scholarly journals HIV drug resistance in sub-Saharan Africa: public health questions and the potential role of real-world data and mathematical modelling

2018 ◽  
Vol 4 ◽  
pp. 55-58 ◽  
Author(s):  
Reneé de Waal ◽  
Richard Lessells ◽  
Anthony Hauser ◽  
Roger Kouyos ◽  
Mary-Ann Davies ◽  
...  
Keyword(s):  
Public Health ◽  
Drug Resistance ◽  
Mathematical Modelling ◽  
Real World ◽  
Potential Role ◽  
Sub Saharan Africa ◽  
Real World Data ◽  
Hiv Drug Resistance ◽  
Sub Saharan

scholarly journals The Search for a Schistosomiasis Vaccine: Australia’s Contribution

Vaccines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 872
Author(s):  
Donald P. McManus
Keyword(s):  
Public Health ◽  
Drug Resistance ◽  
Sub Saharan Africa ◽  
Effective Vaccine ◽  
Neglected Tropical Disease ◽  
Vaccine Research ◽  
Health Measures ◽  
Leading Role ◽  
Invaluable Tool ◽  
Sub Saharan

Schistosomiasis, a neglected tropical disease caused by parasitic flatworms of the genus Schistosoma, results in considerable human morbidity in sub-Saharan Africa, in particular, but also parts of the Middle East, South America, and Southeast Asia. The anti-schistosome drug praziquantel is efficacious and safe against the adult parasites of all Schistosoma species infecting humans; however, it does not prevent reinfection and the development of drug resistance is a constant concern. The need to develop an effective vaccine is of great importance if the health of many in the developing world is to be improved. Indeed, vaccination, in combination with other public health measures, can provide an invaluable tool to achieve lasting control, leading to schistosomiasis elimination. Australia has played a leading role in schistosomiasis vaccine research over many years and this review presents an overview of some of the significant contributions made by Australian scientists in this important area.

scholarly journals Impact of HIV Drug Resistance on HIV/AIDS-Associated Mortality, New Infections, and Antiretroviral Therapy Program Costs in Sub–Saharan Africa

2017 ◽  
Vol 215 (9) ◽  
pp. 1362-1365 ◽  
Author(s):  
Andrew N Phillips ◽  
John Stover ◽  
Valentina Cambiano ◽  
Fumiyo Nakagawa ◽  
Michael R Jordan ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Sub Saharan Africa ◽  
Hiv Drug Resistance ◽  
Therapy Program ◽  
Sub Saharan ◽  
Program Costs ◽  
Hiv Aids

scholarly journals Serological Diagnostic Assays for HIV-Associated Tuberculosis in Sub-Saharan Africa?

2014 ◽  
Vol 21 (6) ◽  
pp. 787-790 ◽  
Author(s):  
Stephen D. Lawn
Keyword(s):  
Potential Role ◽  
Point Of Care ◽  
Antibody Responses ◽  
Sub Saharan Africa ◽  
Simple Point ◽  
Content Type ◽  
Diagnostic Assays ◽  
Hiv Coinfection ◽  
Sub Saharan

ABSTRACTIn this issue ofClinical and Vaccine Immunology, Siev and colleagues present an evaluation of antibody responses to four immunodominant proteins ofMycobacterium tuberculosisin patients with HIV-associated pulmonary tuberculosis (TB) in South Africa (M. Siev, D. Wilson, S. Kainth, V. O. Kasprowicz, C. M. Feintuch, E. Jenny-Avital, and J. J. Achkar, 21:791–798, 2014, doi:http://dx.doi.org/10.1128/CVI.00805-13). This commentary discusses the enormous need for simple point-of-care assays for tuberculosis (TB) diagnosis in patients with and without HIV coinfection in high-burden settings and considers the potential role of serological assays and the huge challenges inherent in developing and validating such assays.

scholarly journals HIV Drug Resistance in Sub-Saharan Africa – Implications for Testing and Treatment

HIV Testing ◽  
10.5772/30505 ◽  
2012 ◽  
Author(s):  
Kuan-Hsiang Gary ◽  
Helen Fryer ◽  
Dominique Goedhals ◽  
Cloete van ◽  
John Frater
Keyword(s):  
Drug Resistance ◽  
Sub Saharan Africa ◽  
Hiv Drug Resistance ◽  
Sub Saharan

scholarly journals Potential role of neglected and underutilized plant species in improving women’s empowerment and nutrition in areas of sub-Saharan Africa

2019 ◽  
Vol 77 (11) ◽  
pp. 817-828 ◽  
Author(s):  
Maria Vittoria Conti ◽  
Ausilia Campanaro ◽  
Paola Coccetti ◽  
Rachele De Giuseppe ◽  
Andrea Galimberti ◽  
...  
Keyword(s):  
Plant Species ◽  
Food Production ◽  
Potential Role ◽  
Nutrition Transition ◽  
Sub Saharan Africa ◽  
Diet Diversity ◽  
Nutrition Security ◽  
Local Agriculture ◽  
Sub Saharan

Abstract In the context of the nutrition transition, women in sub-Sahara Africa are a critical target group from a nutrition standpoint, and they experience significant discrimination in food production. Food-based, women-centered strategies are recommended to address nutrient gaps, and to educate and empower women. In this context, local natural resources, such as neglected and underutilized plant species (NUS), may contribute to adding nutritional value, enriching diet diversity, and ensuring nutrition security. The aim of the current narrative review is to investigate the nutritional status of the sub-Saharan African population and the potential role of local agriculture strategies in improving food production and diet diversity and in expanding income-generating activities for women. The nutritional properties of the most important regional NUS are also discussed.

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