scholarly journals Modeling In Vivo Pharmacokinetics and Pharmacodynamics of Moxifloxacin Therapy for Mycobacterium tuberculosis Infection by Using a Novel Cartridge System

2005 ◽  
Vol 49 (2) ◽  
pp. 853-856 ◽  
Author(s):  
Amy Sarah Ginsburg ◽  
Jin Lee ◽  
Samuel C. Woolwine ◽  
Jacques H. Grosset ◽  
Fayez M. Hamzeh ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Tuberculosis Infection ◽  
Robust Method ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Mycobacterium Tuberculosis Infection ◽  
Antituberculosis Chemotherapy ◽  
In Vivo Pharmacokinetics

ABSTRACT To study the efficacy of moxifloxacin treatment for tuberculosis, we utilized a novel cartridge system to simulate in vivo pharmacokinetics. We found this system to be a robust method for modeling in vivo pharmacokinetics and present data supporting the utility of intermittent moxifloxacin treatment as a component of antituberculosis chemotherapy.

scholarly journals In vivo γδ T Cell Priming to Mycobacterial Antigens by Primary Mycobacterium tuberculosis Infection and Exposure to Nonpeptidic Ligands

1999 ◽  
Vol 5 (7) ◽  
pp. 471-476 ◽  
Author(s):  
Fabrizio Poccia ◽  
Miroslav Malkovsky ◽  
Aaron Pollak ◽  
Vittorio Colizzi ◽  
Guido Sireci ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
T Cell ◽  
Tuberculosis Infection ◽  
Γδ T Cell ◽  
Mycobacterium Tuberculosis Infection ◽  
T Cell Priming ◽  
Mycobacterial Antigens

scholarly journals In vivo expression of innate immunity markers in patients with mycobacterium tuberculosis infection

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Pantelis Constantoulakis ◽  
Eftihia Filiou ◽  
Nikoletta Rovina ◽  
George Chras ◽  
Aggeliki Hamhougia ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Mycobacterium Tuberculosis ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
In Vivo Expression

Lysophosphatidic acid enhances antimycobacterial response during in vivo primary Mycobacterium tuberculosis infection

2011 ◽  
Vol 271 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Giovanni Delogu ◽  
Michela Sali ◽  
Stefano Rocca ◽  
Gianluca Quintiliani ◽  
Marilina B. Santucci ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Lysophosphatidic Acid ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection

scholarly journals In Vivo Biosynthesis of Terpene Nucleosides Provides Unique Chemical Markers of Mycobacterium tuberculosis Infection

2015 ◽  
Vol 22 (4) ◽  
pp. 516-526 ◽  
Author(s):  
David C. Young ◽  
Emilie Layre ◽  
Shih-Jung Pan ◽  
Asa Tapley ◽  
John Adamson ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Tuberculosis Infection ◽  
Chemical Markers ◽  
Mycobacterium Tuberculosis Infection ◽  
Unique Chemical
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