Tongue position variability in sustained vowels produced by healthy children and young adults with and without a semi-occluded vocal tract: A pilot study

AIM: To evaluate retinal parameters in a sample of healthy young Caucasian adults to define the normal or physiological range of inter-ocular asymmetry in this particular age and ethnic group. METHODS: Study sample consisted of 37 Caucasian children and young adults aged between 12 and 23y (spherical equivalent from -3.00 D to +4.00 D, anisometropia <0.5 D and axial length differences <0.3 mm). Normal inter-ocular asymmetry values were determined and 95% inter-ocular difference tolerance values were obtained. RESULTS: Statistically significant inter-ocular differences were found in mean (P=0.003) and superior (P=0.008) retinal nerve fiber layer (RNFL) thickness, as well as in central macular thickness (P=0.039), with larger values in the left eye in all instances, and with tolerance limits of inter-ocular asymmetry of -9.00 µm to 6.00 µm, -28.00 µm to 9 µm and -39.00 µm to 29.00 µm, respectively. In addition, statistically significant differences were found between males and females in mean thickness of the RNFL in the right eye (P=0.020). CONCLUSION: The exploration of the normal asymmetries of the retina may be an effective approach to further understand myopia onset and progression, which is particularly relevant in this age group. Differences in instrumentation and sample characteristics compromise direct comparison with published research and warrant the need for further studies.

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12-month assessment of increase in total kidney volume in children and young adults with autosomal dominant polycystic kidney disease – a pilot study

Annales Academiae Medicae Silesiensis ◽

10.18794/aams/69244 ◽

2017 ◽

Vol 71 ◽

pp. 109-115

Author(s):

Monika Pawlak-Bratkowska ◽

Susan Afshari ◽

Piotr Grzelak ◽

Michał Podgórski ◽

Agnieszka Wosiak ◽

...

Keyword(s):

Young Adults ◽

Pilot Study ◽

Kidney Disease ◽

Polycystic Kidney Disease ◽

Autosomal Dominant ◽

Kidney Volume ◽

Polycystic Kidney ◽

Total Kidney Volume ◽

Children And Young Adults ◽

Autosomal Dominant Polycystic Kidney

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Hand size representation in healthy children and young adults

Journal of Experimental Child Psychology ◽

10.1016/j.jecp.2020.105016 ◽

2021 ◽

Vol 203 ◽

pp. 105016

Author(s):

Ruth Van der Looven ◽

Miguel Deschrijver ◽

Linda Hermans ◽

Martine De Muynck ◽

Guy Vingerhoets

Keyword(s):

Young Adults ◽

Healthy Children ◽

Hand Size ◽

Children And Young Adults

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Abstract 3882: Clinical exome and transcriptome sequencing for identification of actionable cancer targets: A pilot study for children and young adults with relapsed or refractory solid tumors

10.1158/1538-7445.am2015-3882 ◽

2015 ◽

Author(s):

Wen-I Chang ◽

Andrew S. Brohl ◽

Rajesh Patidar ◽

Jack F. Shern ◽

Jun S. Wei ◽

...

Keyword(s):

Young Adults ◽

Pilot Study ◽

Solid Tumors ◽

Transcriptome Sequencing ◽

Children And Young Adults

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Management and Outcomes of Atrial Fibrillation in 241 Healthy Children and Young Adults: Revisiting “Lone” Atrial Fibrillation. A Multi-Institutional PACES Collaborative Study

Heart Rhythm ◽

10.1016/j.hrthm.2021.07.066 ◽

2021 ◽

Author(s):

Iqbal El Assaad ◽

Benjamin H. Hammond ◽

Lukas D. Kost ◽

Sarah Worley ◽

Christopher M. Janson ◽

...

Keyword(s):

Atrial Fibrillation ◽

Young Adults ◽

Collaborative Study ◽

Healthy Children ◽

Lone Atrial Fibrillation ◽

Children And Young Adults

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Evaluation of insulin resistance in a cohort of HIV-infected youth

Acta Endocrinologica ◽

10.1530/eje-07-0414 ◽

2007 ◽

Vol 157 (5) ◽

pp. 655-659 ◽

Cited By ~ 22

Author(s):

Raffaella Rosso ◽

Arianna Parodi ◽

Giuseppe d'Annunzio ◽

Francesca Ginocchio ◽

Laura Nicolini ◽

...

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Young Adults ◽

Antiretroviral Therapy ◽

Serum Insulin ◽

Targeted Prevention ◽

Healthy Children ◽

Model Assessment ◽

Insulin Levels ◽

Children And Young Adults

AbstractObjectiveMetabolic abnormalities, including impairment of glucose homeostasis, have been well characterized in HIV-infected patients. In contrast to adults, insulin resistance and diabetes mellitus appear to be relatively uncommon finding in youth.DesignWe assessed insulin resistance, and associated risk factors, in a population of vertically HIV-infected children and young adults, when compared with a control population of healthy children.MethodsAt the time of enrolment, weeks of pregnancy, birth weight, sex, age, weight, height, body mass index (BMI), pubertal stages, CDC classification, blood pressure, clinical lipodystrophy, hepatitis B or C co-infection, antiretroviral therapy, CD4 T lymphocyte counts, and HIV-RNA levels were recorded. Fasting plasma glucose and insulin levels and homeostatic model assessment-insulin resistance (HOMA-IR) were determined. These parameters were compared between HIV patients and healthy controls with multivariate analyses.ResultsFasting insulin levels (OR=1.21, P<0.001) and glycemia (OR=0.89, P<0.001) were significantly different between HIV-infected patients and controls. Antiretroviral therapy duration (r=0.281, P<0.05), triglyceride levels (r=0.286, P<0.05), age (r=0.299, P<0.05), and BMI SDS (r=0.485, P<0.001) were significant predictor variables of insulin resistance, expressed as HOMA-IR. Moreover, clinical lipodystrophy seems to be strongly correlated to glycemia (P<0.05), triglyceride levels (P<0.05), serum insulin levels (P<0.001), HOMA-IR (P<0.05), and also with therapy duration (P<0.05).ConclusionsBoth HIV infection and antiretroviral therapy demonstrate differential effects on glucose metabolism in HIV-infected children. Targeted prevention of insulin resistance and diabetes mellitus in HIV-infected children and young adults is needed in order to avoid the associated long-term complications that would otherwise occur, given the improvement in life expectancy of HIV-infected individuals.

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