Cerebellar progressive multifocal leukoencephalopathy associated with pulmonary sarcoidosis

2021 ◽  
Vol 14 (9) ◽  
pp. e245271
Author(s):  
Lajjaben Patel ◽  
Arunmozhimaran Elavarasi ◽  
Ajay Garg ◽  
Aruna Nambirajan

Progressive multifocal leukoencephalopathy can complicate the course of a patient with sarcoidosis. Here we present a rare case of a 35-year-old patient with pulmonary sarcoidosis whose course was complicated by progressive multifocal leukoencephalopathy involving the cerebellum. Neuroimaging and cerebrospinal fluid PCR played a crucial role in the diagnosis.

Author(s):  
Meenakshi Gothwal ◽  
Charu Sharma ◽  
Garima Yadav ◽  
Pratibha Singh ◽  
Sunil Raikar

Conjoined twin is a rare complication seen in 1% of monochorionic twins and associated with severe morbidity and mortality. It occurs due to a division event at the primitive streak stage of the human embryonic development at about 13-14 days after fertilisation, in monochorionic monoamniotic gestations.  Early prenatal diagnosis of conjoined twin plays a very crucial role in the management and allows appropriate and timely counselling of couple regarding the different modes of management like early termination of pregnancy or continuation of pregnancy with post-natal surgery. Late diagnoses present with difficult options for parents and obstetrician too. Ultrasound plays a very crucial role in diagnosis of conjoined twin. We are reporting a case of 27 years old primigravida referred to our institute at 13 weeks of gestation with ultra-sonographic diagnosis of dicephalus parapagus conjoined twin and further confirmed after termination of pregnancy.


Cureus ◽  
2021 ◽  
Author(s):  
Pinak Shah ◽  
Kartika Shetty ◽  
Maycky Tang ◽  
Elnaz Saberi ◽  
Nazanin Sheikhan

2007 ◽  
Vol 6 (3) ◽  
pp. 276-279 ◽  
Author(s):  
Erwin M. J. Cornips ◽  
Julie Staals ◽  
Angela Stavast ◽  
Kim Rijkers ◽  
Robert J. Van Oostenbrugge

✓ The authors present a rare case of fatal cerebral and cerebellar hemorrhagic infarction following an uneventful thoracoscopic microdiscectomy. They hypothesize that this complication was associated with cortical venous thrombosis secondary to intracranial hypotension, which was caused by an unnoticed leak of cerebrospinal fluid (CSF) into the thoracic cavity. Cortical venous thrombosis and intrathoracic CSF were confirmed at autopsy. The former disorder is the most severe manifestation of the pathophysiological mechanism occurring to a lesser degree in patients affected by mild intracranial hypotension, and occurs more frequently in these patients. Intracranial hypotension (of an orthostatic nature or not) must be considered in the differential diagnosis of every patient who complains of headaches after thoracoscopic or open transthoracic microdiscectomy.


2018 ◽  
Vol 69 (1) ◽  
pp. 53-55
Author(s):  
Karthikeyan Ramasamy ◽  
Hemanth Vamanshankar ◽  
Sunil Kumar Saxena ◽  
Vignesh Karunakaran ◽  
Arun Alexander

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Xiaoming Yu ◽  
Keji Miao ◽  
Changsheng Zhou ◽  
Yuelin Cai ◽  
Xiaoying Huang ◽  
...  

2011 ◽  
Vol 17 (2) ◽  
pp. 248-251 ◽  
Author(s):  
K-W. Yoon ◽  
M-K. Cho ◽  
Y.J. Kim ◽  
C.S. Cho ◽  
S-K. Lee

We describe the case of a 26-year-old man with orthostatic headache. Cerebral angiography revealed thrombosis in the sagittal sinus. Spine MRI showed cerebrospinal fluid collection at the C1–2 level. We performed blood patch and the symptoms disappeared. We report a rare case of intracranial hypotension caused by CSF leak and describe our hypothesis that SIH can change the velocity of cerebral blood flow and cause thrombosis.


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