Cryo-Immunology: Surgical Approach and Thermal Regimen for Freezing the Elements of the Male Rabbit Reproductive System

1972 ◽  
Vol 94 (2) ◽  
pp. 129-132 ◽  
Author(s):  
E. Zappi ◽  
S. Shulman
Keyword(s):  
Surgical Approach ◽  
Reproductive System ◽  
Surgical Techniques ◽  
Living Tissue ◽  
Autoimmune Process ◽  
Host Animal ◽  
Male Rabbit ◽  
Antigenic Properties ◽  
Thermal Regimes

The destructive freezing of living tissue often stimulates the host animal to produce antibodies against its own tissue. This phenomenon, the expression of an autoimmune process, is currently employed in this laboratory for exploring the antigenic properties of the male rabbit reproductive system. In this paper, the anatomic features of this reproductive system are briefly described. Details are offered of the surgical techniques used to approach these organs, and of the thermal regimes used in the destructive freezing of the target tissues.

Cryo-Immunology: The Antigenic Properties of the Male Rabbit Reproductive System as Studied by Selective Freezing of Its Components

1972 ◽  
Vol 94 (2) ◽  
pp. 141-143 ◽  
Author(s):  
S. Shulman ◽  
E. Zappi
Keyword(s):  
Immune Responses ◽  
Reproductive System ◽  
Comparative Studies ◽  
Important Data ◽  
Male Rabbit ◽  
Antigenic Properties ◽  
Immunologic Analysis

Immunologic analysis of antisera and comparative studies of their properties provide important data about the number and the localization of antigens in the various organs of the reproductive system of the rabbit. The advantages of cryostimulation for eliciting immune responses in the reproductive system of the male rabbit are discussed in this paper, and examples are given of the study of such antisera through different immunologic techniques.

scholarly journals Uncommon Location of Lipoma: Extraluminally Vagina

2020 ◽  
Vol 48 ◽  
Author(s):  
Baris Guner ◽  
Nevzat Saat ◽  
Mustafa Usta
Keyword(s):  
Surgical Approach ◽  
Histopathological Examination ◽  
Subcutaneous Tissue ◽  
Surgical Techniques ◽  
Clinical Findings ◽  
Female Reproductive Tract ◽  
Benign Tumors ◽  
Vaginal Mucosa ◽  
Blunt Dissection ◽  
Vaginal Tissue

Background: Lipomas are defined as a soft mass of well-differentiated adipose cells among mesenchymal tumors. Considering the localization of lipomas, these masses are commonly seen in subcutaneous tissue. The female reproductive tract is a rare site for development of lipomas and clinical findings appear depending on the size and localization. The connection of the mass with the vagina lumen causes different clinical findings. Intraluminal tumors protrude and arise from the vulva, while extraluminal tumors lead to perineal swelling. This case describes clinical, ultrasonographic, histological examination, and surgical management of extraluminal vaginal lipoma.Case: The present study reports a case of extraluminal vaginal lipoma in a 10-year-old Pitbull crossbred presented with anamnesis of a protruded tissue from the vulvar lips and dysuria following 6-month swelling in the perineum. Clinical examination revealed that the swelling was obvious and localized mostly on the lower left side of the perineum and the vaginal mucosa was protruded from the vulvar lips due to a mass. By vaginal palpation, the mass was not associated with the vaginal mucosa. The mass was located in the perivaginal region and transvaginal ultrasonography revealed a hypoechogenic mass. Based on clinical and ultrasonographic findings, surgery was recommended. The mass was adherent to the serosa of the vagina and it did not enclose the vaginal mucosa. Excision of mass was performed with careful blunt dissection avoiding any urethral disruption and periurethral tissues. After the mass was determined to be extraluminal, there was no need for excision of the vaginal tissue with the mass during operation. Using histopathological examination the mass was identified as a lipoma composed of adipocytes. In addition, ovariohysterectomy was not recommended following the diagnosis of vaginal lipoma.Discussion: Lipomas uncommonly can be localized in unpredicted rare areas such as vagina and vulva in older bitches. Although the majority of reported benign tumors in dogs recommend the surgery, medical treatment including the steroid injections is the other option to limit the lipomas. Considering the vaginal tumors, the surgical approach is also planned as laparotomy since leiomyomas are more common than lipomas. This approach partially results from the adherence of tumors to vaginal tissue. In addition, the location of the mass together without the adjacent tissue damage depending on whether it is intraluminal or extraluminal would make complete tissue removal. In previous reports, while symptoms such as perineal hernia of the lipoma were emphasized, the connection of the lipoma with the vaginal lumen was not evaluated as a significant factor determining the surgical approach. The mass was not connected to the vaginal mucosa and it was determined as extraluminal lipoma in the present study. Mass excision was performed by blunt dissection, avoiding urethral disruption and periurethral tissues. Unlike the most common approach in leiomyomas, this report did not require a total vaginectomy to remove the mass from the vagina. The ovariohysterectomy was not needed to be performed in the present study as in intraluminal vaginal tumors. It was believed that adhesions of lipoma with vaginal lumen is a determining factor in the combination of surgical techniques such as episiotomy and/or ovariohysterectomy. Lipomas should be considered among the tumors in the vaginal region of dogs brought with the complaint of swelling in perineum and protrusion of vaginal tissue.

scholarly journals Correlation between Age and Surgical Approach for Thoracic and Lumbar Hemivertebra

2020 ◽  
Vol 9 (02) ◽  
pp. 115-121
Author(s):  
Alexandrina Nikova ◽  
Varvara Chatzipaulou ◽  
Belkis Malkots ◽  
Reichan Molla Mustafa ◽  
Christina Valsamidou ◽  
...  
Keyword(s):  
Surgical Approach ◽  
World Literature ◽  
Surgical Techniques ◽  
Spine Deformity ◽  
Optimal Result ◽  
Management Planning ◽  
The World ◽  
The Subject ◽  
The Right ◽  
Future Management

Abstract Objective Hemivertebra (HV) is a congenital defect of the formation of the spinal vertebra, which can result in scoliosis or kyphosis along with the related symptomatology of spine deformity. More often than not, it is linked to other abnormalities and requires attention. Its management is surgical and it is of great importance for the physician to choose the right approach at the right time, due to its deteriorative prognosis. Methods Due to the interest of the subject, the authors investigated the world literature between 1990 and 2018 and found 45 articles, reporting thoracic, thoracolumbar, and lumbar HV in children and its postsurgical outcome, aiming to show whether the approaches are equal in terms of the final outcome. Results The chosen surgical method depends much on the level of the pathology. Despite this fact, after analyzing the included data, we found that the surgical techniques are unequal with regard to the purpose of achieving improvement. Age, caudal and cranial curves, segmental kyphosis, and scoliosis are factors playing a major role in this. Conclusion If not treated, HV leads to deterioration and dysfunction. The most optimal result, however, is achieved only when the surgical approach is applied according to age and rest of the accompanying factors, which should be considered in future management planning.

scholarly journals Periareolar augmentation mastopexy: A new approach dealing with the cases as tuberous breasts

2016 ◽  
Vol 49 (02) ◽  
pp. 172-177 ◽  
Author(s):  
Roberto Moltó-García ◽  
María Eloísa Villaverde-Doménech ◽  
Virina González-Alonso ◽  
Francisco Ripoll-Orts ◽  
Eduardo Simon-Sanz
Keyword(s):  
Surgical Technique ◽  
Surgical Approach ◽  
Surgical Techniques ◽  
Inferior Pole ◽  
Malpractice Claims ◽  
One Year ◽  
Periareolar Mastopexy ◽  
Augmentation Mastopexy ◽  
New Surgical Technique

ABSTRACTBackground: Periareolar augmentation mastopexy is one of the most demanded operations at Plastic Surgery clinics. Nevertheless, it is one of the leads of malpractice claims in United States caused by the high patient expectations and the standard surgical techniques which may result in common complications. The aim of this report is to present a new surgical approach to solve these complications. Methods: After establishing a working hypothesis, we performed a revision study of our patients and we came to the following conclusion: in order to perform a periareolar mastopexy for ptosis correction, breast has to be tuberous at any level and to have abnormally short inferior pole. These findings may explain the main complications from periareolar augmentation mastopexy with the standard surgical techniques. Consequently, we started a prospective observational study including 56 patients following a new surgical technique which deals the cases as tuberous breasts. Results: During three years, fifty-six periareolar mastopexies were performed with this new surgical approach with one year follow-up. No major complications were observed and 40 of the patients (71%) described the results as very positive. Conclusion: “If a periareolar mastopexy can be performed, then it must be a tuberous breast”. According to this, a new surgical technique for periareolar augmentation mastopexy has been developed obtaining an improvement in our surgical results and achieving a totally different view on this pathology, which has not been reported in literature yet.

Immunochemical properties of trypsin fragments of human thyroglobulin

1980 ◽  
Vol 94 (2) ◽  
pp. 188-195 ◽  
Author(s):  
R. Dominici ◽  
G. B. Salabé ◽  
A. Diodato ◽  
M. Sorcini ◽  
M. G. di Iorio ◽  
...  
Keyword(s):  
Gel Filtration ◽  
Rabbit Antiserum ◽  
Antigenic Determinants ◽  
Good Activity ◽  
Autoimmune Process ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Tryptic Digest ◽  
Antigenic Activity ◽  
Antigenic Properties

Abstract. Purified human thyroglobulin (Tg) was enzymatically digested with trypsin. After completion of digestion, the tryptic digest was fractionated by gel filtration on a Biogel A 1.5 m column. Further separation and isolation of the major peak C was carried out on a Sephadex G-75 column. Nine fractions were separated and antigenic properties evaluated by a specific and sensitive radioimmunoassay using a rabbit antiserum to 19S Tg and three different antisera from patients with autoimmune thyroid diseases. The Tg fragments react with both hetero- and auto-antisera. The highest antigenic activity was found on larger fragments, but a fairly good activity was also observed on fragments (C6, C7) with lower molecular weight. Antigenic determinants of Tg differ in individual sera suggesting that different sets of determinants elicit the autoimmune process.

Drooling in oro-motor dyspraxia: is there a role for surgery?

2009 ◽  
Vol 123 (8) ◽  
pp. 931-933 ◽  
Author(s):  
J Rimmer ◽  
B E J Hartley
Keyword(s):  
Cerebral Palsy ◽  
Case Report ◽  
Surgical Approach ◽  
Neurological Disorders ◽  
Surgical Techniques ◽  
Definitive Treatment ◽  
Language Therapy ◽  
Speech And Language Therapy ◽  
Submandibular Duct ◽  
Children With Cerebral Palsy

AbstractObjective:To report the successful use of a surgical approach for the treatment of drooling in a case of oro-motor dyspraxia.Case report:A seven-year-old girl with a diagnosis of oro-motor dyspraxia was referred for management of drooling; this was her only symptom. There were no focal neurological abnormalities. Conservative measures had not helped, and her parents were keen for definitive treatment. Bilateral submandibular duct transposition was performed with no complications. The patient's drooling improved immediately.Conclusion:There are currently no reports in the literature of surgery for persistent drooling in children with oro-motor dyspraxia who are otherwise neurologically and developmentally normal. The mainstay of treatment is speech and language therapy. We report the successful use of surgical techniques, usually reserved for children with cerebral palsy or severe neurological disorders, to treat drooling in an otherwise normal seven-year-old child with oro-motor dyspraxia.

Treatment of acute lower limb ischaemia

VASA ◽  
2016 ◽  
Vol 45 (3) ◽  
pp. 213-221 ◽  
Author(s):  
Aleksander Lukasiewicz
Keyword(s):  
Surgical Approach ◽  
Lower Limb ◽  
Endovascular Procedures ◽  
Surgical Techniques ◽  
Limb Ischaemia ◽  
Lower Limb Ischaemia ◽  
Major Threat ◽  
Wide Range

Abstract. Acute lower limb ischaemia poses a major threat to limb survival. For many years surgical thromboembolectomy was the mainstay of treatment. Recent years have brought an endovascular revolution in the management of acute lower limb ischaemia. A wide range of endovascular procedures can nowadays be employed, providing results at least as good as the traditional surgical approach. This paper is an overview of currently utilised endovascular options as well as recent modifications of standard surgical techniques.

An algorithmic strategy for selecting a surgical approach in cervical deformity correction

2014 ◽  
Vol 36 (5) ◽  
pp. E5 ◽  
Author(s):  
Shannon Hann ◽  
Nohra Chalouhi ◽  
Ravichandra Madineni ◽  
Alexander R. Vaccaro ◽  
Todd J. Albert ◽  
...  
Keyword(s):  
Surgical Management ◽  
Surgical Approach ◽  
Surgical Techniques ◽  
Deformity Correction ◽  
Preoperative Assessment ◽  
Cervical Kyphosis ◽  
Cervical Deformity ◽  
Category Type ◽  
Big Picture ◽  
Algorithmic Strategy

Adult degenerative cervical kyphosis is a debilitating disease that often requires complex surgical management. Young spine surgeons, residents, and fellows are often confused as to which surgical approach to choose due to lack of experience, absence of a systematic method of surgical management, and today's plethora of information regarding surgical techniques. Although surgeons may be able to perform anterior, posterior, or combined (360°) approaches to the cervical spine, many struggle to rationally choose an appropriate approach for deformity correction. The authors introduce an algorithm based on morphology and pathology of adult cervical kyphosis to help the surgeon select the appropriate approach when performing cervical deformity surgery. Cervical deformities are categorized into 5 different prevalent morphological types encountered in clinical settings. A surgical approach tailored to each category/type of deformity is then discussed, with a concrete case illustration provided for each. Preoperative assessment of kyphosis, determination of the goal for surgery, and the complications associated with cervical deformity correction are also summarized. This article's goal is to assist with understanding the big picture for surgical management in cervical spinal deformity.

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