scholarly journals Anatomy-based definition of point A utilizing three-dimensional volumetric imaging approach for high-dose-rate (HDR) intracavitary brachytherapy dose prescription when treating cervical cancer using limited resources

2016 ◽  
Vol 17 (6) ◽  
pp. 69-77
Author(s):  
Manish K. Goyal ◽  
D.V. Rai ◽  
Than S. Kehwar ◽  
Jayanand Manjhi ◽  
Bret H. Heintz ◽  
...  
2022 ◽  
Vol 11 ◽  
Author(s):  
Jun Itami ◽  
Naoya Murakami ◽  
Miho Watanabe ◽  
Shuhei Sekii ◽  
Takahiro Kasamatsu ◽  
...  

High-dose-rate brachytherapy by remote afterloading is now performed under three-dimensional image guidance by CT or MRI. Three-dimensional image-guided brachytherapy in cervical cancer disclosed that the traditional intracavitary brachytherapy by Manchester method cannot deliver an adequate dose to the large tumor with resulting local recurrence. To improve the local control rate, combined interstitial and intracavitary (hybrid) brachytherapy can increase the dose to the large parametrial involvement without increasing the dose to the rectum and bladder. Whether hybrid brachytherapy can be performed safely on a multi-institutional basis remains to be studied. From 2015, phase I/II study of hybrid brachytherapy was launched in Japan, and it was revealed that hybrid brachytherapy can be performed safely and with a high quality of radiation dose distribution in a multi-institutional study. In Japan, the number of patients undergoing hybrid brachytherapy in cervical cancer is rapidly rising. Education and clinical trial are very important to establish hybrid brachytherapy in the management of cervical cancer.


BMC Cancer ◽  
2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Naoya Murakami ◽  
Takahiro Kasamatsu ◽  
Akihisa Wakita ◽  
Satoshi Nakamura ◽  
Hiroyoki Okamoto ◽  
...  

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