Unusual presentation of granular cell tumour of buccal mucosa

2021 ◽  
Vol 14 (9) ◽  
pp. e242242
Author(s):  
Zhi Yon Charles Toh ◽  
Thomas Cooper ◽  
Maryam Jessri ◽  
Frank S-C Chang
Keyword(s):  
Buccal Mucosa ◽  
Correct Diagnosis ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Complete Surgical Excision ◽  
Uncommon Presentation ◽  
Long Term Follow Up

Granular cell tumour (GCT) is a rare soft tissue lesion which many consider to have malignant potential of yet unknown aetiopathogenesis. Oral GCT lesions may occur in an area of leucoplakia and are predominantly present on the tongue. This case study highlights an uncommon presentation of this condition located on the buccal mucosa and illustrates the need for meticulous evaluation of suspicious lesions. Due to the malignant risk associated with GCT lesions, it is important to make the correct diagnosis and ensure complete surgical excision for these cases. Ongoing long-term follow-up is also indicated to monitor for recurrence or malignancy.

scholarly journals Surgical Excision of Orbital Progressive Granular Cell Tumour

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Demetrio Germanò ◽  
Hossein Mostafa Elbadawy ◽  
Diego Ponzin ◽  
Daniele Ferro ◽  
Leonardo Priore
Keyword(s):  
Ct Scan ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Initial Examination ◽  
Orbital Mass ◽  
S 100 ◽  
Substantial Progress

Granular cell tumour (GCT) is mostly benign lesion first described by Abrikossoff and named after him. Most cases are reported in the head and neck area, where the tongue is the most common site. Here we review previous cases in the literature for GCT in the orbit and present a new case. A 49-year-old male presented with apparent exophthalmos. Examination of the patient revealed the presence of a mass in the bottom side of the orbit. A substantial progress was noted after two months from the initial examination using computed tomography (CT) scan. An orbital mass was extracted and histological analysis showed signs typical for GCT. Immunohistochemistry was positive for S-100; the biopsy showed no mitotic or necrotic areas. Proptosis was resolved after surgery and a six-year follow-up CT scan was performed. We conclude that rapid progress of the tumour does not necessarily suggest malignancy.

Granular cell tumour arising from the Kiesselbach's area of the nasal septum

2006 ◽  
Vol 121 (2) ◽  
pp. 170-173 ◽  
Author(s):  
T Sasaki ◽  
K Yamamoto ◽  
T Akashi
Keyword(s):  
Nasal Septum ◽  
Histopathological Examination ◽  
English Literature ◽  
Granular Cell ◽  
Surgical Excision ◽  
Japanese Woman ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Old Japanese ◽  
The Right

An extremely rare case of a granular cell tumour arising from the right Kiesselbach's area (Little's area) of the nasal septum is reported. A 69-year-old Japanese woman consulted our clinic and her chief complaints were of continuous serous discharge, stuffiness and occasional slight bleeding from the right nasal cavity. Fibrescopy showed a multilocular mass, which was provisionally considered a nasal polyp. Surgical excision was attempted. During surgery, the tumour shrank markedly following local application of adrenaline, suggestive of hypervascularity. The tumour was successfully excised by careful dissection after cauterisation of the mucosa surrounding the tumour. Histopathological examination revealed morphological features of granular cell tumour immunopositive for S-100 protein. This is the first report of granular cell tumour arising from the Kiesselbach's area in the English literature. The eccentric behaviour of the tumour and the management of a granular cell tumour arising from this area are discussed, together with a literature review.

scholarly journals Epiglottic granular cell tumour: a case report and literature review

2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Sarah Bouayyad ◽  
Jen Ong ◽  
Houda Bouayyad ◽  
Heerani Woodun
Keyword(s):  
Soft Tissues ◽  
Anterior Commissure ◽  
Incidental Finding ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
General Anaesthetic ◽  
Granular Cell Tumour ◽  
Rare Tumour ◽  
Rare Benign Tumour

Abstract Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic lesion during routine oesophagogastroscopy. Examination under general anaesthetic showed a whitish non-ulcerating exophytic lesion on the laryngeal surface of the epiglottis, sparing anterior commissure and vocal cords. Surgical excision was performed with an open supraglottic laryngectomy approach. Histopathology confirmed GCT, strongly positive for S-100 protein and weakly positive for CD68. Accurate histologic analysis is a key to identify this rare tumour among other differentials. Although benign, ongoing monitoring is advised due to risk of recurrence.

scholarly journals CONGENITAL GRANULAR CELL TUMOUR : A RARE CASE REPOR

2020 ◽  
pp. 1-2
Author(s):  
Sabari Devi ◽  
Waziha Ahmed
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Recurrence Rate ◽  
Rare Case ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Feeding Problems

Congenital granular cell tumour/ epulis (CGCE) is a rare benign lesion of the newborn. It was first described in 1871 by Neumann. It usually arises from the alveolar mucosa of neonates and may cause respiratory and feeding problems. The exact histogenesis is unclear. The proposed source of origin includes undifferentiated mesenchymal cells, odontogenic epithelial, pericytes, fibroblasts, smooth muscle cells. Treatment involves surgical excision and and its curative with rare recurrence rate.

scholarly journals Massive angiomyofibroblastoma of the glans penis

2019 ◽  
Vol 12 (6) ◽  
pp. e229486 ◽  
Author(s):  
Sherif Monib ◽  
Mohamed Ibrahim
Keyword(s):  
Surgical Excision ◽  
Distant Recurrence ◽  
Glans Penis ◽  
Complete Surgical Excision ◽  
Long Term Follow Up ◽  
Rare Benign Tumour ◽  
Guide Lines ◽  
Male Genital

Male genital tract angiomyofibroblastoma (AMF) is a rare benign tumour, with a total of 34 cases reported in literature. We are presenting a case of AMF of the glans penis in a 68-year-old man who presented with a progressively increasing in size large lesion located on the tip of his penis. Following routine investigations, the lesion was surgically excised with no adjuvant treatment, the patient was followed-up for 5 years with no evidence of local, nodal or distant recurrence. As AMF of the glans penis is extremely rare, there is not enough literature to support management guide lines, but it appears that AMF responds very well to complete surgical excision; occasional cases of recurrence have been previously reported, so a long-term follow-up is advised.

scholarly journals Granular cell tumour of clitoris: a case report

2019 ◽  
Vol 8 (5) ◽  
pp. 2146
Author(s):  
Alka Goel ◽  
Anupriya Narain ◽  
Khushboo Singh ◽  
Minakshi Bhardwaj
Keyword(s):  
Subcutaneous Tissue ◽  
Neck Region ◽  
Granular Cell ◽  
Surgical Excision ◽  
Muscle Layer ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Rare Site ◽  
Granular Cell Tumours ◽  
Slow Growing

Granular cell tumour (GCT) is tumours showing neuroectodermal differentiation. It occurs mostly in the dermis and subcutaneous tissue and occurrence in the muscle layer is rare. The most common site is the head and neck region. It has been known to occur in the vulva, with clitoris being a very rare site. Granular cell tumours are slow growing tumours, which are mostly asymptomatic. We report a case of lump in the clitoris in a 42-year-old woman which was managed with surgical excision. Histopathology confirmed the diagnosis of granular cell tumour. Very few cases of granular cell tumour of clitoris have been reported in literature till date. Although mostly benign, the differential diagnosis of granular cell tumour should be borne in mind by the clinicians in cases of clitoral lump.

GRANULAR CELL TUMOUR IN A MALE BREAST

1973 ◽  
Vol 2 (22) ◽  
pp. 1010-1011 ◽  
Author(s):  
Stewart Hart ◽  
Lorna Sisely
Keyword(s):  
Granular Cell ◽  
Male Breast ◽  
Cell Tumour ◽  
Granular Cell Tumour

Granular cell tumour in a patient with Crohn’s disease treated with infliximab

2012 ◽  
Vol 24 (7) ◽  
pp. 857-859 ◽  
Author(s):  
Konstantinos Papamichael ◽  
Emmanuel Archavlis ◽  
Constantina Lariou ◽  
Alexia Tsigka ◽  
Gerassimos J. Mantzaris
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Granular Cell ◽  
Cell Tumour ◽  
Granular Cell Tumour
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