scholarly journals Epiglottic granular cell tumour: a case report and literature review

2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Sarah Bouayyad ◽  
Jen Ong ◽  
Houda Bouayyad ◽  
Heerani Woodun
Keyword(s):  
Soft Tissues ◽  
Anterior Commissure ◽  
Incidental Finding ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
General Anaesthetic ◽  
Granular Cell Tumour ◽  
Rare Tumour ◽  
Rare Benign Tumour

Abstract Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic lesion during routine oesophagogastroscopy. Examination under general anaesthetic showed a whitish non-ulcerating exophytic lesion on the laryngeal surface of the epiglottis, sparing anterior commissure and vocal cords. Surgical excision was performed with an open supraglottic laryngectomy approach. Histopathology confirmed GCT, strongly positive for S-100 protein and weakly positive for CD68. Accurate histologic analysis is a key to identify this rare tumour among other differentials. Although benign, ongoing monitoring is advised due to risk of recurrence.

Unusual presentation of granular cell tumour of buccal mucosa

2021 ◽  
Vol 14 (9) ◽  
pp. e242242
Author(s):  
Zhi Yon Charles Toh ◽  
Thomas Cooper ◽  
Maryam Jessri ◽  
Frank S-C Chang
Keyword(s):  
Buccal Mucosa ◽  
Correct Diagnosis ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Complete Surgical Excision ◽  
Uncommon Presentation ◽  
Long Term Follow Up

Granular cell tumour (GCT) is a rare soft tissue lesion which many consider to have malignant potential of yet unknown aetiopathogenesis. Oral GCT lesions may occur in an area of leucoplakia and are predominantly present on the tongue. This case study highlights an uncommon presentation of this condition located on the buccal mucosa and illustrates the need for meticulous evaluation of suspicious lesions. Due to the malignant risk associated with GCT lesions, it is important to make the correct diagnosis and ensure complete surgical excision for these cases. Ongoing long-term follow-up is also indicated to monitor for recurrence or malignancy.

scholarly journals Surgical Excision of Orbital Progressive Granular Cell Tumour

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Demetrio Germanò ◽  
Hossein Mostafa Elbadawy ◽  
Diego Ponzin ◽  
Daniele Ferro ◽  
Leonardo Priore
Keyword(s):  
Ct Scan ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Initial Examination ◽  
Orbital Mass ◽  
S 100 ◽  
Substantial Progress

Granular cell tumour (GCT) is mostly benign lesion first described by Abrikossoff and named after him. Most cases are reported in the head and neck area, where the tongue is the most common site. Here we review previous cases in the literature for GCT in the orbit and present a new case. A 49-year-old male presented with apparent exophthalmos. Examination of the patient revealed the presence of a mass in the bottom side of the orbit. A substantial progress was noted after two months from the initial examination using computed tomography (CT) scan. An orbital mass was extracted and histological analysis showed signs typical for GCT. Immunohistochemistry was positive for S-100; the biopsy showed no mitotic or necrotic areas. Proptosis was resolved after surgery and a six-year follow-up CT scan was performed. We conclude that rapid progress of the tumour does not necessarily suggest malignancy.

Granular cell tumour arising from the Kiesselbach's area of the nasal septum

2006 ◽  
Vol 121 (2) ◽  
pp. 170-173 ◽  
Author(s):  
T Sasaki ◽  
K Yamamoto ◽  
T Akashi
Keyword(s):  
Nasal Septum ◽  
Histopathological Examination ◽  
English Literature ◽  
Granular Cell ◽  
Surgical Excision ◽  
Japanese Woman ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Old Japanese ◽  
The Right

An extremely rare case of a granular cell tumour arising from the right Kiesselbach's area (Little's area) of the nasal septum is reported. A 69-year-old Japanese woman consulted our clinic and her chief complaints were of continuous serous discharge, stuffiness and occasional slight bleeding from the right nasal cavity. Fibrescopy showed a multilocular mass, which was provisionally considered a nasal polyp. Surgical excision was attempted. During surgery, the tumour shrank markedly following local application of adrenaline, suggestive of hypervascularity. The tumour was successfully excised by careful dissection after cauterisation of the mucosa surrounding the tumour. Histopathological examination revealed morphological features of granular cell tumour immunopositive for S-100 protein. This is the first report of granular cell tumour arising from the Kiesselbach's area in the English literature. The eccentric behaviour of the tumour and the management of a granular cell tumour arising from this area are discussed, together with a literature review.

scholarly journals Presentation of a Case Report and Literature Review on Granular Cell Tumour of the Breast

2020 ◽  
pp. 24-29
Author(s):  
Raymond Akpobome Vhriterhire ◽  
Joseph Aondowase Ngbea ◽  
David Gyenger ◽  
B. A. Eke
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Granular Cell ◽  
Excisional Biopsy ◽  
Cell Tumour ◽  
Histological Evaluation ◽  
Granular Cell Tumour ◽  
Diagnostic Dilemma ◽  
Rare Tumour ◽  
Recent Onset

A 21 years old woman presented with a breast swelling of 4 years duration and with an associated pain of a more recent onset. On clinical examination, the mass was found to be firm, mobile and without attachment to the skin or surrounding structures. An excisional biopsy was performed based on a provisional clinical diagnosis of fibroadenoma. However, histological evaluation showed the tumour to be a granular cell tumour. The clinical features of this rare tumour may mimic a variety of conditions and cause a diagnostic dilemma.

scholarly journals Congenital granular cell tumour - a case report

2021 ◽  
Vol 9 (2) ◽  
pp. 627
Author(s):  
Atheetha R. ◽  
Sankar Sundaram
Keyword(s):  
Case Report ◽  
Anterior Segment ◽  
Granular Cell ◽  
Benign Tumour ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Male Baby ◽  
Upper Jaw ◽  
Rare Benign Tumour

Congenital granular cell tumour (epulis) is a rare benign tumour occurring in gingiva of neonates, of unknown histogenesis, predominantly occurring in girls. It can cause feeding and respiratory difficulty. We describe a case of a newborn male baby born with swelling in the gingiva of anterior segment of upper jaw. The lesion was excised, with baby doing well at follow up.  

scholarly journals Congenital granular cell epulis: report of a case and review of the literature

2019 ◽  
Vol 9 (1) ◽  
pp. 46-50
Author(s):  
E.B. Edetanlen ◽  
C.B. Ogboh
Keyword(s):  
Soft Tissues ◽  
Clinical Presentation ◽  
Benign Lesion ◽  
Maxillofacial Surgery ◽  
Granular Cell ◽  
Surgical Excision ◽  
Oral And Maxillofacial Surgery ◽  
Granular Cell Tumour ◽  
Review Of The Literature ◽  
New Born

Congenital granular cell tumour of the new born is a rare benign lesion of soft tissues which normally affects the maxillary alveolar ridge in neonates. Though benign, it can cause respiratory embarrassment and prevent feeding causing physical distress to the infant and psychological distress to the parents or guardian. Very few cases are reported in the literature. We aimed to highlight the clinical presentation, management and a brief review of the literature of the lesion.A case of a 3-day old baby who presented to the Oral and Maxillofacial Surgery Clinic University of Benin Teaching Hospital (UBTH) was used to illustrate the clinical presentation and management of congenital epulis.Congenital epulis of the new-born is a rare occurrence, though it can grow to a frightening size, it still remains a benign lesion with li le or no recurrence following surgical excision. The role of counselling to the parents cannot be over-emphasized.Keywords: Congenital, epulis, granular, newborn

scholarly journals CONGENITAL GRANULAR CELL TUMOUR : A RARE CASE REPOR

2020 ◽  
pp. 1-2
Author(s):  
Sabari Devi ◽  
Waziha Ahmed
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Recurrence Rate ◽  
Rare Case ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Feeding Problems

Congenital granular cell tumour/ epulis (CGCE) is a rare benign lesion of the newborn. It was first described in 1871 by Neumann. It usually arises from the alveolar mucosa of neonates and may cause respiratory and feeding problems. The exact histogenesis is unclear. The proposed source of origin includes undifferentiated mesenchymal cells, odontogenic epithelial, pericytes, fibroblasts, smooth muscle cells. Treatment involves surgical excision and and its curative with rare recurrence rate.

scholarly journals Granular cell tumour of clitoris: a case report

2019 ◽  
Vol 8 (5) ◽  
pp. 2146
Author(s):  
Alka Goel ◽  
Anupriya Narain ◽  
Khushboo Singh ◽  
Minakshi Bhardwaj
Keyword(s):  
Subcutaneous Tissue ◽  
Neck Region ◽  
Granular Cell ◽  
Surgical Excision ◽  
Muscle Layer ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Rare Site ◽  
Granular Cell Tumours ◽  
Slow Growing

Granular cell tumour (GCT) is tumours showing neuroectodermal differentiation. It occurs mostly in the dermis and subcutaneous tissue and occurrence in the muscle layer is rare. The most common site is the head and neck region. It has been known to occur in the vulva, with clitoris being a very rare site. Granular cell tumours are slow growing tumours, which are mostly asymptomatic. We report a case of lump in the clitoris in a 42-year-old woman which was managed with surgical excision. Histopathology confirmed the diagnosis of granular cell tumour. Very few cases of granular cell tumour of clitoris have been reported in literature till date. Although mostly benign, the differential diagnosis of granular cell tumour should be borne in mind by the clinicians in cases of clitoral lump.

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