scholarly journals Attitudes of patients and surgeons towards sham surgery trials: a protocol for a scoping review of attributes to inform a discrete choice experiment

BMJ Open ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. e035870
Author(s):  
Laura Wall ◽  
Madeleine Hinwood ◽  
Danielle Lang ◽  
Angela Smith ◽  
Samantha Bunzli ◽  
...  
Keyword(s):  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Scoping Review ◽  
Choice Experiment ◽  
Included Study ◽  
Willingness To Participate ◽  
Sham Surgery ◽  
Scoping Reviews ◽  
Randomised Controlled ◽  
Surgery Trial

IntroductionIn order to properly evaluate the efficacy of orthopaedic procedures, rigorous, randomised controlled sham surgery trial designs are necessary. However, randomised controlled trials (RCTs) for surgery involving a placebo are ethically debated and difficult to conduct with many failing to reach their desired sample size and power. A review of the literature on barriers and enablers to recruitment, and patient and surgeon attitudes and preferences towards sham surgery trials, will help to determine the characteristics necessary for successful recruitment.Methods and analysisThis review will scope the diverse literature surrounding sham surgery trials with the aim of informing a discrete choice experiment to empirically test patient and surgeon preferences for different sham surgery trial designs. The scoping review will be conducted in accordance with the methodological framework described in Arksey and O’Malley (2005) and reported using the Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocols extension for Scoping Reviews. The review will be informed by a systematic search of Medline, Embase, PsycInfo, CINAHL and EconLit databases (from database inception to 21 June 2019), a Google Scholar search, and hand searching of reference lists of relevant studies or reviews. Studies or opinion pieces that involve patient, surgeon or trial characteristics, which influence the decision to participate in a trial, will be included. Study selection will be carried out independently by two authors with discrepancies resolved by consensus among three authors. Data will be charted using a standardised form, and results tabulated and narratively summarised with reference to the research questions of the review.Ethics and disseminationThe findings from this review will inform the design of a discrete choice experiment around willingness to participate in surgical trials, the outcomes of which can inform decision and cost-effectiveness models of sham surgery RCTs. The qualitative information from this review will also inform patient-centred outcomes research. The review will be published in a peer-reviewed journal.Trial registration numberCRD42019133296.

scholarly journals Identifying The Primary Outcome For A Randomised Controlled Trial In Rheumatoid Arthritis: The Role of A Discrete Choice Experiment

2017 ◽  
Vol 20 (9) ◽  
pp. A537
Author(s):  
E Stamuli ◽  
D Torgerson ◽  
M Northgraves ◽  
S Ronaldson ◽  
L Cherry
Keyword(s):  
Rheumatoid Arthritis ◽  
Randomised Controlled Trial ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Choice Experiment ◽  
Primary Outcome ◽  
Controlled Trial ◽  
Randomised Controlled

scholarly journals Identifying the primary outcome for a randomised controlled trial in rheumatoid arthritis: the role of a discrete choice experiment

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Eugena Stamuli ◽  
David Torgerson ◽  
Matthew Northgraves ◽  
Sarah Ronaldson ◽  
Lindsey Cherry
Keyword(s):  
Rheumatoid Arthritis ◽  
Randomised Controlled Trial ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Choice Experiment ◽  
Primary Outcome ◽  
Controlled Trial ◽  
Randomised Controlled

scholarly journals Evidence for the effects of viewing visual artworks on stress outcomes: a scoping review

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e043549
Author(s):  
Mikaela Law ◽  
Nikita Karulkar ◽  
Elizabeth Broadbent
Keyword(s):  
Heart Rate ◽  
Scoping Review ◽  
English Language ◽  
Data Extraction ◽  
Controlled Trial ◽  
Included Study ◽  
Individual Characteristics ◽  
Eligibility Criteria ◽  
Scoping Reviews ◽  
Randomised Controlled

ObjectiveTo review the existing evidence on the effects of viewing visual artworks on stress outcomes and outline any gaps in the research.DesignA scoping review was conducted based on the Joanna Briggs Institute methodology for scoping reviews and using the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. Two independent reviewers performed the screening and data extraction.Data sourcesMedline, Embase, APA PsycINFO, Cochrane CENTRAL, Scopus, Google Scholar, Google, ProQuest Theses and Dissertations Database, APA PsycExtra and Opengrey.eu were searched in May 2020.Eligibility criteriaStudies were included if they investigated the effects of viewing at least one visual artwork on at least one stress outcome measure. Studies involving active engagement with art, review papers or qualitative studies were excluded. There were no limits in terms of year of publication, contexts or population types; however, only studies published in the English language were considered.Data extraction and synthesisInformation extracted from manuscripts included: study methodologies, population and setting characteristics, details of the artwork interventions and key findings.Results14 primary studies were identified, with heterogeneous study designs, methodologies and artwork interventions. Many studies lacked important methodological details and only four studies were randomised controlled trials. 13 of the 14 studies on self-reported stress reported reductions after viewing artworks, and all of the four studies that examined systolic blood pressure reported reductions. Fewer studies examined heart rate, heart rate variability, cortisol, respiration or other physiological outcomes.ConclusionsThere is promising evidence for effects of viewing artwork on reducing stress. Moderating factors may include setting, individual characteristics, artwork content and viewing instructions. More robust research, using more standardised methods and randomised controlled trial designs, is needed.Registration detailsA protocol for this review is registered with the Open Science Framework (osf.io/gq5d8).

scholarly journals Financial incentives to discontinue long-term benzodiazepine use: a discrete choice experiment investigating patient preferences and willingness to participate

BMJ Open ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. e016229 ◽  
Author(s):  
Joachim Marti ◽  
Marcus Bachhuber ◽  
Jordyn Feingold ◽  
David Meads ◽  
Michael Richards ◽  
...  
Keyword(s):  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Financial Incentives ◽  
Choice Experiment ◽  
Economic Incentives ◽  
Willingness To Participate ◽  
Potential Cost ◽  
Substantial Impact ◽  
Benzodiazepine Use

ObjectivesInvestigate the acceptability of financial incentives for initiating a medically supervised benzodiazepine discontinuation programme among people with long-term benzodiazepine use and to identify programme features that influence willingness to participate.MethodsWe conducted a discrete choice experiment in which we presented a variety of incentive-based programs to a sample of older adults with long-term benzodiazepine use identified using the outpatient electronic health record of a university-owned health system. We studied four programme variables: incentive amount for initiating the programme, incentive amount for successful benzodiazepine discontinuation, lottery versus certain payment and whether partial payment was given for dose reduction. Respondents reported their willingness to participate in the programmes and additional information was collected on demographics, history of use and anxiety symptoms.ResultsThe overall response rate was 28.4%. Among the 126 respondents, all four programme variables influenced stated preferences. Respondents strongly preferred guaranteed cash-based incentives as opposed to a lottery, and the dollar amount of both the starting and conditional incentives had a substantial impact on choice. Willingness to participate increased with the amount of conditional incentive. Programme participation also varied by gender, duration of use and income.ConclusionsParticipation in an incentive-based benzodiazepine discontinuation programme might be relatively low, but is modifiable by programme variables including incentive amounts. These results will be helpful to inform the design of future trials of benzodiazepine discontinuation programmes. Further research is needed to assess the financial viability and potential cost-effectiveness of such economic incentives.

The essential ingredients of research supervision: A discrete-choice experiment.

2019 ◽  
Vol 111 (7) ◽  
pp. 1243-1260 ◽  
Author(s):  
Alex Roach ◽  
Bruce K. Christensen ◽  
Elizabeth Rieger
Keyword(s):  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Choice Experiment ◽  
Research Supervision

INDIVIDUALS' PREFERENCES FOR ESOPHAGEAL CANCER SCREENING STRATEGIES: A DISCRETE CHOICE EXPERIMENT

2019 ◽  
Author(s):  
Y Peters ◽  
E van Grinsven ◽  
M van de Haterd ◽  
D van Lankveld ◽  
J Verbakel ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Cancer Screening ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Choice Experiment ◽  
Screening Strategies

Preferences for antiviral therapy of chronic hepatitis C: a discrete choice experiment

2016 ◽  
Vol 18 (2) ◽  
pp. 155-165 ◽  
Author(s):  
Axel C. Mühlbacher ◽  
John F. P. Bridges ◽  
Susanne Bethge ◽  
Ch.-Markos Dintsios ◽  
Anja Schwalm ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Antiviral Therapy ◽  
Chronic Hepatitis C ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Choice Experiment
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