scholarly journals Methotrexate treatment in juvenile idiopathic arthritis: when is the right time to stop?

2004 ◽  
Vol 63 (2) ◽  
pp. 206-208 ◽  
Author(s):  
D Foell
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Methotrexate Treatment ◽  
The Right

Deficits of vitamin D are strongly associated with methotrexate treatment in patients with juvenile idiopathic arthritis

2015 ◽  
Author(s):  
Adrian Goralczyk ◽  
Jerzy Konstantynowicz ◽  
Pawel Abramowicz ◽  
Elzbieta Dobrenko ◽  
Edyta Babinska-Malec
Keyword(s):  
Vitamin D ◽  
Juvenile Idiopathic Arthritis ◽  
Methotrexate Treatment

Relapse Rate of Uveitis Post-Methotrexate Treatment in Juvenile Idiopathic Arthritis

2011 ◽  
Vol 151 (2) ◽  
pp. 217-222 ◽  
Author(s):  
Viera Kalinina Ayuso ◽  
Evelyne Leonce van de Winkel ◽  
Aniki Rothova ◽  
Joke Helena de Boer
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Relapse Rate ◽  
Methotrexate Treatment

Mandibular Condyle Lesions in Children with Juvenile Idiopathic Arthritis

2008 ◽  
Vol 45 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Sossani Sidiropoulou-Chatzigianni ◽  
Moschos A. Papadopoulos ◽  
George Kolokithas
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Statistical Evaluation ◽  
Mandibular Condyle ◽  
Chi Square ◽  
Temporomandibular Joints ◽  
Student’S T ◽  
The Right ◽  
Bilateral Lesions ◽  
Bilateral Destruction ◽  
Student’S T Test

Objective: To assess the prevalence of radiographically detectable destruction of the temporomandibular joints in children with juvenile idiopathic arthritis and to study the possible relationships between condylar destruction and type and duration of the disease, as well as the type of occlusion. Material And Method: The study group consisted of 66 children with juvenile idiopathic arthritis (27 boys, 39 girls; mean age, 11.9 years). The possible presence of condylar destruction was examined in panoramic radiographs. The medical history and the type of malocclusion were registered also. The statistical evaluation was performed by means of descriptive statistics, Student's t test, Pearson's chi-square, and an analysis of variance test. The whole procedure was repeated after a 4-week interval to estimate the error of the method. Results: Of the children with juvenile idiopathic arthritis, 50% showed some form of condylar destruction. Significant correlation was found between the type of the disease and the condyles affected. In the polyarticular type of juvenile idiopathic arthritis, 75% of the children presented affected condyles and 55.6% of them showed lesions bilaterally. The condylar affection was found to be independent of sex, although girls showed a tendency to bilateral lesions. In children with unilateral destruction, the right condyle was affected four times more frequently than the left. The duration of juvenile idiopathic arthritis seems to be significantly correlated to condylar destruction and especially to bilateral destruction. Conclusion: Children with juvenile idiopathic arthritis presented a remarkable prevalence of condylar destruction, which was correlated to the type and duration of the disease.

scholarly journals Reasons for stopping methotrexate treatment in patients with juvenile idiopathic arthritis

2014 ◽  
Vol 12 (Suppl 1) ◽  
pp. P199
Author(s):  
Ana Carolina Da Silva ◽  
A Farias ◽  
Nailu Sinicato ◽  
R Veloso ◽  
Roberto Marini ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Methotrexate Treatment

Intraocular schwannoma with extrascleral extension

2020 ◽  
pp. 112067212092021
Author(s):  
Sanika Udyaver ◽  
Li-Anne S Lim ◽  
Tatyana Milman ◽  
Arman Mashayekhi ◽  
Jerry A Shields ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Anterior Segment ◽  
Subretinal Fluid ◽  
Ultrasound Biomicroscopy ◽  
Orange Pigment ◽  
Neoplastic Processes ◽  
Benign Schwannoma ◽  
S 100 ◽  
History Of ◽  
The Right

Purpose To report a rare case of intraocular schwannoma with extrascleral extension in a patient with juvenile idiopathic arthritis and to review the literature for this topic. Methods Case report. Results A 19-year-old male with a history of juvenile idiopathic arthritis was referred for diagnosis and management of an episcleral mass, initially thought to be focal nodular scleritis. The ocular surface of the right eye revealed an elevated amelanotic episcleral nodule inferonasally, with thin strands of overlying sclera, feeding episcleral vessels, and measuring 11 mm × 11 mm in diameter and 5 mm in thickness. Ophthalmoscopic examination revealed a minimally pigmented ciliochoroidal tumor measuring 13 mm in diameter and 11.4 mm in total thickness and without associated subretinal fluid, orange pigment, or drusen. Ultrasound biomicroscopy and anterior-segment optical coherence tomography confirmed a solid mass with scleral disruption and extraocular extension. Shave biopsy revealed palisading spindle cells and interspersed eosinophilic fibrillary cytoplasmic processes, forming Verocay bodies. The specimen stained positive for S-100 and negative for Melan-A, consistent with benign schwannoma. Observation was recommended. Conclusion Intraocular schwannoma is a rare, benign uveal tumor that can demonstrate extrascleral extension, mimicking inflammatory and malignant neoplastic processes. Clinical diagnosis is challenging, and tissue biopsy is required for definite diagnosis.

P095 Camptodactyly, arthropathy, coxa-vara, pericarditis syndrome: a case report

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
A Ferhat ◽  
F Mechid ◽  
A Rahmoune ◽  
M A Ifticene ◽  
R Benaziez ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Genetic Disorder ◽  
Cardiac Monitoring ◽  
Coxa Vara ◽  
Inflammatory Arthropathy ◽  
The Family ◽  
History Of ◽  
Chronic Arthropathy ◽  
The Right ◽  
Inflammatory Syndrome

Abstract Background Camptodactyly, arthropathy, coxa vara, pericarditis (CACP) syndrome is a rare genetic disorder with autosomal recessive transmission including camptodactyly, synovial hyperplasia-related arthropathy, progressive coxa vara deformity and non-inflammatory pericarditis. We report the observation of a case. Observation S.Y aged 8.5 years, from a consanguineous marriage, presented with a chronic arthropathy affecting wrists, knees and ankles that had been evolving for 6 years and currently, elbows are also affected. The history includes surgery for claw deformity of the hands at the age of 3. No similar cases in the family. Osteoarticular examination showed symmetrical swelling of the elbows, wrists (Fig. 1),knees (Fig. 2) and ankles (Fig. 3.The affected joints were neither red, painful nor warm on palpation, with normal mobility. The onset of symptoms could not be determined due to the indolence of the condition and the rest of the clinical examination was unremarkable. Discussion CACP syndrome is a more common condition in the Middle East and North Africa, with about 20 cases reported worldwide. This syndrome is still poorly understood and is often confused with juvenile idiopathic arthritis. It should be suspected in the presence of any congenital claw deformity of the hands (camptodactyly) with a chronic non-inflammatory arthropathy, which are constant signs. Coxa-vara and pericarditis (found respectively in 60 and 30% of cases) should be systematically sought. The consanguinity reported in the literature is also present in our case. However, there are no similar cases in siblings. The diagnosis is important, thus avoiding the initiation of unnecessary treatments such as corticosteroids, DMARDs or biotherapy. Biology no inflammatory syndrome, FAN negatives. Standard X-ray of the pelvis presence of a coxa-vara on the right Joint ultrasound common tenosynovitis of the extensors of the fingers, effusion with synovial hypertrophy without a Doppler catch of the elbows, knees and ankles Myelogram without abnormality. Cardiac ultrasound without pericarditis. The diagnosis of CACP was made in view of: a history of camptodactyly, chronic non-inflammatory arthropathy and coxa-vara. Analgesic treatment was instituted in case of pain, with cardiac monitoring by ultrasound every 6 months. Conclusion CACP syndrome is a rare disease often confused with juvenile idiopathic arthritis. Congenital camptodactyly and non-inflammatory arthropathy are very evocative of the diagnosis. The absence of similar cases in siblings makes our observation special.

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