Multiplecyp51A-Based Mechanisms Identified in Azole-Resistant Isolates of Aspergillus fumigatus from China
2015 ◽
Vol 59
(7)
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pp. 4321-4325
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Keyword(s):
ABSTRACTSeventy-twoA. fumigatusclinical isolates from China were investigated for azole resistance based on mutations ofcyp51A. We identified four azole-resistant strains, among which we found three strains highly resistant to itraconazole, two of which exhibit the TR34/L98H/S297T/F495I mutation, while one carries only the TR34/L98H mutation. To our knowledge, the latter has not been found previously in China. The fourth multiazole-resistant isolate (with only moderate itraconazole resistance) carries a new G432A mutation.
2015 ◽
Vol 60
(1)
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pp. 682-685
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Keyword(s):
2016 ◽
Vol 60
(10)
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pp. 5878-5884
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2013 ◽
Vol 57
(11)
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pp. 5778-5780
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Keyword(s):
2012 ◽
Vol 56
(7)
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pp. 3905-3910
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Keyword(s):
2015 ◽
Vol 53
(3)
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pp. 868-874
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Keyword(s):
2011 ◽
Vol 56
(1)
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pp. 10-16
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