Molybdenum metabolism studied by means of stable tracers

1992 ◽  
Vol 19 (2) ◽  
pp. 439-444 ◽  
Author(s):  
M. C. Cantone ◽  
D. de Bartolo ◽  
N. Molho ◽  
L. Pirola ◽  
G. Gambarini ◽  
...  
Keyword(s):  
1993 ◽  
Vol 170 (2) ◽  
pp. 433-442 ◽  
Author(s):  
M. C. Cantone ◽  
D. De Bartolo ◽  
G. Gambarini ◽  
A. Giussani ◽  
N. Molho ◽  
...  

1980 ◽  
Vol 14 (2) ◽  
pp. 180-180
Author(s):  
D Del Principe ◽  
R Cesareo ◽  
B M Tallarida ◽  
V G Ciancarelli ◽  
A Menichelli ◽  
...  

2019 ◽  
Vol 107 (3) ◽  
pp. 233-242 ◽  
Author(s):  
Nazila Gholipour ◽  
Mehdi Akhlaghi ◽  
Amin Mokhtari Kheirabadi ◽  
Mahdi Fasihi Ramandi ◽  
Ali Farashahi ◽  
...  

Abstract To develop a possible PET blood pool imaging agent, a series 68Ga-dextran carboxylate derivatives were prepared. Dextran carboxylates with different degree of oxidations (DO) were prepared through stepwise dextran oxidation using NaIO4 and CH3COOOH. The products were characterized by FT-IR and GPC, followed by solubility and toxicity tests on Hella cells (viability=98.6, 97.4 and 95.6% for 3 dextran carboxylates with DOs: 8.3, 24.6 and 39.8%, respectively. The products were labeled with 68Ga (radiochemical purity>98%; ITLC) followed by stability tests in final solution as well as in presence of cycteine and human serum. Two stable tracers (DOs; 24.6 and 39.8%) were adminstered intravenously into wild type rat tail vein separately demonstrating suitable retention in circulation as expected from blood pool imaging agents. Liver and spleen also contained activities. The major excretion was through urinary pathway esp. for derivative with DO. 39.8%. Unlike 68Ga-dextran, lungs showed lower uptake. The dextran carboxylate with the highest 39.8% showed the best characteristics for a blood pool agent, though more studies including PET imaging in larger mammals are required.


1988 ◽  
Vol 15 (6) ◽  
pp. 862-866 ◽  
Author(s):  
M. C. Cantone ◽  
N. Molho ◽  
L. Pirola ◽  
G. Gambarini ◽  
Ch. Hansen ◽  
...  

1981 ◽  
Vol 6 ◽  
Author(s):  
Thomas E. Hakonson ◽  
Ernest S. Gladney

ABSTRACTThe long-term integrity of low-level waste shallow land burial sites is dependent on the interaction of physical, chemical, and biological factors that modify the waste containment system. Past research on low-level waste shallow land burial methods has emphasized physical (i.e., water infiltration, soil erosion) and chemical (radionuclide leaching) processes that can cause waste site failure and subsequent radionuclide transport.The purpose of this paper is to demonstrate the need to consider biological processes as being potentially important in reducing the integrity of waste burial site cover treatments. Plants and animals not only can transport radionuclides to the ground surface via root systems and soil excavated from the cover profile by animal burrowing activities, but they modify physical and chemical processes within the cover profile by changing the water infiltration rates, soil erosion rates and chemical composition of the soil.One approach to limiting biological intrusion through the waste cover is to apply a barrier within the profile to limit root and animal penetration with depth. Experiments in the Los Alamos Experimental Engineered Test Facility were initiated to develop and evaluate biological barriers that are effective in minimizing intrusion into waste trenches. The experiments that are described employ four different candidate barrier materials of geologic origin. Experimental variables that will be evaluated, in addition to barrier type, are barrier depth and soil overburden depth. The rate of biological intrusion through the various barrier materials is being evaluated through the use of activatable stable tracers.


2000 ◽  
Vol 39 (1) ◽  
pp. 53-58 ◽  
Author(s):  
D. de Bartolo ◽  
M.C. Cantone ◽  
A. Giussani ◽  
L. Garlaschelli ◽  
P. Roth ◽  
...  

2002 ◽  
Vol 374 (4) ◽  
pp. 588-591 ◽  
Author(s):  
Schmidt H. ◽  
Fielitz P. ◽  
Borchardt G. ◽  
Weber S. ◽  
Scherrer H. ◽  
...  

2007 ◽  
Vol 127 (1-4) ◽  
pp. 136-139 ◽  
Author(s):  
A. Giussani ◽  
M. C. Cantone ◽  
V. Hollriegl ◽  
U. Oeh ◽  
F. Tavola ◽  
...  

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