scholarly journals Male occult triple-negative breast cancer

2019 ◽  
Vol 12 (4) ◽  
pp. e229482
Author(s):  
Basma Alsayed ◽  
Hussain Adnan Abdulla ◽  
Hadi Alaskar ◽  
Ali Dhaif
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Breast Lesion ◽  
Triple Negative ◽  
Radical Mastectomy ◽  
Male Breast ◽  
Modified Radical Mastectomy ◽  
Important Condition ◽  
Axillary Metastases ◽  
Rare Type

Male breast cancer is a rare but important condition accounting for only 1% of breast cancer worldwide and less than 1% of all male malignancies. Occult male breast cancer is an extremely rare type of male breast cancer that manifests as axillary metastases without an identifiable breast lesion. We report a case of triple-negative occult male breast cancer who underwent modified radical mastectomy.

scholarly journals Management and Outcomes of Male Breast Cancer in Zaria, Nigeria

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Adamu Ahmed ◽  
Yahaya Ukwenya ◽  
Adamu Abdullahi ◽  
Iliyasu Muhammad
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Advanced Disease ◽  
Radical Mastectomy ◽  
Male Breast ◽  
Tumor Diameter ◽  
Axillary Lymph ◽  
Breast Cancers ◽  
Modified Radical Mastectomy ◽  
Male Patients

Male breast cancer is an uncommon disease accounting for only 1% of all breast cancers. We present the evaluation, treatment and outcome of male patients seen with breast cancer in our institution. Male patients that had histological diagnosis of breast cancer from 2001 to 2010 were retrospectively evaluated. After evaluation patients were treated with modified radical mastectomy. Combination chemotherapy was given to patients with positive axillary lymph nodes. Radiotherapy and hormonal therapy were also employed. There were 57 male patients with breast cancer which accounted for 9% of all breast cancers seen during the study period. Their mean age was 59 ± 2.3 years. The mean tumor diameter was 13 ± 2.5 cm. Fifty three (93%) patients presented with advanced disease including 15 with distant metastasis. Four patients with stage II disease were treated with modified radical mastectomy, chemotherapy and tamoxifen. Of the 30 patients with sage III disease that had modified radical mastectomy, complete axillary clearance and tumor free margins were achieved in 25. Overall 21 (36.8%) patients were tumor free at one year. Overall 5-year survival was 22.8%. In conclusion, male patients with breast cancer present with advanced disease which is associated with poor outcome of treatment.

scholarly journals Modified Radical Mastectomy for Male Breast Cancer

2019 ◽  
Vol 20 ◽  
pp. 1336-1339
Author(s):  
Mahmoud Musa Al Awayshih ◽  
Mohammad Nabih Nofal ◽  
Ali Jad Yousef
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Radical Mastectomy ◽  
Male Breast ◽  
Modified Radical Mastectomy

Triple Negative Male Breast Cancer

2021 ◽  
Vol 47 (2) ◽  
pp. e34
Author(s):  
Qasif Qavi ◽  
Rizwan Ahmed ◽  
Firas Alkistawi ◽  
Omotara Lesi ◽  
Amira Asaad ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Triple Negative ◽  
Male Breast

scholarly journals Immunohistochemistry profile and its relation with prognosis in locally advanced breast cancer

2019 ◽  
Vol 6 (12) ◽  
pp. 4507
Author(s):  
Naseef Kannanavil ◽  
Nabeel Thommil Padinjarenalakath ◽  
Ahsan Vilayapoyilil ◽  
Abidali Karatparambil
Keyword(s):  
Breast Cancer ◽  
Triple Negative ◽  
Locally Advanced ◽  
Radical Mastectomy ◽  
Response To Therapy ◽  
Advanced Breast ◽  
Age Group ◽  
Modified Radical Mastectomy ◽  
Number Of Patients ◽  
Related Mortality

Background: Breast cancer is one of the most common malignancy and leading cause of cancer related deaths in women worldwide. Immunohistochemistry (IHC) is done to characterize intracellular proteins or cell-surface antigens and is used to assess tumour subtypes, confirm diagnosis, predict prognosis and response to therapy. The aim of the present study was to evaluate the relationship of IHC profile- ER, PR and HER2 neu and prognosis of patients who underwent modified radical mastectomy for locally advanced breast cancer.Methods: A retrospective cohort study was conducted at MES Medical College Hospital from October 2015 to November 2017 in patients who underwent modified radical mastectomy for locally advanced breast carcinoma. A total of 65 women were enrolled in the study. 5 years survival was taken as the prognostic indicator.Results: Majority of the patients belong to the age group of 40-49 years with 40% patients followed by 33.84% patients in the age group of 50-59 years. Maximum number of patients was found in 2B stage of tumour. Maximum patients belonged to the ER/PR+, HER2- subgroup (27), followed by triple negative (ER/PR-, HER2) subgroup (16). There was no disease related mortality in ER/PR+, HER2+ and ER/PR+, HER2- subgroups. There were 1 and 2 disease related mortality in ER/PR-, HER2+ and triple negative subgroups respectively.Conclusions: In the present study the worst prognosis was observed in triple negative (ER/PR-,HER2-) IHC subgroup followed by the HER2 enriched (ER/PR-, HER2+) subgroup. 

scholarly journals Occult triple negative male breast cancer. The usefulness of molecular platforms. A case report

2021 ◽  
pp. 100097
Author(s):  
Angelats L ◽  
Estival A ◽  
Martinez-Cardús A ◽  
Musulen E ◽  
Margelí M
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Male Breast Cancer ◽  
Triple Negative ◽  
Male Breast

scholarly journals Rare Case of Male Breast Cancer and Axillary Lymphoma in the Same Patient: An Unique Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Emiliano Sordi ◽  
Katia Cagossi ◽  
Maria Grazia Lazzaretti ◽  
Daniel Gusolfino ◽  
Fabrizio Artioli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Ductal Carcinoma ◽  
Malignant Lesion ◽  
Gene Mutations ◽  
Radical Mastectomy ◽  
Simultaneous Presentation ◽  
Needle Aspiration ◽  
Male Breast ◽  
First Case

Breast cancer in men is uncommon, and even more rare is the simultaneous presentation of two different malignancies. A 39-year-old man was diagnosed with both breast cancer and axillary lymphoma. Familiar history revealed that his mother died because of breast cancer. The patient underwent fine needle aspiration leading to the diagnosis of malignant lesion. Modified radical mastectomy was performed. Histology revealed an infiltrating ductal carcinoma 2.8 cm wide, grade 2, with vascular and lymphatic invasion. Surprisingly, one of the second level nodes was confirmed as a high-grade large B cell non-Hodgkin's lymphoma. No family inheritance or gene mutations (BRCA 1 and 2) were found. The patient underwent local radiotherapy, followed by 6 chemotherapy courses (RCHOP) and treatment with tamoxifen 20 mg/daily. To our knowledge, this is the first case reported in literature of male breast cancer and axillary lymphoma simultaneously confirmed in the same patient.

scholarly journals Male Breast Cancer with Ureteral Metastasis: A Case Report

2020 ◽  
Author(s):  
Chen Yanbo ◽  
Wu Jiannan ◽  
Hu Tingting ◽  
Wang Juanjuan ◽  
Su Fengxi
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Triple Negative ◽  
Genetic Test ◽  
Male Breast ◽  
Luminal A ◽  
Case Presentation ◽  
Lymph Nodes Metastasis ◽  
First Case ◽  
Gene Test

Abstract Background: Breast cancer is rare in men and there is no report of male breast cancer (MBC) with ureteral metastasis. In this study, we report the first case of MBC with ureteral metastasis. Case presentation: A 60-year-old man was diagnosed with triple negative breast cancer (TNBC) with lymph nodes metastasis. After surgery, chemotherapy and radiotherapy he was diagnosed with ureter metastasis because of hematuria. This patient took a Precitype gene test (immune index and PAM50) after several lines of treatment and the result indicated that this was a Luminal A subtype case, which was quite different from his immunohistochemical staining. We adjusted his therapeutic regimen according to the genetic test but there was no obvious efficacy and he passed away five months later. Conclusions: MBC patients with urinary symptoms should be considered for the possibility of metastasis although urinary metastasis in breast cancer is rare. We still need more research and evidence of treatment recommendations for MBC.

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