scholarly journals Differential diagnosis of gallbladder ascariasis debris: the added value of contrast enhanced ultrasound with high frequency transducer

2018 ◽  
Vol 20 (4) ◽  
pp. 413 ◽  
Author(s):  
Yi Dong ◽  
Feng Mao ◽  
Jiaying Cao ◽  
Qi Zhang ◽  
Daohui Yang ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Ultrasound Contrast Agents ◽  
Added Value ◽  
Control Group ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Frequency Transducer ◽  
Real Time Visualization ◽  
High Frequency Transducer ◽  
Diagnostic Modalities

Ascariasis debris of the gallbladder is a very rare incidental or symptomatic presentation. Ascaris debris has a pseudotumorous appearance and may be confused with neoplasia. The aim of the current retrospective study is to investigate the value of contrast enhanced ultrasound (CEUS) for the differential diagnosis of ascariasis debris and neoplasia of the gallbladder.Material and methods: Conventional B-mode ultrasound (BMUS) and CEUS were performed for solitary echo-rich gallbladder lesions. Analysis of the CEUS enhancement pattern of the lesions was conducted according to the current EFSUMB guidelines. Two radiologists assessed the CEUS enhancement patterns in consensus. The final gold standard was surgery with histological examination or imaging follow-up.Results: A total of 9 patients with final diagnoses of gallbladder ascariasis debris were included. As a control group 26 solitary hyperechoic gallbladder lesions without shadowing were included as a control group. The typical zigzag morphology with multiple echogenic parallel lines without shadow were detected inside the lumen of the gallbladder in 6 patients. After injection of 2.4 ml ultrasound contrast agents, all hyperechoic gallbladder ascariasis debris lesions showed no enhancement. All patients in the control group with similar BMUS morphology showed contrast enhancement.Conclusions: Real time visualization of contrast enhancement without radiation exposure is one of the main advantages of CEUS over other diagnostic modalities to differentiate ascariasis debris in the gallbladder from enhancing neoplasia. Thus, surgery and other interventions and their complications could be avoided.

Incidental nonfunctioning pancreatic neuroendocrine tumors: Contrast enhanced ultrasound features in diagnosis

2021 ◽  
pp. 1-10
Author(s):  
Daohui Yang ◽  
Dansong Wang ◽  
Yijie Qiu ◽  
Xiaofan Tian ◽  
Dan Zuo ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Clinical Decision Making ◽  
Ultrasound Contrast Agents ◽  
Arterial Phase ◽  
Control Group ◽  
Pancreatic Neuroendocrine Tumors ◽  
Contrast Enhanced Ultrasound ◽  
Color Flow ◽  
Color Flow Imaging ◽  
Contrast Enhanced

AIM: Preoperative suspicion of malignancy in nonfunctioning pancreatic neuroendocrine tumors (pNETs) is mostly based on tumor size. We retrospectively analyzed the contrast enhanced ultrasound (CEUS) features of a series of histopathologically proved nonfunctioning pNETs. METHODS: In this retrospective study, 37 surgery and histologically proved nonfunctioning pNETs were included. All pNETs lesions were incidentally detected by transabdominal ultrasound. B mode ultrasound (BMUS) and CEUS features were reviewed and analyzed. 52 histopathologically proved pancreatic ductal adenocarcinoma (PDACs) lesions were included as a control group. RESULTS: All nonfunctioning pNETs patients showed no typical clinical symptoms. No significant differences were observed in size, echogenicity or internal color flow imaging signal between pNETs and PDAC patients (P >  0.05). Most of nonfunctioning pNETs showed a well-defined tumor margin. The presence of pancreatic duct dilatation was less frequently observed in nonfunctioning pNETs patients (P <  0.05). After injection of ultrasound contrast agents, homogeneous enhancement was more commonly observed in nonfunctioning pNETs group (P <  0.05). During arterial phase of CEUS, most of nonfunctioning pNETs were hyper- or isoenhanced (32/37, 86.5%), whereas most of PDACs were hypoenhanced (34/52, 65.4%) (P <  0.05). Nonenhanced necrosis area was more commonly detected in PDACs (P = 0.012). CONCLUSIONS: CEUS features are helpful for preoperative non-invasive differential diagnosis of nonfunctioning pNETs, assisting further clinical decision-making process.

scholarly journals Detection and characterization of small superficially located focal liver lesions by contrast-enhanced ultrasound with high frequency transducers

2017 ◽  
Vol 19 (4) ◽  
pp. 349 ◽  
Author(s):  
Wen-Ping Wang ◽  
Yi Dong ◽  
Jiaying Cao ◽  
Feng Mao ◽  
Yadan Xu ◽  
...  
Keyword(s):  
High Frequency ◽  
Low Frequency ◽  
Focal Liver Lesions ◽  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Frequency Transducer ◽  
High Frequency Transducer ◽  
Sensitivity Specificity

Aim: To evaluate the benefits of contrast-enhanced ultrasound (CEUS) with high frequency transducers in the detection and characterization of small superficially located focal liver lesions (FLLs).Material and methods: From January 2015 to October 2016, 27 superficial FLLs detected by MRI were examined, first with the low frequency convex transducer (1-5 MHz) and afterwards with a high frequency transducer (7.5-12 MHz). High frequency dynamic CEUS was performed after a bolus injection of 2.4 ml SonoVue®. FLLs were confirmed by histopathology after surgery (n=18) or ultrasound guided 18-gauge core-needle biopsy (n=8), or by MRI follow-up (n =1).Results: The mean diameter of FLLs was 10.5±3.1 mm, and meandepth was 6.2±5.3 mm. While using a high frequency transducerthe detection rate of FLLs (100%, 27/27) was significantly higher than low frequency transducer (25.9%, 7/27) (p<0.05). The overall sensitivity, specificity and diagnostic accuracy were significantly improved by CEUS with a high frequency transducer (sensitivity 88.9%; specificity 92.6%; accuracy 96.2%).Conclusion: Combining CEUS with the performance of high-frequency transducers is a promising technique to improve the detection and accurate diagnosis of small and superficial FLLs appearing indistinctive on BMUS.

scholarly journals Added value of contrast-enhanced ultrasound (CEUS) in the diagnosis of primary retroperitoneal serous adenocarcinoma: a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lin-Yu Zhou ◽  
Xiao-Dan Zhu ◽  
Jian Jiang ◽  
Yan-Feng Bai ◽  
Tian-An Jiang
Keyword(s):  
Differential Diagnosis ◽  
Transvaginal Ultrasound ◽  
Final Diagnosis ◽  
Added Value ◽  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Serous Adenocarcinoma ◽  
Contrast Enhanced ◽  
Chocolate Cyst ◽  
Primary Retroperitoneal

Abstract Background Primary retroperitoneal serous adenocarcinoma (PRSA) is a rare malignant disease. Given the rarity of the disease, the imaging features of PRSA are unclear. Contrast-enhanced ultrasound (CEUS) also plays an important role in the evaluation of the differential diagnosis of retroperitoneal lesions. Case presentation We report the case of a 62-year-old woman of with increased CA125 levels for 1 year who was referred to our hospital. After conducting contrast-enhanced computed tomography and magnetic resonance imaging, the mass was misdiagnosed as a chocolate cyst. After transvaginal ultrasound (TUS) combined with CEUS, cystadenocarcinoma was considered as the initial diagnosis. Pathology results confirmed PRSA as the final diagnosis. Conclusions CEUS features of PRSA are reported for the first time based on this case, potentially aiding in the differential diagnosis of this rare entity before surgery.

scholarly journals Contrast-enhanced ultrasound of pediatric lungs

2021 ◽  
Author(s):  
Vasileios Rafailidis ◽  
Savvas Andronikou ◽  
Hans-Joachim Mentzel ◽  
Maciej Piskunowicz ◽  
Judy H. Squires ◽  
...  
Keyword(s):  
Pleural Cavity ◽  
Imaging Modality ◽  
Fibrinolytic Therapy ◽  
Community Acquired Pneumonia ◽  
Ultrasound Contrast Agents ◽  
Added Value ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Clinical Scenarios ◽  
Current Experience

AbstractIn addition to radiography, ultrasound (US) has long proved to be a valuable imaging modality to evaluate the pediatric lung and pleural cavity. Its many inherent advantages, including real-time performance, high spatial resolution, lack of ionizing radiation and lack of need for sedation make it preferable over other imaging modalities such as CT. Since the introduction of ultrasound contrast agents (UCAs), contrast-enhanced ultrasound (CEUS) has become a valuable complementary US technique, with many well-established uses in adults and evolving uses in children. Lung CEUS applications are still not licensed and are performed off-label, although the added value of CEUS in certain clinical scenarios is increasingly reported. The limited evidence of CEUS in the evaluation of pediatric lungs focuses primarily on community-acquired pneumonia and its complications. In this clinical setting, CEUS is used to confidently and accurately diagnose necrotizing pneumonia and to delineate pleural effusions and empyema. In addition to intravenous use, UCAs can be administered directly into the pleural cavity through chest catheters to improve visualization of loculations within a complex pleural effusion, which might necessitate fibrinolytic therapy. The purpose of this paper is to present the current experience on pediatric lung CEUS and to suggest potential additional uses that can be derived from adult studies.

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