In the present work, surface treatment of surgical implant Titanium alloy with micro
bioactive nanotube was experimented. Surface treatment of Ti-6Al-4V bio-implant carried out by
giving alkali hydrothermal and heat treatment. The specimens were treated in 1M NaOH at 100, 150,
200°C for different holding time of 2 hr, 4 hr, 6hr, 12 hr, 24hr & 48 hr. The hydrogel layer generated
during the alkali treatment was crystallized to sodium titanate (Na2Ti6O13) and resulted into the
formation of nano sized tubes on heat treatment. X-ray Diffractrometry (XRD), Scanning Electron
Microscopy (SEM) and Transmission Electron Microscopy (TEM) revealed the different phases and
surface morphology of these nanorods. The biocompatibility test done using Simulate Body Fluid
(SBF) showed that the Hydroxyapatite (HAp) was well formed at the sodium titanate nanotube layer
generated on the Ti-6Al-4V specimen. The best condition for this increase in surface
biocompatibility was optimized to 6 hours hydrothermal treatment under 200°C using 1 M NaOH
followed by 1 hour heat treatment at 600°C.