Morphological and functional abnormalities in neuromuscular junctions of Drosophila melanogaster induced by human APP gene expression

2012 ◽  
Vol 6 (4) ◽  
pp. 326-334 ◽  
Author(s):  
S. V. Sarantseva ◽  
G. A. Kislik ◽  
N. A. Tkachenko ◽  
A. N. Vasiliev ◽  
A. L. Schwarzman
2006 ◽  
Vol 22 (06) ◽  
Author(s):  
Aleid Ruijs ◽  
Tateki Kubo ◽  
Jae Song ◽  
Milan Ranka ◽  
Mark Randolph ◽  
...  

2013 ◽  
Vol 304 (3) ◽  
pp. R177-R188 ◽  
Author(s):  
Wendi S. Neckameyer ◽  
Kathryn J. Argue

Numerous studies have detailed the extensive conservation of developmental signaling pathways between the model system, Drosophila melanogaster, and mammalian models, but researchers have also profited from the unique and highly tractable genetic tools available in this system to address critical questions in physiology. In this review, we have described contributions that Drosophila researchers have made to mathematical dynamics of pattern formation, cardiac pathologies, the way in which pain circuits are integrated to elicit responses from sensation, as well as the ways in which gene expression can modulate diverse behaviors and shed light on human cognitive disorders. The broad and diverse array of contributions from Drosophila underscore its translational relevance to modeling human disease.


Cell ◽  
1982 ◽  
Vol 28 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Elizabeth C. Raff ◽  
Margaret T. Fuller ◽  
Thomas C. Kaufman ◽  
Kenneth J. Kemphues ◽  
Jane E. Rudolph ◽  
...  

2015 ◽  
Vol 5 (12) ◽  
pp. 2843-2856 ◽  
Author(s):  
Florence Gutzwiller ◽  
Catarina R. Carmo ◽  
Danny E. Miller ◽  
Danny W. Rice ◽  
Irene L. G. Newton ◽  
...  

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