Development of a Biomimetic Masticating Robot for Food Texture Analysis

2021 ◽  
pp. 1-28
Author(s):  
Bangxiang Chen ◽  
Jaspreet Dhupia ◽  
Marco Morgenstern ◽  
John Bronlund ◽  
Weiliang Xu

Abstract Assessing the food texture via mastication is important for advancing knowledge of food properties so as to develop favorable and healthy food products. Oral processing of food by robots can enable an in vitro assessment of food texture by simulating human mastication objectively. In this study, a chewing robot is developed to mimic the rhythmic motion of the molars to enable controllable chewing kinematics and a biomimetic oral environment. The robotic chewing is realized using a 3 degree-of-freedom (DOF) linkage mechanism, which recreates the molar grinding movement based on molar trajectories and chewing cycle durations previously reported in the literature. Moreover, a soft pneumatically actuated cavity is developed to provide a space to contain and reposition the food between occlusions. In order to regulate the robotic chewing having variable molar trajectories and chewing durations, the mathematical relationship of the linkage's actuators and molar movements is investigated for the purpose of motion analysis and control. Accordingly, the design of the robot in terms of linkage, oral cavity and mechatronics system is performed. The built robot is validated by tracing a planned variable molar trajectory while chewing peanuts. The performance of robot chewing is validated by demonstrating the ability of the robot to chew the peanuts similar to that by human through comparison of peanut particle size distributions (PSDs) and particle median size diameters.

2009 ◽  
Vol 62 (11) ◽  
pp. 1528 ◽  
Author(s):  
Carl N. Urbani ◽  
Michael J. Monteiro

We have demonstrated a nanoreactor methodology to produce polystyrene nanoparticles with narrow molecular weight distributions (MWD) and control over the final particle size distributions. Our reactive thermoresponsive diblock copolymer nanoreactor is an ideal setting to carry out otherwise difficult reversible addition–fragmentation chain transfer (RAFT)-mediated polymerizations, resulting in surfactant-free nanoparticles that can be tuned to size and MWD. By confining the MacroRAFT agent within the nanoreactor, the poor P(DMA68-b-NIPAM73)-SC(=S)SC4H9 (PNIPAM) leaving group on the MacroCTA behaves as a highly active MacroCTA through kinetic rather than thermodynamic control. The Mn was close to theory with low polydispersity indices (PDIs) (<1.2). The particle size increased with the ratio of styrene to nanoreactors and with very narrow particle size distributions. However, we found that there was a limited amount of styrene monomer that can be encapsulated into the nanoreactor, leading to polymerizations stopping well before full conversion. This problem was overcome through the addition of a non-reactive thermoresponsive diblock copolymer, which resulted in Mns close to 340 K and low PDIs. Manuscript received: 15 April 2009. Manuscript accepted: 15 July 2009.


2005 ◽  
Vol 24 (6) ◽  
pp. 319-324 ◽  
Author(s):  
K Islas-González ◽  
C González-Horta ◽  
B Sánchez-Ramírez ◽  
E Reyes-Aragón ◽  
M Levario-Carrillo

This in vitro experiment measured the genotoxic effects of ethyl paraoxon, the active metabolite of ethyl parathion. To assess genotoxicity, we used the micronuclei (MN) technique by blocking cytokinesis, and the ‘comet’ assay. We cultured peripheral blood samples from healthy adults and umbilical cord blood samples from four clinically healthy newborns to identify the frequency of MN. After 48 hours, we added the following ethyl paraoxon concentrations to the cultures: 0.0, 0.075, 0.100, 0.160, and 0.200 μg/mL. For the comet assay, following Singh's technique, we treated the blood samples for 2 hours with similar doses of the metabolite. The comet assay results, at a concentration of 0.075 μg/mL, showed that ethyl paraoxon causes a greater DNA migration that followed a dose-response pattern, a greater intensity being observed in lymphocytes from newborns. A comparison of the treatment and control groups indicated that only the 0.200 μg/mL concentration produced a slight increase in MN. In conclusion, our study identified primary DNA damage due to ethyl paraoxon, with a major effect on newborn lymphocytes, as well as an effect on the frequency of MN in the study groups at high concentrations only.


Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
VK Manda ◽  
OR Dale ◽  
C Awortwe ◽  
Z Ali ◽  
IA Khan ◽  
...  

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