Tissue oxygenation in peripheral muscles and functional capacity in cystic fibrosis: a cross‐sectional study

ObjectiveTo analyse the association between different domains of physical activity (PA) and health-related domains of health-related quality of life (HRQoL) in older adults, independent of confounding variables.DesignCross-sectional study.ParticipantsIn total, 400 individuals 60 years or above were randomly selected to participate in the study.Primary and secondary outcome measuresPA was assessed by a questionnaire in three different domains (work/occupational, sports/gym and leisure time) and total PA. The 36-Item Short Form Health Survey was used to evaluate HRQoL. The variables socioeconomic condition, marital status and presence of health professional-diagnosed comorbidities were self-reported.ResultsThe mean age of the sample was 71.5 (±8.4) years, of whom 58% (n=232) were female. Male older adults showed higher scores of PA in sports, leisure time and in total PA than female adults. Older adults who were more physically active in the work/occupational domain were associated with better scores in functional capacity (OR=1.73, 95% CI 1.02 to 2.93) and general health perception (OR=1.61, 95% CI 1.02 to 2.56). Those who presented a higher score in the sports/gym domain had better scores in functional capacity, even after adjustment for comorbidities (OR=1.72, 95% CI 1.01 to 2.96). Individuals with higher activity in leisure time were more likely to have better scores in functional capacity (OR=1.75, 95% CI 1.03 to 2.98), body pain (OR=1.74, 95% CI 1.09 to 2.78) and mental health (OR=1.67, 95% CI 1.03 to 2.69). Older adults who were more active in total PA were 77% more likely to have better scores in functional capacity (OR=1.77, 95% CI 1.04 to 3.02).ConclusionPhysically active older adults in the different domains of PA presented better HRQoL parameters, reinforcing the importance of studies analysing PA in different contexts and in countries with low and medium socioeconomic conditions.

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Caregiver Coping, Mental Health and Child Problem Behaviours in Cystic Fibrosis: A Cross-Sectional Study

International Journal of Behavioral Medicine ◽

10.1007/s12529-013-9289-y ◽

2013 ◽

Vol 21 (2) ◽

pp. 211-220 ◽

Cited By ~ 9

Author(s):

Jane Sheehan ◽

Harriet Hiscock ◽

John Massie ◽

Adam Jaffe ◽

Margaret Hay

Keyword(s):

Mental Health ◽

Cystic Fibrosis ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Problem Behaviours ◽

Caregiver Coping

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Increased Soluble VCAM-1 and Normal P-Selectin in Cystic Fibrosis: a Cross-Sectional Study

Lung ◽

10.1007/s00408-017-0029-y ◽

2017 ◽

Vol 195 (4) ◽

pp. 445-453 ◽

Cited By ~ 2

Author(s):

Jan K. Nowak ◽

Irena Wojsyk-Banaszak ◽

Edyta Mądry ◽

Andrzej Wykrętowicz ◽

Patrycja Krzyżanowska ◽

...

Keyword(s):

Cystic Fibrosis ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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Quality of life and functional capacity in patients with rheumatoid arthritis – Cross-sectional study

Reumatología Clínica ◽

10.1016/j.reuma.2017.03.002 ◽

2018 ◽

Vol 14 (6) ◽

pp. 360-366 ◽

Cited By ~ 3

Author(s):

Diana Rosa-Gonçalves ◽

Miguel Bernardes ◽

Lúcia Costa

Keyword(s):

Quality Of Life ◽

Rheumatoid Arthritis ◽

Functional Capacity ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei

Thorax ◽

10.1136/thoraxjnl-2018-211567 ◽

2018 ◽

Vol 74 (1) ◽

pp. 87-90 ◽

Cited By ~ 11

Author(s):

Michelle E Wood ◽

Rebecca E Stockwell ◽

Graham R Johnson ◽

Kay A Ramsay ◽

Laura J Sherrard ◽

...

Keyword(s):

Cystic Fibrosis ◽

Staphylococcus Aureus ◽

Pseudomonas Aeruginosa ◽

Cross Sectional Study ◽

Gram Negative Bacteria ◽

Sectional Study ◽

Bacterial Strains ◽

Cross Sectional ◽

Gram Negative ◽

Droplet Nuclei

The airborne route is a potential pathway in the person-to-person transmission of bacterial strains among cystic fibrosis (CF) populations. In this cross-sectional study, we investigate the physical properties and survival of common non-Pseudomonas aeruginosa CF pathogens generated during coughing. We conclude that Gram-negative bacteria and Staphylococcus aureus are aerosolised during coughing, can travel up to 4 m and remain viable within droplet nuclei for up to 45 min. These results suggest that airborne person-to-person transmission is plausible for the CF pathogens we measured.

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Rate of Force Development Remains Reduced in the Knee Flexors 3 to 9 Months After Anterior Cruciate Ligament Reconstruction Using Medial Hamstring Autografts: A Cross-Sectional Study

The American Journal of Sports Medicine ◽

10.1177/0363546520960108 ◽

2020 ◽

Vol 48 (13) ◽

pp. 3214-3223

Author(s):

Jakob Lindberg Nielsen ◽

Kamilla Arp ◽

Mette Lysemose Villadsen ◽

Stine Sommer Christensen ◽

Per Aagaard

Keyword(s):

Functional Capacity ◽

Cruciate Ligament ◽

Knee Extensor ◽

Cross Sectional Study ◽

Healthy Controls ◽

Sectional Study ◽

Cross Sectional ◽

Force Development ◽

Anterior Cruciate ◽

Maximal Muscle Strength

Background: Anterior cruciate ligament (ACL) rupture is a serious injury with a high prevalence worldwide, and subsequent ACL reconstructions (ACLR) appear to be most commonly performed using hamstring-derived (semitendinosus tendon) autografts. Recovery of maximal muscle strength to ≥90% of the healthy contralateral limb is considered an important criterion for safe return to sports. However, the speed of developing muscular force (ie, the rate of force development [RFD]) is also important for the performance of many types of activities in sports and daily living, yet RFD of the knee extensor and flexor muscles has apparently never been examined in patients who undergo ACLR with hamstring autograft (HA). Purpose: To examine potential deficits in RFD, maximal muscle strength (ie, maximal voluntary isometric contraction [MVIC]), and functional capacity of ACLR-HA limbs in comparison with the healthy contralateral leg and matched healthy controls 3 to 9 months after surgery. Study Design: Cross-sectional study; Level of evidence: 3. Methods: A total of 23 young patients who had undergone ACLR-HA 3 to 9 months earlier were matched by age to 14 healthy controls; both groups underwent neuromuscular screening. Knee extensor and flexor MVIC and RFD, as well as functional capacity (single-leg hop for distance [SLHD] test, timed single-leg sit-to-stand [STS] test), were assessed on both limbs. Furthermore, patient-reported knee function (Knee injury and Osteoarthritis Outcome Score) was assessed. Results: Knee extensor and flexor MVIC and RFD were markedly compromised in ACLR-HA limbs compared with healthy contralateral limbs (MVIC for extensor and flexor, 13% and 26%, respectively; RFD, 14%-17% and 32%-39%) and controls (MVIC, 16% and 31%; RFD, 14%-19% and 30%-41%) ( P < .05-.001). Further, ACLR-HA limbs showed reduced functional capacity (reduced SLHD and STS performance) compared with contralateral limbs (SLHD, 11%; STS, 14%) and controls (SLHD, 20%; STS, 31%) ( P < .01-.001). Strength (MVIC) and functional (SLHD) parameters were positively related to the duration of time after surgery ( P < .05), although this relationship was not observed for RFD and STS. Conclusion: Knee extensor and flexor RFD and maximal strength, as well as functional single-leg performance, remained substantially reduced in ACLR-HA limbs compared with noninjured contralateral limbs and healthy controls 3 to 9 months after reconstructive surgery.

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