Background:
The approach for the determination of aminoimidazo-azaarenes (AIAs) is urgent required due to
their mutagenic activity and potential carcinogenicity. For this purpose, a CdSe/ZnS quantum dots (CdSe/ZnS QDs) -
embedded molecularly imprinted silica gel with high selectivity and sensitivity was successfully prepared and applied to
analyze such target.
Methods:
Herein, CdSe/ZnS QDs acted as the fluorescent probe, and molecularly imprinted silica gel as recognition probe
was synthesized on the surface of QDs via sol-gel method. 2-Aminobenzimidazole, which has a similar structure with
AIAs, as well as low cost and low toxicity, was selected as the dummy template.
Results:
The material has a high imprinting factor (IF=6.15); the linear range of CdSe/ZnS@MIP as a fluorescent sensing
material for AIAs is 0.5-20.0 μg L
-1 with the limit of detection (LOD) of 0.25 μg L
-1
(3σ/s). Moreover, the fluorescent
materials have been further applied to determine AIAs in beef floss and grilled fish fillet with satisfactory recoveries
(82.8-110.8 %), and the relative standard deviation (RSD) is < 5.5%.
Conclusion:
The proposed CdSe/ZnS QDs-embedded molecularly imprinted silica gel can be used to easily and
selectively detect AIAs.
Synthesis and Evaluation of Molecularly Imprinted Silica Gel for 2-Hydroxybenzoic Acid in Aqueous Solution