scholarly journals Bacteriological study of Haemophilus influenzae in Niigata Prefectural Central Hospital for four years

2014 ◽  
Vol 63 (1) ◽  
pp. 104-109
Author(s):  
Ayako YAMAMOTO ◽  
Hajime HARADA ◽  
Mieko YAMADA ◽  
Kyuma OTA
2013 ◽  
Vol 24 ◽  
pp. ix38
Author(s):  
F. Fujisawa ◽  
S. Meshihtsuka ◽  
S. Mitsuhashi ◽  
M. Hori ◽  
T. Kaburagi ◽  
...  

2008 ◽  
Vol 52 (7) ◽  
pp. 2480-2485 ◽  
Author(s):  
Pauliina Kärpänoja ◽  
Solja T. Nyberg ◽  
Miika Bergman ◽  
Tinna Voipio ◽  
Pirkko Paakkari ◽  
...  

ABSTRACT The association between trimethoprim-sulfamethoxazole use and resistance among the major respiratory tract pathogens was investigated by comparing regional consumption of the drug to regional resistance in the following year in 21 central hospital districts in Finland. A total of 23,530 Streptococcus pneumoniae isolates, 28,320 Haemophilus influenzae isolates, and 14,138 Moraxella catarrhalis isolates were tested for trimethoprim-sulfamethoxazole susceptibility during the study period (1998-2004). Among the S. pneumoniae isolates, a statistically significant connection was found between regional consumption and resistance. No statistically significant connection was found between regional trimethoprim-sulfamethoxazole use and resistance among H. influenzae and M. catarrhalis isolates. According to our results, it seems that only in pneumococci can the development of trimethoprim-sulfamethoxazole resistance be influenced by restricting its use. However, trimethoprim-sulfamethoxazole remains an important antimicrobial agent because of its reasonable price. Hence, resistance to trimethoprim-sulfamethoxazole among these pathogens needs continuous monitoring.


2011 ◽  
Vol 73 (5) ◽  
pp. 523-526
Author(s):  
Sakae KANEKO ◽  
Sumiko TAKATSUKA ◽  
Yuko MIHARA ◽  
Kenji TAKAGAKI ◽  
Kyoko NISHIMURA

BMJ Open ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. e018118 ◽  
Author(s):  
Satoshi Shinohara ◽  
Rei Sunami ◽  
Yuzo Uchida ◽  
Shuji Hirata ◽  
Kohta Suzuki

ObjectivePulmonary oedema is recognised as a severe side effect of ritodrine hydrochloride. Recently, the number of twin pregnancies has been increasing. Few studies have reported the association between total dose of ritodrine hydrochloride prior to delivery and pulmonary oedema in twin pregnancy. We aimed to examine this association and determine the optimal cut-off threshold of total ritodrine hydrochloride dose to predict the incidence of pulmonary oedema in twin pregnancy based on obstetric records.DesignRetrospective cohort study.SettingYamanashi Prefectural Central Hospital, Japan.ParticipantsTwo hundred and twenty-six women with twin pregnancy who delivered at Yamanashi Prefectural Central Hospital between September 2009 and November 2016.MethodsThe obstetric records of the participants were analysed. We defined 1 unit of ritodrine hydrochloride as 72 mg per 24 hours continuous transfusion at 50 µg/min to calculate the dose of ritodrine used for tocolysis.Outcome measuresMultivariable logistic regression analysis was performed to examine the association between total dose of ritodrine hydrochloride used for threatened preterm labour and pulmonary oedema, while controlling for potential confounding factors. Then, a receiver–operating characteristic curve was used to determine the optimal cut-off of total ritodrine dose to predict pulmonary oedema incidence.ResultsMean maternal age was 32 (range, 18–46) years; 143 participants were nulliparous (63.3%), 109 had (48.2%) term deliveries and 194 (85.8%) had caesarean deliveries. The overall incidence of pulmonary oedema was 13.7% (31/226). Multivariable analysis showed that the total dose of ritodrine was significantly associated with pulmonary oedema (adjusted OR 1.02; 95% CI 1.004 to 1.03). The best cut-off point to predict the incidence of pulmonary oedema was 26 units (1872 mg) (sensitivity, 61.3%; specificity, 87.8%).ConclusionOur results suggest that consideration of the total dose of ritodrine hydrochloride is helpful in the management of patients with threatened preterm labour in twin pregnancy.


Sign in / Sign up

Export Citation Format

Share Document