scholarly journals Effects of photobiomodulation therapy combined to static magnetic field in strength training and detraining in humans: protocol for a randomised placebo-controlled trial

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e030194
Author(s):  
Paulo Roberto Vicente de Paiva ◽  
Heliodora Leão Casalechi ◽  
Shaiane Silva Tomazoni ◽  
Caroline dos Santos Monteiro Machado ◽  
Adriane Aver Vanin ◽  
...  

IntroductionIn recent years, it has been demonstrated that photobiomodulation therapy (PBMT) using low-level laser therapy and/or light-emitting diode therapy combined to static magnetic field (sMF) has ergogenic effects, improving muscular performance and accelerating postexercise recovery. However, many aspects related to these effects and its clinical applicability remain unknown. Therefore, the aim of this project is to evaluate the ergogenic effects of PBMT/sMF in detraining after a strength-training protocol.Methods and analysisThe study will be a randomised, triple-blind, placebo-controlled clinical trial. Healthy male volunteers will be randomly distributed into four experimental groups: PBMT/sMF before training sessions + PBMT/sMF during detraining, PBMT/sMF before training sessions + placebo during detraining, placebo before training sessions + PBMT/sMF during detraining and placebo before training sessions + placebo during detraining. Strength-training sessions will be carried out over 12 weeks, and the detraining period will occur during the 4 weeks after. The muscular strength and the structural properties of quadriceps will be analysed.Ethics and disseminationThis study was approved by the Research Ethics Committee of Nove de Julho University. The results from this study will be disseminated through scientific publications in international peer-reviewed journals and presented at national and international scientific meetings.Trial registration numberNCT03858179.

Author(s):  
Caroline dos Santos Monteiro Machado ◽  
Heliodora Leão Casalechi ◽  
Adriane Aver Vanin ◽  
Jônatas Bezerra de Azevedo ◽  
Paulo de Tarso Camillo de Carvalho ◽  
...  

Abstract Background The direct application of photobiomodulation therapy (PBMT) using low-level laser therapy (LLLT) and light emitting diodes (LEDs) combined with a static magnetic field (sMF) (PBMT-sMF) to target tissues is shown to improve muscle performance and recovery. Studies have reported possible PBMT effects when a local distant to the target tissue is irradiated. Notably, the extent of these effects on musculoskeletal performance and the optimal site of irradiation remain unclear, although this information is clinically important since these aspects could directly affect the magnitude of the effect. Therefore, we investigated the effects of local and non-local PBMT-sMF irradiations on musculoskeletal performance and post-exercise recovery before an eccentric exercise protocol. Methods This randomized, triple-blind (participants, therapists and assessors), placebo-controlled trial included 30 healthy male volunteers randomly assigned to the placebo, local, and non-local groups. Active or placebo PBMT-sMF was applied to 6 sites of the quadriceps muscle of both legs. An eccentric exercise protocol was used to induce fatigue. The primary outcome was peak torque assessed by maximal voluntary contraction (MVC). The secondary outcomes were delayed onset muscle soreness (DOMS) measured by visual analogue scale (VAS), muscle injury assessed by serum creatine kinase activity (CK), and blood lactate levels. Evaluations were performed before the eccentric exercise protocol (baseline), as well as immediately after and 1, 24, 48, and 72 h upon protocol completion. Results Ten volunteers were randomized per group and analysed for all outcomes. Compared to the placebo and non-local groups, irradiation with PBMT-SMF led to statistically significant improvement (p < 0.05) with regard to all variables in the local group. The outcomes observed in the non-local group were similar to those in the placebo group with regard to all variables. The volunteers did not report any adverse effects. Conclusion Our results support the current evidence that local irradiation of all exercised muscles promotes ergogenic effects. PBMT-sMF improved performance and reduced muscle fatigue only when applied locally to muscles involved in physical activity. Trial registration NCT03695458. Registered October 04th 2018.


2021 ◽  
Vol Volume 14 ◽  
pp. 3569-3585
Author(s):  
Thiago De Marchi ◽  
Fabiano Frâncio ◽  
João Vitor Ferlito ◽  
Renata Weigert ◽  
Cristiane de Oliveira ◽  
...  

2020 ◽  
Author(s):  
Caroline dos Santos Monteiro Machado ◽  
Heliodora Leão Casalechi ◽  
Adriane Aver Vanin ◽  
Jônatas Bezerra de Azevedo ◽  
Paulo de Tarso Camillo de Carvalho ◽  
...  

Abstract Background The direct application of photobiomodulation therapy (PBMT) combined with a static magnetic field (sMF) (PBMT-sMF) to target tissues is shown to improve muscle performance and recovery. Studies have reported possible PBMT induced systemic effects. Notably, the extent of these effects on musculoskeletal performance and the optimal site of application remain unclear, although this information is clinically important because these factors directly affect the magnitude of the effect. We investigated the effects of PBMT-sMF on musculoskeletal performance and post-exercise recovery of muscles in exercised and non-exercised legs before the implementation of an exercise protocol.Methods This randomized, triple-blind placebo-controlled study included 30 healthy men randomly assigned to the placebo, exercised-leg, and non-exercised leg groups. Active or placebo PBMT-sMF was applied to 6 sites of the quadriceps muscle of both legs. An eccentric exercise protocol was used to induce fatigue. The following parameters were analyzed to evaluate exercise performance: peak torque assessed by maximal voluntary contraction (MVC), delayed muscle pain assessed by the visual analogue scale (VAS), muscle injury assessed by serum creatine kinase (CK), and fatigue assessed by serum lactate levels. Evaluations were performed before implementation of the eccentric (baseline) exercise protocol, as well as immediately after and 1, 24, 48, and 72 hours upon protocol completion. The Bonferroni post-hoc ANOVA test was used considering the level of statistical significance p <0.05.Results Compared to the placebo and systemic groups, irradiation with PBMT-SMF led to statistically significant improvement (p <0.05) with regard to all variables in the exercised-leg group. Results of irradiation in the non-exercised leg group were similar to those in the placebo group with regard to all variables.Conclusion Our results support the current evidence that irradiation of all exercised muscles produces ergogenic effects. PBMT-sMF improved performance and reduced muscle fatigue only when applied locally to muscles involved in physical activity.


Life ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1124
Author(s):  
Shaiane Silva Tomazoni ◽  
Douglas Scott Johnson ◽  
Ernesto Cesar Pinto Leal-Junior

Introduction: Photobiomodulation therapy, alone (PBMT) or combined with a static magnetic field (PBMT-sMF), has been demonstrated to be effective in the regeneration of tissues, modulation of inflammatory processes, and improvement in functional capacity. However, the effects of PBMT-sMF on the pulmonary system and COVID-19 patients remain scarce. Therefore, in this case report, we demonstrated the use of PBMT-sMF for peripheral oxygen saturation, pulmonary function, massive lung damage, and fibrosis as a pulmonary complication after COVID-19. Case report: A 53-year-old Mexican man who presented with decreased peripheral oxygen saturation, massive lung damage, and fibrosis after COVID-19 received PBMT-sMF treatment once a day for 45 days. The treatment was irradiated at six sites in the lower thorax and upper abdominal cavity and two sites in the neck area. We observed that the patient was able to leave the oxygen support during the treatment, and increase his peripheral oxygen saturation. In addition, the patient showed improvements in pulmonary severity scores and radiological findings. Finally, the patient presented with normal respiratory mechanics parameters in the medium-term, indicating total pulmonary recovery. Conclusions: The use of PBMT-sMF may potentially lead to safe treatment of and recovery from pulmonary complications after COVID-19, with regard to the structural and functional aspects.


2021 ◽  
Vol 4 (1) ◽  
pp. 19
Author(s):  
Martin Bjørn Stausholm ◽  
Ingvill Fjell Naterstad ◽  
Christian Couppé ◽  
Kjartan Vibe Fersum ◽  
Ernesto Cesar Pinto Leal-Junior ◽  
...  

Physical activity and low-level laser therapy (LLLT) can reduce knee osteoarthritis (KOA) inflammation. We are conducting a randomized placebo-controlled trial to investigate the long-term effectiveness of LLLT combined with strength training (ST) in persons with KOA, since it, to our knowledge, has not been investigated before. Fifty participants were enrolled. LLLT and ST was performed 3 times per week over 3 and 8 weeks, respectively. In the LLLT group, 3 Joules of 904 nm wavelength laser was applied to 15 spots per knee (45 Joules/knee/session). The primary outcomes are pain during movement, at night and at rest (Visual Analogue Scale) and global pain (Knee injury and Osteoarthritis Outcome Score, KOOS) pain subscale. The secondary outcomes are KOOS disability and quality-of-life, analgesic usage, global health change, knee active range of motion, 30 second chair stand, maximum painless isometric knee extension strength, knee pain pressure threshold and real-time ultrasonography-assessed suprapatellar effusion, meniscal neovascularization and femur cartilage thickness. All the outcomes are assessed 0, 3, 8, 26 and 52 weeks post-randomization, except for global health change, which is only evaluated at completed ST. This study features the blinding of participants, assessors and therapists, and will improve our understanding of what occurs with the local pathophysiology, tissue morphology and clinical status of persons with KOA up to a year after the initiation of ST and a higher 904 nm LLLT dose than in any published trial on this topic.


2019 ◽  
Vol 35 (3) ◽  
pp. 759-764
Author(s):  
Carolina Gassen Fritsch ◽  
Laura Ayang Folgiarini ◽  
Natália Sgarioni Gomes ◽  
Marco Aurélio Vaz ◽  
Bruno Manfredini Baroni

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