scholarly journals The application of naive Bayes model averaging to predict Alzheimer's disease from genome-wide data

2011 ◽  
Vol 18 (4) ◽  
pp. 370-375 ◽  
Author(s):  
Wei Wei ◽  
Shyam Visweswaran ◽  
Gregory F Cooper
2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Fayroz F. Sherif ◽  
Nourhan Zayed ◽  
Mahmoud Fakhr

Single nucleotide polymorphisms (SNPs) contribute most of the genetic variation to the human genome. SNPs associate with many complex and common diseases like Alzheimer’s disease (AD). Discovering SNP biomarkers at different loci can improve early diagnosis and treatment of these diseases. Bayesian network provides a comprehensible and modular framework for representing interactions between genes or single SNPs. Here, different Bayesian network structure learning algorithms have been applied in whole genome sequencing (WGS) data for detecting the causal AD SNPs and gene-SNP interactions. We focused on polymorphisms in the top ten genes associated with AD and identified by genome-wide association (GWA) studies. New SNP biomarkers were observed to be significantly associated with Alzheimer’s disease. These SNPs are rs7530069, rs113464261, rs114506298, rs73504429, rs7929589, rs76306710, and rs668134. The obtained results demonstrated the effectiveness of using BN for identifying AD causal SNPs with acceptable accuracy. The results guarantee that the SNP set detected by Markov blanket based methods has a strong association with AD disease and achieves better performance than both naïve Bayes and tree augmented naïve Bayes. Minimal augmented Markov blanket reaches accuracy of 66.13% and sensitivity of 88.87% versus 61.58% and 59.43% in naïve Bayes, respectively.


2012 ◽  
Vol 6-7 ◽  
pp. 576-582
Author(s):  
Ping Li ◽  
Ming Liang Cui ◽  
Zhen Shan Hou ◽  
Liu Liu Wei ◽  
Wen Hao Ying ◽  
...  

Session segmentation can not only contribute a lot to the further and deeper analysis of user’s search behavior but also act as the foundation of other retrieval process researches based on users’ complicated search behaviors. This paper proposes a session boundary discrimination model utilizing time interval and query likelihood on the basis of Naive Bayes Model. Compared with previous study, the model proposed in this paper shows a prominent improvement through experiment in three aspects, which is: recall ratio, precision ratio and value F. Owing to its advantage in session boundary discrimination, the application of the model can serve as a tool in fields like personalized information retrieval, query suggestion, search activity analysis and other fields which is related to search results improvement.


IEEE Access ◽  
2020 ◽  
Vol 8 ◽  
pp. 217917-217927
Author(s):  
Dashe Li ◽  
Jiajun Sun ◽  
Huanhai Yang ◽  
Xueying Wang

2020 ◽  
Vol 541 ◽  
pp. 316-331
Author(s):  
Si-Yuan Liu ◽  
Jing Xiao ◽  
Xiao-Ke Xu

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Mengmeng Wang ◽  
Wanli Zuo ◽  
Ying Wang

Today microblogging has increasingly become a means of information diffusion via user’s retweeting behavior. Since retweeting content, as context information of microblogging, is an understanding of microblogging, hence, user’s retweeting sentiment tendency analysis has gradually become a hot research topic. Targeted at online microblogging, a dynamic social network, we investigate how to exploit dynamic retweeting sentiment features in retweeting sentiment tendency analysis. On the basis of time series of user’s network structure information and published text information, we first model dynamic retweeting sentiment features. Then we build Naïve Bayes models from profile-, relationship-, and emotion-based dimensions, respectively. Finally, we build a multilayer Naïve Bayes model based on multidimensional Naïve Bayes models to analyze user’s retweeting sentiment tendency towards a microblog. Experiments on real-world dataset demonstrate the effectiveness of the proposed framework. Further experiments are conducted to understand the importance of dynamic retweeting sentiment features and temporal information in retweeting sentiment tendency analysis. What is more, we provide a new train of thought for retweeting sentiment tendency analysis in dynamic social networks.


2012 ◽  
Vol 19B (3) ◽  
pp. 195-200
Author(s):  
Jae-Hoon Kim ◽  
Kil-Ho Jeon

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 57868-57880 ◽  
Author(s):  
Longjie Li ◽  
Shijin Xu ◽  
Mingwei Leng ◽  
Shiyu Fang ◽  
Xiaoyun Chen

Author(s):  
Neeraj Saxena ◽  
Ruiyang Wang ◽  
Vinayak V. Dixit ◽  
S. Travis Waller

Driving in congested traffic is a nuisance that not only results in longer travel times, but also triggers frustration and impatience among drivers. A few studies have modeled the effects of congested traffic in the resulting route choice behavior of car drivers. The studies used frequentist models such as discrete choice models to analyze large samples. However, these studies did not compare the inferences obtained from the frequentist and Bayesian approaches, particularly for datasets which are not sufficiently large. It has been shown by researchers that Bayesian models perform well, especially when the sample size is small. Thus, this paper develops and compares a multinomial logit (frequentist) and a Naïve Bayes (Bayesian) model on a mid-sized dataset of size around 100 participants which was obtained from a driving simulator experiment to understand driver’s route choice under stop-and-go traffic. The results show that the prediction power of the Naïve Bayes model is much higher than the multinomial logit model (MNL). The Naïve Bayes model is also found to perform better than machine learning algorithms like the decision tree model. The findings from this study will be useful to researchers and practitioners as they should test both the approaches and select the appropriate model, particularly in the case of seemingly large datasets.


Author(s):  
Patrick N. Mwaro ◽  
Dr. Kennedy Ogada ◽  
Prof. Wilson Cheruiyot

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