Approximating monomer diffusion in the Raman-Nath regime

2010 ◽  
Author(s):  
C. E. Close ◽  
M. R. Gleeson ◽  
J. T. Sheridan
Keyword(s):  
1990 ◽  
Vol 58 (4) ◽  
pp. 1067-1073 ◽  
Author(s):  
M.R. Cho ◽  
F.A. Ferrone

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Jyoji Morise ◽  
Kenichi G. N. Suzuki ◽  
Ayaka Kitagawa ◽  
Yoshihiko Wakazono ◽  
Kogo Takamiya ◽  
...  

AbstractThe number and subunit compositions of AMPA receptors (AMPARs), hetero- or homotetramers composed of four subunits GluA1–4, in the synapse is carefully tuned to sustain basic synaptic activity. This enables stimulation-induced synaptic plasticity, which is central to learning and memory. The AMPAR tetramers have been widely believed to be stable from their formation in the endoplasmic reticulum until their proteolytic decomposition. However, by observing GluA1 and GluA2 at the level of single molecules, we find that the homo- and heterotetramers are metastable, instantaneously falling apart into monomers, dimers, or trimers (in 100 and 200 ms, respectively), which readily form tetramers again. In the dendritic plasma membrane, GluA1 and GluA2 monomers and dimers are far more mobile than tetramers and enter and exit from the synaptic regions. We conclude that AMPAR turnover by lateral diffusion, essential for sustaining synaptic function, is largely done by monomers of AMPAR subunits, rather than preformed tetramers.


2006 ◽  
Vol 207 (17) ◽  
pp. 1539-1545 ◽  
Author(s):  
Kristofer J. Thurecht ◽  
David J. T. Hill ◽  
Andrew K. Whittaker

2007 ◽  
Vol 21 (15) ◽  
pp. 941-953 ◽  
Author(s):  
P. YU. GUBANOV ◽  
I. L. MAKSIMOV ◽  
V. P. MOROZOV

The kinetics of the Ostwald ripening in a homogeneous supersaturated solution is studied both numerically and analytically. The time evolution of the grain-size distribution function in a new phase is theoretically described, taking into account the finite value of the maximal size of a grain. Two situations are considered: the kinetics of grain growth is controlled either by the grain-monomer reaction process (an early stage) or by the monomer diffusion process (a late stage). A transition to the final distribution is shown to take place through an intermediate-asymptotical mode of the Ostwald ripening kinetics, the crossover of the kinetic indices is demonstrated, and the duration of intermediate stage is evaluated.


Sign in / Sign up

Export Citation Format

Share Document