Role of systemic steroids in acute preschool wheeze

2010 ◽  
Vol 95 (7) ◽  
pp. 491-492 ◽  
Author(s):  
J. Grigg
Keyword(s):  
Systemic Steroids

scholarly journals Long-term visual outcomes of endophthalmitis and the role of systemic steroids in addition to intravitreal dexamethasone

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Christopher D. Conrady ◽  
Richard M. Feist ◽  
Albert T. Vitale ◽  
Akbar Shakoor
Keyword(s):  
Systemic Steroids ◽  
Visual Outcomes ◽  
Intravitreal Dexamethasone

scholarly journals The Role of Systemic Steroids in Postintubation Tracheal Stenosis: A Randomized Clinical Trial

2017 ◽  
Vol 103 (1) ◽  
pp. 246-253 ◽  
Author(s):  
Mohammad Behgam Shadmehr ◽  
Azizollah Abbasidezfouli ◽  
Roya Farzanegan ◽  
Saviz Pejhan ◽  
Abolghasem Daneshvar Kakhaki ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Tracheal Stenosis ◽  
Systemic Steroids

The role of systemic steroids and phototherapy in the treatment of stable vitiligo: a randomized controlled trial

2016 ◽  
Vol 29 (6) ◽  
pp. 406-412 ◽  
Author(s):  
Medhat El Mofty ◽  
Samia Essmat ◽  
Randa Youssef ◽  
Sherine Sobeih ◽  
Doaa Mahgoub ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Systemic Steroids ◽  
Randomized Controlled

scholarly journals Role of systemic steroids in acute hemorrhagic edema of infancy: report of two cases

2019 ◽  
Vol 6 (2) ◽  
pp. 537
Author(s):  
Mohammed S. Alharbi
Keyword(s):  
Clinical Presentation ◽  
Leukocytoclastic Vasculitis ◽  
Skin Lesions ◽  
Histological Evaluation ◽  
Conservative Approach ◽  
Systemic Steroids ◽  
Unusual Form ◽  
Clinical Cases

Acute hemorrhagic edema of infancy (AHEI) is an unusual form of leukocytoclastic vasculitis with dramatic distinguishing skin lesions that occurs in infants who age 4 to 24 months old. Clinical presentation at onset requires clinical and, less often, histological evaluation to distinguish it from more serious diseases and other vasculitis. Treatment of AHEI remains controversial; and since it is a self-limiting disease, a conservative approach should be considered first. Although some authors have reported that the use of steroids may be beneficial if started early on, we think their use, based on our presented cases here, may accelerate the healing and improves the color of preexisting skin lesions but does not significantly alter the course of the disease. Authors reported here two clinical Cases of AHEI (Diagnosed based on characteristic skin lesions and confirmed with Histological evaluation) who were treated initially with systemic steroids, besides we reviewed the role of systemic steroids in the treatment of AHEI.

Predictors of Avascular Necrosis (AVN) of Bone after Long-Term Follow-Up of Allogeneic and Autologous Hematopoietic Cell Transplantation (HCT) for Malignant and Non-Malignant Disorders.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 700-700
Author(s):  
Liton Francisco ◽  
Stephanie Campbell ◽  
Andrea Carter ◽  
Roberto Rodriguez ◽  
Joseph Rosenthal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Genetic Susceptibility ◽  
Cumulative Incidence ◽  
Systemic Steroids ◽  
Allogeneic Hct ◽  
Populations At Risk ◽  
Increased Risk ◽  
Autologous Hct

Abstract Patients undergoing allogeneic HCT are known to be at an increased risk of AVN. Chronic steroid use, to treat chronic graft vs. host disease (cGVHD) has been identified as a risk factor. Previous studies reporting AVN after allogeneic HCT are limited either due to small cohort size or reliance on registry data for passive reporting on outcomes such as AVN. Furthermore, little is known about the risk of AVN after autologous HCT. We report a retrospective chart review of 1595 consecutive patients undergoing HCT at City of Hope Cancer Center between 1976 and 1998, and surviving one or more years after HCT. The median age at HCT was 35 years (range, 0.6–71.5) and the median length of follow-up was 7.0 years (1–25.3). The cohort included 940 males (59%). In this cohort, 78 patients developed AVN of 163 joints, resulting in a mean of 2.1 affected joints per patient (range, 1 to 8). Diagnosis of AVN was confirmed by review of radiologic evidence of necrosis in the presence of clinical symptoms. The hip joint was the most common joint affected (70.5% of patients), followed by the knee (35%) and shoulder (26%). Symptoms developed a median of 38.7 months from HCT (12 to 199 months). The overall cumulative incidence was 6.2% at 15 years from HCT for the first reported AVN developing one or more years after HCT. Nineteen of 741 autologous HCT survivors developed AVN (cumulative incidence: 3.5% at 10 years), while 46 of the 746 allogeneic sibling donor HCT survivors (cumulative incidence, 6.2% at 10 years), and 12 of the 108 unrelated donor HCT recipients developed AVN (cumulative incidence 13.9% at 10 years, p<0.001). A multivariate analysis of the entire cohort identified exposure to cyclosporine, both for GVHD prophylaxis (relative risk (RR), 3.03, 95% confidence interval (CI), 1.4–6.5), and treatment of cGVHD (RR=4.1, 95% CI, 2.2–7.9), male sex (RR=2.1, 95% CI, 1.3–3.6), primary diagnosis of multiple myeloma (RR=7.5, 95% CI, 1.4–40.7) and Hodgkin disease (RR=10.8, 95% CI, 2.2–53.6) when compared with aplastic anemia to be independently associated with an increased risk of AVN after HCT. Among survivors of allogeneic HCT, presence of cGVHD (RR=4.2, 95% CI, 1.7–10.0), and treatment of cGVHD with a combination of systemic steroids, Cyclosporin, and Tacrolimus (RR=3.6, 95% CI, 1.7–7.7), compared to a combination of systemic steroids and Cyclosporin, were independently associated with an increased risk of AVN. Finally, no risk factors were identified for the development of AVN among autologous HCT recipients. AVN is a frequent and significantly debilitating consequence of HCT, frequently requiring surgical intervention, and potentially impacting the overall HRQL of the HCT survivors. This study describes the magnitude of risk in autologous and allogeneic HCT recipients and identifies cGVHD and use of immunosuppressive agents such as systemic steroids, Cyclosporin and Tacrolimus as risk factors, indicating the possible pathogenic role of Cyclosporin- and Tacrolimus-induced microangiopathy in the development of AVN in this population. Identification of genetic susceptibility and the role of interaction between therapeutic exposures and genetic susceptibility in handling these therapeutic exposures would further assist in identification of the populations at risk and the mechanistic pathways involved in the development of AVN in this population.

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1005-1009 ◽  
Author(s):  
D. J. Fernbach
Keyword(s):  
Wilms Tumor

Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽  
1966 ◽  
Vol 195 (3) ◽  
pp. 167-172 ◽  
Author(s):  
T. E. Van Metre
Keyword(s):  
Diagnosis And Management

The power of norms to sway fused group members

2018 ◽  
Vol 41 ◽  
Author(s):  
Winnifred R. Louis ◽  
Craig McGarty ◽  
Emma F. Thomas ◽  
Catherine E. Amiot ◽  
Fathali M. Moghaddam
Keyword(s):  
Evolutionary Anthropology ◽  
Normative Systems ◽  
Violent Extremism ◽  
Identity Fusion ◽  
Group Members

AbstractWhitehouse adapts insights from evolutionary anthropology to interpret extreme self-sacrifice through the concept of identity fusion. The model neglects the role of normative systems in shaping behaviors, especially in relation to violent extremism. In peaceful groups, increasing fusion will actually decrease extremism. Groups collectively appraise threats and opportunities, actively debate action options, and rarely choose violence toward self or others.

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