scholarly journals Mouse and Drosophila genes encoding the major heat shock protein (hsp70) are highly conserved.

1983 ◽  
Vol 3 (8) ◽  
pp. 1540-1543 ◽  
Author(s):  
D G Lowe ◽  
W D Fulford ◽  
L A Moran
Keyword(s):  
Drosophila Melanogaster ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Hsp70 Gene ◽  
Genes Encoding ◽  
Heat Shock Protein Hsp70

We used a cloned Drosophila melanogaster hsp70 gene to hybrid-select heat shock-induced mouse mRNA and showed that this mRNA encodes the major mouse heat shock protein. This result suggests that the sequence of the hsp70 gene(s) is highly conserved.

Mouse and Drosophila genes encoding the major heat shock protein (hsp70) are highly conserved

1983 ◽  
Vol 3 (8) ◽  
pp. 1540-1543
Author(s):  
D G Lowe ◽  
W D Fulford ◽  
L A Moran
Keyword(s):  
Drosophila Melanogaster ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Hsp70 Gene ◽  
Genes Encoding ◽  
Heat Shock Protein Hsp70

We used a cloned Drosophila melanogaster hsp70 gene to hybrid-select heat shock-induced mouse mRNA and showed that this mRNA encodes the major mouse heat shock protein. This result suggests that the sequence of the hsp70 gene(s) is highly conserved.

Restriction fragment length polymorphisms at the heat shock protein HSP70 gene(s) in pigs*

2009 ◽  
Vol 24 (1) ◽  
pp. 67-68 ◽  
Author(s):  
M K Ruohonen-Lehto ◽  
M F Rothschild ◽  
R G Larson ◽  
M K Ruohonen-Lehto ◽  
M F Rothschild ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Restriction Fragment ◽  
Fragment Length ◽  
Restriction Fragment Length Polymorphisms ◽  
Hsp70 Gene ◽  
Length Polymorphisms ◽  
Heat Shock Protein Hsp70 ◽  
Restriction Fragment Length

scholarly journals Compound A, a Selective Glucocorticoid Receptor Modulator, Enhances Heat Shock Protein Hsp70 Gene Promoter Activation

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69115 ◽  
Author(s):  
Ilse M. Beck ◽  
Zuzanna J. Drebert ◽  
Ruben Hoya-Arias ◽  
Ali A. Bahar ◽  
Michael Devos ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Glucocorticoid Receptor ◽  
Gene Promoter ◽  
Hsp70 Gene ◽  
Promoter Activation ◽  
Compound A ◽  
Receptor Modulator ◽  
Heat Shock Protein Hsp70

scholarly journals Structure and expression of the human gene encoding major heat shock protein HSP70.

1985 ◽  
Vol 5 (2) ◽  
pp. 330-341 ◽  
Author(s):  
B Wu ◽  
C Hunt ◽  
R Morimoto
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Genomic Library ◽  
Human Gene ◽  
Chimeric Gene ◽  
Hsp70 Gene ◽  
Gene Encoding ◽  
Hsp70 Mrna ◽  
Flanking Sequences ◽  
Heat Shock Protein Hsp70

We have cloned a human gene encoding the 70,000-dalton heat shock protein (HSP70) from a human genomic library, using the Drosophila HSP70 gene as a heterologous hybridization probe. The human recombinant clone hybridized to a 2.6-kilobase polyadenylated mRNA from HeLa cells exposed to 43 degrees C for 2 h. The 2.6-kilobase mRNA was shown to direct the translation in vitro of a 70,000-dalton protein similar in electrophoretic mobility to the HSP70 synthesized in vivo. From the analysis of S1 nuclease-resistant mRNA-DNA hybrids, the HSP70 gene appears to be transcribed as an uninterrupted mRNA of 2.3 kilobases. We show that the cloned HSP70 gene contains the sequences necessary for heat shock-induced expression by two criteria. First, hamster cells transfected with a subclone containing the HSP70 gene and flanking sequences synthesized a HSP70-like protein upon heat shock. Second, human cells transfected with a chimeric gene containing the 5' flanking sequences of the HSP70 gene and the coding sequences of the bacterial chloramphenicol acetyltransferase gene transcribed the chimeric gene upon heat shock. We show that the HSP70 mRNA transcribed in an adenovirus 5 transformed human cell line (293 cells) is identical to the HSP70 mRNA induced by heat shock.

Differential diagnosis of oocysts of Hammondia-like organisms of dogs and cats by PCR-RFLP analysis of 70-kilodalton heat shock protein (HSP70) gene

2008 ◽  
Vol 103 (1) ◽  
pp. 235-238 ◽  
Author(s):  
Renata Molina Monteiro ◽  
Hilda Fátima de Jesus Pena ◽  
Solange Maria Gennari ◽  
Sheila Oliveira de Souza ◽  
Leonardo José Richtzenhain ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Rflp Analysis ◽  
Hsp70 Gene ◽  
Pcr Rflp ◽  
Heat Shock Protein Hsp70
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