Unique Temperature-Sensitive Defect in Vaccinia Virus Morphogenesis Maps to a Single Nucleotide Substitution in the A30L Gene
2001 ◽
Vol 75
(22)
◽
pp. 11222-11226
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Keyword(s):
ABSTRACT Marker rescue experiments demonstrated that the genetic lesion of a previously isolated vaccinia virus temperature-sensitive mutant which forms multilayered envelope structures with lucent interiors and foci of viroplasm with dense centers mapped to the A30L open reading frame. A single base change, resulting in a nonconservative Ser-to-Phe substitution at residue 17, was associated with degradation of the A30L protein at elevated temperatures.
2003 ◽
Vol 77
(12)
◽
pp. 6799-6810
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2004 ◽
Vol 78
(1)
◽
pp. 257-265
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Keyword(s):
2005 ◽
Vol 79
(13)
◽
pp. 8046-8056
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Keyword(s):
1993 ◽
Vol 67
(5)
◽
pp. 2689-2698
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Keyword(s):
2021 ◽
Keyword(s):
1995 ◽
Vol 69
(10)
◽
pp. 6376-6388
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