TU-A-WAB-04: A Prospective Longitudinal Study with Ultrasound Nakagami Imaging to Evaluate the Relationship Between Acute and Late Normal-Tissue Toxicity in Breast-Cancer Radiotherapy

Purpose The purpose of this paper is to investigate the relationship between resting heart rate (RHR) and psychopathy. The literature on heart rate vs criminality (including violence) is quite clear; low RHR is associated with engaging in violent and criminal behavior. However, results are not as consistent for psychopathy. Design/methodology/approach This paper analyzes heart rate measured at ages 18 and 48, and psychopathy at age 48, in the Cambridge Study in Delinquent Development (CSDD). The CSDD is a prospective longitudinal study that has followed 411 boys from childhood to middle age, and measured social and biological factors of interest to the field of criminal psychology. Findings Interestingly, it was only heart rate at age 18 that was negatively and significantly related to psychopathy at age 48. No trends or relationships were found between heart rate at age 48 and psychopathy at age 48. The findings do, however, indicate that low heart rate at age 18 predicts psychopathy at age 48, and the strongest negative relationships are found between low heart rate (beats per minute) and impulsive and antisocial psychopathic symptoms. Originality/value This is the first ever longitudinal study showing that low RHR predicts later psychopathy. Suggestions for future research are outlined.

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Does fear of movement mediate the relationship between pain intensity and disability in patients following whiplash injury? A prospective longitudinal study

Pain ◽

10.1016/j.pain.2011.09.023 ◽

2012 ◽

Vol 153 (1) ◽

pp. 113-119 ◽

Cited By ~ 35

Author(s):

Steven J. Kamper ◽

Christopher G. Maher ◽

Luciola da C. Menezes Costa ◽

James H. McAuley ◽

Julia M. Hush ◽

...

Keyword(s):

Longitudinal Study ◽

Pain Intensity ◽

Whiplash Injury ◽

Prospective Longitudinal Study ◽

Fear Of Movement ◽

Prospective Longitudinal ◽

The Relationship

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Abstract P1-10-07: Prospective longitudinal study of epidermal thickening in breast cancer patients treated with conventional versus hypofractionated radiotherapy

10.1158/1538-7445.sabcs16-p1-10-07 ◽

2017 ◽

Author(s):

MA Torres ◽

X Yang ◽

D Mister ◽

A Ali ◽

S Kahn ◽

...

Keyword(s):

Breast Cancer ◽

Longitudinal Study ◽

Cancer Patients ◽

Hypofractionated Radiotherapy ◽

Breast Cancer Patients ◽

Prospective Longitudinal Study ◽

Prospective Longitudinal

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IMPACT OF ADJUVANT CHEMOTHERAPY OR TAMOXIFEN ALONE ON THE OVARIAN RESERVE OF YOUNG WOMEN WITH BREAST CANCER: A PROSPECTIVE LONGITUDINAL STUDY

Fertility and Sterility ◽

10.1016/j.fertnstert.2020.09.051 ◽

2020 ◽

Vol 114 (3) ◽

pp. e536-e537

Author(s):

Kutluk H. Oktay ◽

Volkan Turan ◽

Giuliano Bedoschi ◽

Enes Taylan ◽

Heejung Bang ◽

...

Keyword(s):

Breast Cancer ◽

Longitudinal Study ◽

Adjuvant Chemotherapy ◽

Young Women ◽

Ovarian Reserve ◽

Prospective Longitudinal Study ◽

Prospective Longitudinal

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Dosimetric Evaluation of Critical Organs at Risk in Mastectomized Left-Sided Breast Cancer Radiotherapy Using Breath-Hold Technique

Tumori Journal ◽

10.1177/030089161309900113 ◽

2013 ◽

Vol 99 (1) ◽

pp. 76-82 ◽

Cited By ~ 8

Author(s):

Ferrat Dincoglan ◽

Murat Beyzadeoglu ◽

Omer Sager ◽

Kaan Oysul ◽

Yelda Elcim Kahya ◽

...

Keyword(s):

Breast Cancer ◽

Coronary Artery ◽

Adjuvant Radiotherapy ◽

Normal Tissue ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Breath Hold ◽

Cancer Radiotherapy ◽

Breast Cancer Radiotherapy ◽

Tissue Sparing

Aims and background The aim of the study was to evaluate the dosimetric impact of the active breathing control-moderate deep inspiration breath-hold (ABC-mDIBH) technique on normal tissue sparing in locally advanced left-sided breast cancer radiotherapy. Methods and study design Twenty-seven consecutive patients with left-sided locally advanced breast cancer referred to our department for adjuvant radiotherapy were enrolled in the study. Each patient was scanned at free breathing and ABC-mDIBH for radiation treatment planning. Two separate radiotherapy treatment plans were generated with and without ABC-mDIBH to investigate the dosimetric impact of ABC-mDIBH in breast cancer radiotherapy. Results Between June 2011 and February 2012, 27 consecutive patients with left-sided locally advanced breast cancer referred to our department for adjuvant radiotherapy were enrolled in the study. Dose-volume parameters of left anterior descending coronary artery, lungs, heart, contralateral breast, esophagus and spinal cord were significantly reduced with the use of ABC-mDIBH ( P <0.001). Conclusions Our study revealed that the use of ABC-mDIBH in the practice of locally advanced mastectomized left-sided breast cancer radiotherapy improves normal tissue sparing with the expected potential of decreasing treatment-related morbidity and mortality. Moreover, the resultant reduction achieved with ABC in doses to the left anterior descending coronary artery, which plays a central role in cardiac perfusion, may have implications for decreasing the potential of radiation-induced cardiac morbidity and mortality.

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