scholarly journals PS-042c Is Low-dose Combined Oral Contraceptives Use Associated To Lower Bone Mineral Content Variation In Adolescents Over A One-year Period?

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A127.1-A127
Author(s):  
TB Goldberg ◽  
TP Biason ◽  
CS Kurokawa ◽  
MR Moretto ◽  
AS Teixeira ◽  
...  
2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Talita Poli Biason ◽  
Tamara Beres Lederer Goldberg ◽  
Cilmery Suemi Kurokawa ◽  
Maria Regina Moretto ◽  
Altamir Santos Teixeira ◽  
...  

1996 ◽  
Vol 82 (1) ◽  
pp. 65-67 ◽  
Author(s):  
Sandro Barni ◽  
Paolo Lissoni ◽  
Gabriele Tancini ◽  
Antonio Ardizzoia ◽  
Marina Cazzaniga

In this study, the authors have analyzed the possible effects of one-year adjuvant treatment with tamoxifen on bone mineral density in postmenopausal breast cancer women. Bone mineral content was studied by photon absorptiometry (I-125), whereas bone balance was analyzed indirectly by serum PTH, osteocalcin, calcitonin, calcium and alkaline phosphatase levels. Bone mineral content and serum bone-related substances were measured before starting treatment and after one year. Results were analyzed using Student's t test for paired data. No difference was found between the two measurements for bone mineral content, PTH, calcitonin, calcium and alkaline phosphatase levels. Measurements at entry and after one year of treatment showed a statistically significant difference ( P < 0.001) only for osteocalcin. In accordance with other authors, we can conclude that treatment with tamoxifen does not cause an increase in menopausal bone resorption. The finding that osteocalcin levels decreased after one year of therapy with tamoxifen is interesting, but further studies are necessary to clarify the role of such levels in predicting a turnover of bone balance towards osteoblastic activity.


2013 ◽  
Vol 52 (2) ◽  
pp. S92
Author(s):  
Talita Poli Biason ◽  
Maria Regina Moretto ◽  
Cristina Fortes Rezende ◽  
Cilmery Suemi Kurokawa ◽  
Altamir Teixeira ◽  
...  

1991 ◽  
Vol 35 (3-4) ◽  
pp. 142-145 ◽  
Author(s):  
Liliana N. Contreras ◽  
L. Rizzo ◽  
R.M. G&oacute;mez ◽  
J.R. Zanchettal ◽  
Maria A. Rossi ◽  
...  

1990 ◽  
Vol 123 (1) ◽  
pp. 14-18 ◽  
Author(s):  
H. Resch ◽  
P. Pietschmann ◽  
E. Krexner ◽  
W. Woloszczuk ◽  
R. Willvonseder

Abstract. A double-blind, placebo-controlled study on 31 patients with osteoporotic spine fractures was performed in order to assess the effects of one-year cyclical estrogen/gestagen replacement therapy (Trisequens, Novo) on peripheral bone mineral content and bone turnover. Bone mineral content was measured by single-photon absorptiometry with 125I before, and 6 and 12 months after start of therapy. Calcium, phosphate, alkaline phosphatase, parathyroid hormone, calcidiol, calcitonin and 2-hour urinary hydroxyproline excretion were measured to evaluate bone turnover. After 12 months, forearm bone mineral content showed a significant increase (p<0.02) in the treatment group, whereas in the control group no statistically significant change in peripheral bone mass was observed. Parameters of bone metabolism showed a decrease in hydroxyproline excretion (p<0.02) as well as alkaline phosphatase (p<0.01) and no changes in parathyroid hormone, calcidiol, and calcitonin. These results demonstrate that one-year cyclical estrogen/gestagen replacement therapy improves peripheral bone mineral content measured by single-photon absorptiometry. This effect appears to be induced by an inhibition of bone resorption.


Sign in / Sign up

Export Citation Format

Share Document