Rotational diffusion of nucleosomes: role of the N-terminal histone domains in structural transitions

1992 ◽  
Author(s):  
David W. Brown ◽  
Enoch W. Small
Keyword(s):  
Rotational Diffusion ◽  
Structural Transitions

A stochastic roadmap method to model protein structural transitions

Robotica ◽  
2015 ◽  
Vol 34 (8) ◽  
pp. 1705-1733 ◽  
Author(s):  
Kevin Molloy ◽  
Rudy Clausen ◽  
Amarda Shehu
Keyword(s):  
Protein Structure ◽  
Molecular Basis ◽  
Structure And Function ◽  
Structural Transitions ◽  
Simulation Framework ◽  
Human Disorders ◽  
Model Protein ◽  
And Function ◽  
The Impact

SUMMARYEvidence is emerging that the role of protein structure in disease needs to be rethought. Sequence mutations in proteins are often found to affect the rate at which a protein switches between structures. Modeling structural transitions in wildtype and variant proteins is central to understanding the molecular basis of disease. This paper investigates an efficient algorithmic realization of the stochastic roadmap simulation framework to model structural transitions in wildtype and variants of proteins implicated in human disorders. Our results indicate that the algorithm is able to extract useful information on the impact of mutations on protein structure and function.

Atomic Number Dependent “Structural Transitions” in Ordered Lanthanide Monolayers: Role of the Hydration Shell

Langmuir ◽  
2017 ◽  
Vol 33 (6) ◽  
pp. 1412-1418 ◽  
Author(s):  
Mitchell Miller ◽  
Miaoqi Chu ◽  
Binhua Lin ◽  
Wei Bu ◽  
Pulak Dutta
Keyword(s):  
Atomic Number ◽  
Hydration Shell ◽  
Structural Transitions

scholarly journals The Role of Unstructured Extensions in the Rotational Diffusion Properties of a Globular Protein: The Example of the Titin I27 Module

2004 ◽  
Vol 87 (2) ◽  
pp. 1227-1240 ◽  
Author(s):  
Giuseppe Nicastro ◽  
Paola Margiocco ◽  
Barbara Cardinali ◽  
Paola Stagnaro ◽  
Fabio Cauglia ◽  
...  
Keyword(s):  
Rotational Diffusion ◽  
Globular Protein ◽  
Diffusion Properties
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