Successful non-surgical treatment of pseudomonas choroidal abscess in cystic fibrosis with previous double lung transplantation

Pseudomonas aeruginosa choroidal abscess is a rare condition which tends to affect patients with cystic fibrosis (CF) who have undergone double lung transplantation. Various surgical treatment strategies have been described but almost universally have had a dismal prognosis. We present a case of pseudomonas choroidal abscess in a CF patient with previous double lung transplantation who was managed with medical treatment, with intravitreal and systemic antibiotics, without surgical intervention, which led to successful resolution of the choroidal abscess, preservation of the eye and retention of vision.

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Modern Non-Surgical Treatment Strategies for Peyronie’s Disease

Textbook of Male Genitourethral Reconstruction ◽

10.1007/978-3-030-21447-0_38 ◽

2019 ◽

pp. 467-481

Author(s):

Matthew J. Ziegelmann ◽

Landon W. Trost ◽

Laurence A. Levine

Keyword(s):

Surgical Treatment ◽

Treatment Strategies ◽

Peyronie’S Disease ◽

Peyronie's Disease ◽

Non Surgical Treatment

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Concurrent inhibition of TGF-β and mitogen driven signaling cascades in Dupuytren’s disease – Non-surgical treatment strategies from a signaling point of view

Medical Hypotheses ◽

10.1016/j.mehy.2011.11.023 ◽

2012 ◽

Vol 78 (3) ◽

pp. 385-388 ◽

Cited By ~ 3

Author(s):

C. Krause ◽

P. Kloen

Keyword(s):

Surgical Treatment ◽

Treatment Strategies ◽

Point Of View ◽

Signaling Cascades ◽

Dupuytren’S Disease ◽

Dupuytren's Disease ◽

Non Surgical Treatment

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Efficacy of alternative or adjunctive measures to conventional non-surgical and surgical treatment of peri-implant mucositis and peri-implantitis: a systematic review and meta-analysis

International Journal of Implant Dentistry ◽

10.1186/s40729-021-00388-x ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Ausra Ramanauskaite ◽

Tobias Fretwurst ◽

Frank Schwarz

Keyword(s):

Surgical Treatment ◽

Soft Tissue ◽

Bone Defect ◽

Weighted Mean Difference ◽

Meta Analysis ◽

Mucosal Inflammation ◽

Biofilm Removal ◽

Alternative Measures ◽

Systemic Antibiotics ◽

Non Surgical Treatment

Abstract Purpose To evaluate the efficacy of alternative or adjunctive measures to conventional non-surgical or surgical treatment of peri-implant mucositis and peri-implantitis. Material and methods Prospective randomized and nonrandomized controlled studies comparing alternative or adjunctive measures, and reporting on changes in bleeding scores (i.e., bleed0ing index (BI) or bleeding on probing (BOP)), probing depth (PD) values or suppuration (SUPP) were searched. Results Peri-implant mucositis: adjunctive use of local antiseptics lead to greater PD reduction (weighted mean difference (WMD) = − 0.23 mm; p = 0.03, respectively), whereas changes in BOP were comparable (WMD = − 5.30%; p = 0.29). Non-surgical treatment of peri-implantitis: alternative measures for biofilm removal and systemic antibiotics yielded higher BOP reduction (WMD = − 28.09%; p = 0.01 and WMD = − 17.35%; p = 0.01, respectively). Surgical non-reconstructive peri-implantitis treatment: WMD in PD amounted to − 1.11 mm favoring adjunctive implantoplasty (p = 0.02). Adjunctive reconstructive measures lead to significantly higher radiographic bone defect fill/reduction (WMD = 56.46%; p = 0.01 and WMD = − 1.47 mm; p = 0.01), PD (− 0.51 mm; p = 0.01) and lower soft-tissue recession (WMD = − 0.63 mm; p = 0.01), while changes in BOP were not significant (WMD = − 11.11%; p = 0.11). Conclusions Alternative and adjunctive measures provided no beneficial effect in resolving peri-implant mucositis, while alternative measures were superior in reducing BOP values following non-surgical treatment of peri-implantitis. Adjunctive reconstructive measures were beneficial regarding radiographic bone-defect fill/reduction, PD reduction and lower soft-tissue recession, although they did not improve the resolution of mucosal inflammation.

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Newborn Nasal Obstruction due to Congenital Nasal Pyriform Aperture Stenosis

Allergy & Rhinology ◽

10.2500/ar.2016.7.0146 ◽

2016 ◽

Vol 7 (1) ◽

pp. ar.2016.7.0146 ◽

Cited By ~ 4

Author(s):

Thiago L. I. Serrano ◽

Leopoldo Pfeilsticker ◽

Vanessa Silva ◽

Igor Hazboun ◽

Jorge Paschoal ◽

...

Keyword(s):

Surgical Treatment ◽

Respiratory Distress ◽

Nasal Cavity ◽

Nasal Obstruction ◽

Treatment Strategies ◽

Rare Condition ◽

Surgical Correction ◽

Severe Respiratory Distress ◽

First Case ◽

Pyriform Aperture

Introduction Nasal obstruction is an important condition that can lead to severe respiratory distress in newborns. There are several differential diagnoses, and one of them is congenital nasal pyriform aperture stenosis (CNPAS). CNPAS is a rare case of respiratory distress caused by excessive growth of the nasal process of the maxilla and leads to narrowing of the anterior third of the nasal cavity. Diagnosis, associated anomalies, and treatment strategies are reviewed by the following presentation of two cases. Case Presentation We report two cases of infants diagnosed with CNPAS. The patients in the first case had no concomitant comorbidities, and the outcome was successful after surgical correction of stenosis. The patient in the second case had an associated holoprosencephaly, and although surgical correction and nasal cavity patency, the patient remains dependent on tracheostomy due to dysphagia and neurologic impairment. Discussion Airway obstruction affects 1 in 5000 children, and CNPAS is a diagnosis frequently forgotten and even unknown to neonatal and pediatric intensivists. Newborns are obligate nasal breathers, and, nasal obstruction, therefore, can lead to severe respiratory distress. CNPAS is not only rare but, many times, is not easily recognized. It is important to bear in mind the diagnostic criteria when evaluating infants with nasal obstruction. Conservative treatment should be prioritized, but surgical treatment is required in severe cases with failure to thrive and persistent respiratory distress. Respiratory distress and dysphagia may persist to some degree despite correction of the stenotic pyriform aperture due to associated narrowing of the entire nasal cavity and association with other anomalies. Final Comments CNPAS is a rare condition and may be lethal in newborns. Differential diagnosis of nasal obstruction must be remembered to recognize this anomaly, and the otolaryngologist must be familiarized with this condition and its diagnosis. Precise surgical treatment in severe cases have high rates of success in children without other comorbidities.

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Idiopathic chylothorax in geriatrics: the oldest case report so far

Turkish Journal of Biochemistry ◽

10.1515/tjb-2018-0193 ◽

2018 ◽

Vol 43 (5) ◽

pp. 564-567

Author(s):

Belkız Öngen İpek ◽

Elçin Akduman Alaşehir ◽

Mustafa Erinç Sitar ◽

Ender Levent ◽

Alpay Orki

Keyword(s):

Case Report ◽

Surgical Treatment ◽

Pleural Effusion ◽

Laboratory Tests ◽

Rare Condition ◽

Pleural Space ◽

Disease Etiology ◽

Trauma History ◽

Distress Symptoms ◽

Non Surgical Treatment

Abstract Chylothorax is a rare condition characterized by accumulation of chylous fluid in the pleural space resulting in impaired ductus thoracic integrity. It can be an outcome of a traumatic process, although there are a few non-traumatic and/or idiopathic cases in current literature. In this article, we present the oldest case report so for, who is an 87-year-old woman complaining of acute respiratory distress symptoms with pleural effusion having no trauma history. The patient was analyzed for the disease etiology strenuously. Thoracentesis was performed together with imaging modalities and detailed systemic laboratory tests. Non-surgical treatment was successful as the outcome.

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Spontaneous Subcapsular Renal Hematoma as a Complication of Acute Pyelonephritis: A Case Report

Serbian Journal of Experimental and Clinical Research ◽

10.1515/sjecr-2016-0091 ◽

2017 ◽

Vol 18 (4) ◽

pp. 357-359

Author(s):

Ivan Jankovic ◽

Tomislav Nikolic ◽

Slobodanka Mitrovic ◽

Radisa Vojinovic

Keyword(s):

Surgical Treatment ◽

Antibiotic Therapy ◽

Acute Pyelonephritis ◽

Percutaneous Drainage ◽

Imaging Techniques ◽

Left Kidney ◽

Rare Condition ◽

Subcapsular Hematoma ◽

First Choice ◽

Non Surgical Treatment

AbstractSpontaneous subcapsular renal hematoma (SSRH) emerged as a complication of acute pyelonephritis (APN) is an extremely rare condition. We showed a patient aged 63 years hospitalized due to languor, febrility, abdominal pain accompanied by nausea and vomiting. Ultrasound (US) examination of the abdomen and multidetector computed tomography (MDCT) showed the presence of subcapsular hematoma of the left kidney with calculus in the initial part of the left ureter. Laboratory tests registered a positive inflammation syndrome, anemia and an increase in nitrogen compounds. Based on laboratory results, clinical presentation and imaging techniques it has been found that it is APN with spontaneous subcapsular hematoma. After application of non-surgical treatment which included antibiotic therapy with percutaneous drainage of hematoma, a good clinical response with regression of subjective symptoms and hematoma was obtained. On repeated US and MDCT after 18 months no pathological changes in the kidneys were registered. Spontaneous subcapsular hematoma extremely rare occurs as a result of APN associated with calculosis. The use of non-surgical treatment, which includes appropriate antibiotic therapy with percutaneous drainage of hematoma would represent a method of first choice.

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