Streptococcus constellatus: a rare causative agent of pyogenic liver abscess

A 26-year-old man who was previously well presented to the emergency in septic shock. He had a preceding history of fever, right upper abdominal pain and jaundice. On examination, there was tenderness over the right hypochondrium and epigastrium, without features of generalised peritonitis. His blood tests were suggestive of sepsis with deranged liver function tests. CT scan of the abdomen showed multiples abscesses in various segments of the liver and a thrombus in the inferior venacava, without any other intraabdominal focus of infection. The abscess was aspirated under sonographic guidance, and the cultures grew Streptococcus constellatus species of S. milleri group (SMG). He received crystalline penicillin, based on culture sensitivity and underwent drainage of the abscess. There was a clinical improvement and he was subsequently discharged in a stable condition. On 3 months follow-up, there was a complete resolution of the liver abscess and normalisation of the liver function tests.

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The Hematological Findings, Serum Protein Pattern and Liver Function Tests in Acute Amebic Dysentery and Amebic Liver Abscess *

American Journal of Tropical Medicine and Hygiene ◽

10.4269/ajtmh.1959.8.331 ◽

1959 ◽

Vol 8 (3) ◽

pp. 331-336 ◽

Cited By ~ 8

Author(s):

S. J. Powell

Keyword(s):

Liver Function ◽

Liver Abscess ◽

Serum Protein ◽

Protein Pattern ◽

Liver Function Tests ◽

Amebic Liver Abscess ◽

Amebic Dysentery ◽

Function Tests

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Liver function tests during amoebic liver abscess formation in indomethacin-treated hamsters

Journal of Experimental Zoology ◽

10.1002/jez.1050 ◽

2001 ◽

Vol 290 (3) ◽

pp. 201-206 ◽

Cited By ~ 2

Author(s):

Blanca Sánchez-Ramírez ◽

Sergio Mata-González ◽

Amelia Valdez ◽

Ernesto Ramos-Martínez ◽

Patricia Talamás-Rohana

Keyword(s):

Liver Function ◽

Liver Abscess ◽

Liver Function Tests ◽

Abscess Formation ◽

Amoebic Liver Abscess ◽

Function Tests

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Correlation between abscess size and liver function tests in cases of liver abscess

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20173158 ◽

2017 ◽

Vol 5 (8) ◽

pp. 3340

Author(s):

Vineet Jain ◽

Smita Manjavkar ◽

Divya Rajput ◽

Abhinav Jain ◽

. Jyotsana ◽

...

Keyword(s):

Liver Function ◽

Serum Albumin ◽

Liver Abscess ◽

Liver Enzymes ◽

Major Change ◽

Pyogenic Liver Abscess ◽

Liver Function Tests ◽

Amoebic Liver Abscess ◽

Male Preponderance ◽

Risk Patients

Background: Liver abscess has shown a major change in demographics, etiology, diagnosis, and treatment over the past 100 years. The modern diagnostics like ultrasound and computed tomography to locate and drain the abscess have reduced the mortality to 2-12%. However, due to the complications of liver abscess especially the amebic ones the morbidity is still high. This study aims to study the correlation of various LFT parameters with abscess volume for early detection of high risk patients and early treatment thus reducing morbidity.Methods: The study was conducted over a period of 6 months on 50 patients of liver abscess. History and physical examination was done. All patients were subjected to complete hemogram, liver function test, coagulation profile (PT/INR) and USG abdomen. The data was recorded and compiled in excel sheets and analyzed using correlation coefficient (R) method.Results: The mean age of the patients was 41.2 years with male preponderance. Amoebic liver abscess (88%) was predominant over pyogenic liver abscess (12%). Alcoholism (48%), smoking (42%) and diabetes mellitus (18%) are main predisposing factors in case of liver abscess. Hepatomegaly was found in 88% cases. Elevated ALP, low albumin, increased PT INR points to the diagnosis of liver abscess. Complications seen were pleural effusion (10%) and ascites (4%). On analysis, liver abscess size is significantly positively correlated with INR, ALP, liver enzymes, and negatively correlated with serum albumin level.Conclusions: Liver abscess size was found to be positively correlated with INR and alkaline phosphatase (ALP), liver enzymes (SGOT, SGPT) and negatively correlated with serum albumin levels. There was no correlation of abscess size and bilirubin levels. Hence, LFT can be used to estimate the liver abscess size and predict the severity and prognosis of patient.

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