Effect of treatment with carvacrol and aerobic training on cardiovascular function in spontaneously hypertensive rats

2021 ◽  
Vol 106 (4) ◽  
pp. 891-901
Author(s):  
Herikson Araujo Costa ◽  
Carlos José Moraes Dias ◽  
Vicenilma de Andrade Martins ◽  
Sandra Alves Araujo ◽  
Daiane Pereira da Silva ◽  
...  
Keyword(s):  
Spontaneously Hypertensive Rats ◽  
Aerobic Training ◽  
Cardiovascular Function ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Effect Of Treatment

scholarly journals Effect of Treatment with Peptide Extract from Beef Myofibrillar Protein on Oxidative Stress in the Brains of Spontaneously Hypertensive Rats

Foods ◽  
2019 ◽  
Vol 8 (10) ◽  
pp. 455
Author(s):  
Lee ◽  
Hur
Keyword(s):  
Oxidative Stress ◽  
Spontaneously Hypertensive Rats ◽  
Myofibrillar Protein ◽  
Oxygen Species ◽  
Hypertensive Rats ◽  
Sod Activity ◽  
Spontaneously Hypertensive ◽  
Hypertension Therapy ◽  
Effect Of Treatment ◽  
Gpx Activity

This study was conducted to determine the effect of beef peptide extract on oxidative stress in the brains of spontaneously hypertensive rats (SHRs). A 3-kDa peptide extract was obtained from beef myofibrillar protein using alkaline-AK (AK3K). Oxidative stress in SHR brains was measured by assessing malondialdehyde (MDA) and reactive oxygen species (ROS) concentrations and superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) activity. The SHR brains treated with the AK3K peptide extract (400 mg/kg body weight, AK3K400) showed a significant decrease in MDA and ROS contents by 0.33 and 23.92 μM, respectively (p < 0.05) compared to the control. The SOD activity for AK3K400 was 61.26%, around 20% higher than the control. Furthermore, the SHRs treated with the AK3K peptide extract showed results similar to those obtained using captopril, a hypertension drug, except for the MDA level. The study demonstrates that the beef peptide extract inhibits the generation of oxidative stress in the SHR brain and could possibly be used for neuronal hypertension therapy.

Dissociation between vascular oxidative stress and cardiovascular function in Wistar Kyoto and spontaneously hypertensive rats

2006 ◽  
Vol 45 (2) ◽  
pp. 112-121 ◽  
Author(s):  
Pierre Sicard ◽  
Alexandra Oudot ◽  
Jean-Claude Guilland ◽  
Daniel Moreau ◽  
Catherine Vergely ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Spontaneously Hypertensive Rats ◽  
Cardiovascular Function ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Wistar Kyoto ◽  
Vascular Oxidative Stress

scholarly journals Aerobic Training (T) Improves Cerebral Circulation of Normotensive (WKY) and Spontaneously Hypertensive Rats (SHR)

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Maria Tereza Jordão ◽  
Marina Tuppy Cavalleri ◽  
Katia Burgi ◽  
Alexandre Ceroni ◽  
Lisete Compagno Michelini
Keyword(s):  
Cerebral Circulation ◽  
Spontaneously Hypertensive Rats ◽  
Aerobic Training ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive
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