events were older, more likely to be White, to smoke, to lack insurance, to be admitted to rural hospitals, and to be admitted in the South or Midwest. After multivariable adjustment for sociodemographics, hospital factors, and comorbidities, admissions in the South (RR 1.26, 95% CI 1.02-1.55) or Midwest (1.33, 95% CI 1.05-1.68), atrial fibrillation (1.28, 95% CI 1.01-1.62), pre-/eclampsia (5.78, 95% CI 4.37-7.66), dyslipidemia (1.72, 95% CI 1.42-2.09), atrial septal defect (14.38, 95% CI 6.76-30.58), and valvular heart disease (1.67, 95% CI 1.25-2.24) were independently associated with higher risk of thrombotic events. Conclusions: From 2000-2010, there was a sizeable increase in deliveries with associated thrombosis. Identification of factors associated with thrombotic events for women hospitalized for normal pregnancies will aid in targeted interventions to screen for, prevent and treat thrombosis related to pregnancy.

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