Attempting to explain heterogeneous HIV epidemics in sub-Saharan Africa: potential role of historical changes in risk behaviour and male circumcision

2011 ◽  
Vol 87 (7) ◽  
pp. 640-645 ◽  
Author(s):  
K. K. Orroth ◽  
R. G. White ◽  
E. E. Freeman ◽  
R. Bakker ◽  
A. Buve ◽  
...  
Keyword(s):  
Male Circumcision ◽  
Potential Role ◽  
Risk Behaviour ◽  
Sub Saharan Africa ◽  
Historical Changes ◽  
Changes In Risk ◽  
Sub Saharan

scholarly journals Serological Diagnostic Assays for HIV-Associated Tuberculosis in Sub-Saharan Africa?

2014 ◽  
Vol 21 (6) ◽  
pp. 787-790 ◽  
Author(s):  
Stephen D. Lawn
Keyword(s):  
Potential Role ◽  
Point Of Care ◽  
Antibody Responses ◽  
Sub Saharan Africa ◽  
Simple Point ◽  
Content Type ◽  
Diagnostic Assays ◽  
Hiv Coinfection ◽  
Sub Saharan

ABSTRACTIn this issue ofClinical and Vaccine Immunology, Siev and colleagues present an evaluation of antibody responses to four immunodominant proteins ofMycobacterium tuberculosisin patients with HIV-associated pulmonary tuberculosis (TB) in South Africa (M. Siev, D. Wilson, S. Kainth, V. O. Kasprowicz, C. M. Feintuch, E. Jenny-Avital, and J. J. Achkar, 21:791–798, 2014, doi:http://dx.doi.org/10.1128/CVI.00805-13). This commentary discusses the enormous need for simple point-of-care assays for tuberculosis (TB) diagnosis in patients with and without HIV coinfection in high-burden settings and considers the potential role of serological assays and the huge challenges inherent in developing and validating such assays.

scholarly journals Potential role of neglected and underutilized plant species in improving women’s empowerment and nutrition in areas of sub-Saharan Africa

2019 ◽  
Vol 77 (11) ◽  
pp. 817-828 ◽  
Author(s):  
Maria Vittoria Conti ◽  
Ausilia Campanaro ◽  
Paola Coccetti ◽  
Rachele De Giuseppe ◽  
Andrea Galimberti ◽  
...  
Keyword(s):  
Plant Species ◽  
Food Production ◽  
Potential Role ◽  
Nutrition Transition ◽  
Sub Saharan Africa ◽  
Diet Diversity ◽  
Nutrition Security ◽  
Local Agriculture ◽  
Sub Saharan

Abstract In the context of the nutrition transition, women in sub-Sahara Africa are a critical target group from a nutrition standpoint, and they experience significant discrimination in food production. Food-based, women-centered strategies are recommended to address nutrient gaps, and to educate and empower women. In this context, local natural resources, such as neglected and underutilized plant species (NUS), may contribute to adding nutritional value, enriching diet diversity, and ensuring nutrition security. The aim of the current narrative review is to investigate the nutritional status of the sub-Saharan African population and the potential role of local agriculture strategies in improving food production and diet diversity and in expanding income-generating activities for women. The nutritional properties of the most important regional NUS are also discussed.

scholarly journals The potential role of long-acting injectable cabotegravir–rilpivirine in the treatment of HIV in sub-Saharan Africa: a modelling analysis

2021 ◽  
Author(s):  
Andrew N Phillips ◽  
Loveleen Bansi-Matharu ◽  
Valentina Cambiano ◽  
Peter Ehrenkranz ◽  
Celicia Serenata ◽  
...  
Keyword(s):  
Potential Role ◽  
Sub Saharan Africa ◽  
Modelling Analysis ◽  
Sub Saharan ◽  
Long Acting

scholarly journals Recent advances in HIV-associated Kaposi sarcoma

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 970 ◽  
Author(s):  
Alessia Dalla Pria ◽  
David J. Pinato ◽  
Margherita Bracchi ◽  
Mark Bower
Keyword(s):  
Potential Role ◽  
Checkpoint Inhibitors ◽  
Kaposi Sarcoma ◽  
Epidemiological Data ◽  
Sub Saharan Africa ◽  
People Living With Hiv ◽  
Current Management ◽  
Sub Saharan ◽  
Living With Hiv

Kaposi sarcoma (KS) is a mesenchymal tumour caused by KS-associated herpesvirus and is an AIDS-defining illness. Despite a decline in incidence since the introduction of combination anti-retroviral therapy, KS remains the most common cancer in people living with HIV in sub-Saharan Africa, where it causes significant morbidity and mortality. This review reflects on recent epidemiological data as well as current management, unmet needs and future perspectives in the treatment of HIV-associated KS with particular emphasis on the potential role of immune checkpoint inhibitors.

scholarly journals The Role of Female Partners in the uptake of Voluntary Medical Male Circumcision in Sub-Saharan Africa: A Review

2019 ◽  
Vol 11 (7) ◽  
pp. 9
Author(s):  
Celenkosini Thembelenkosini Nxumalo ◽  
Gugu Gladness Mchunu
Keyword(s):  
Male Circumcision ◽  
Female Partner ◽  
Sub Saharan Africa ◽  
World Health ◽  
Voluntary Medical Male Circumcision ◽  
Medical Male Circumcision ◽  
Female Partners ◽  
Sub Saharan ◽  
Partner Involvement

BACKGROUND: Voluntary Medical Male Circumcision (VMMC) is a proven biological strategy for reducing heterosexual transmission of HIV/AIDS by up to 60%. Following recommendations from the World Health Organisation (WHO), Medical Circumcision (MC) was rolled out in South Africa. Several issues, among them being individual perceptual factors and female partner influence, have constituted as both obstacles and drivers to the uptake of VMMC. AIM: To explore and synthesize research conducted on the role of female partners in the uptake of VMMC. METHODS: Electronic searches were conducted in PUBMED, MEDLINE and CIHNAL, studies included in the review are those that explored the importance of female partner involvement in the uptake of VMMC. The review was limited to sub-Saharan Africa with a focus on peer reviewed articles written in English only. RESULTS: The review has revealed that considering the gender dimensions of circumcision, the possible utilisation of women as vehicles to drive the uptake of MC could be key to achieving the desired uptake. CONCLUSION: It is postulated that women play a key role in terms of promoting circumcision in order to facilitate a successful scale up of the service. Further research is therefore necessary so that the benefits of female partner involvement in VMMC may be achieved.

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