scholarly journals An Analysis of 147 Patients with Septicemia at the Department of Internal Medicine of Yamaguchi Prefectural Central Hospital during 16 Years (1968-1983)

1986 ◽  
Vol 60 (5) ◽  
pp. 409-417
Author(s):  
Tetsuhide UNOKI ◽  
Isao NAKAMURA ◽  
Masako KUNIHIRO
2013 ◽  
Vol 24 ◽  
pp. ix38
Author(s):  
F. Fujisawa ◽  
S. Meshihtsuka ◽  
S. Mitsuhashi ◽  
M. Hori ◽  
T. Kaburagi ◽  
...  

2011 ◽  
Vol 73 (5) ◽  
pp. 523-526
Author(s):  
Sakae KANEKO ◽  
Sumiko TAKATSUKA ◽  
Yuko MIHARA ◽  
Kenji TAKAGAKI ◽  
Kyoko NISHIMURA

BMJ Open ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. e018118 ◽  
Author(s):  
Satoshi Shinohara ◽  
Rei Sunami ◽  
Yuzo Uchida ◽  
Shuji Hirata ◽  
Kohta Suzuki

ObjectivePulmonary oedema is recognised as a severe side effect of ritodrine hydrochloride. Recently, the number of twin pregnancies has been increasing. Few studies have reported the association between total dose of ritodrine hydrochloride prior to delivery and pulmonary oedema in twin pregnancy. We aimed to examine this association and determine the optimal cut-off threshold of total ritodrine hydrochloride dose to predict the incidence of pulmonary oedema in twin pregnancy based on obstetric records.DesignRetrospective cohort study.SettingYamanashi Prefectural Central Hospital, Japan.ParticipantsTwo hundred and twenty-six women with twin pregnancy who delivered at Yamanashi Prefectural Central Hospital between September 2009 and November 2016.MethodsThe obstetric records of the participants were analysed. We defined 1 unit of ritodrine hydrochloride as 72 mg per 24 hours continuous transfusion at 50 µg/min to calculate the dose of ritodrine used for tocolysis.Outcome measuresMultivariable logistic regression analysis was performed to examine the association between total dose of ritodrine hydrochloride used for threatened preterm labour and pulmonary oedema, while controlling for potential confounding factors. Then, a receiver–operating characteristic curve was used to determine the optimal cut-off of total ritodrine dose to predict pulmonary oedema incidence.ResultsMean maternal age was 32 (range, 18–46) years; 143 participants were nulliparous (63.3%), 109 had (48.2%) term deliveries and 194 (85.8%) had caesarean deliveries. The overall incidence of pulmonary oedema was 13.7% (31/226). Multivariable analysis showed that the total dose of ritodrine was significantly associated with pulmonary oedema (adjusted OR 1.02; 95% CI 1.004 to 1.03). The best cut-off point to predict the incidence of pulmonary oedema was 26 units (1872 mg) (sensitivity, 61.3%; specificity, 87.8%).ConclusionOur results suggest that consideration of the total dose of ritodrine hydrochloride is helpful in the management of patients with threatened preterm labour in twin pregnancy.


2014 ◽  
Vol 19 (5) ◽  
pp. 13-15
Author(s):  
Stephen L. Demeter

Abstract A long-standing criticism of the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides) has been the inequity between the internal medicine ratings and the orthopedic ratings; in the comparison, internal medicine ratings appear inflated. A specific goal of the AMA Guides, Sixth Edition, was to diminish, where possible, those disparities. This led to the use of the International Classification of Functioning, Disability, and Health from the World Health Organization in the AMA Guides, Sixth Edition, including the addition of the burden of treatment compliance (BOTC). The BOTC originally was intended to allow rating internal medicine conditions using the types and numbers of medications as a surrogate measure of the severity of a condition when other, more traditional methods, did not exist or were insufficient. Internal medicine relies on step-wise escalation of treatment, and BOTC usefully provides an estimate of impairment based on the need to be compliant with treatment. Simplistically, the need to take more medications may indicate a greater impairment burden. BOTC is introduced in the first chapter of the AMA Guides, Sixth Edition, which clarifies that “BOTC refers to the impairment that results from adhering to a complex regimen of medications, testing, and/or procedures to achieve an objective, measurable, clinical improvement that would not occur, or potentially could be reversed, in the absence of compliance.


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