Uroabdomen following rupture of a primary ureteral soft tissue sarcoma in a Labrador retriever

2020 ◽  
Vol 8 (3) ◽  
pp. e001199
Author(s):  
Beatrice Hertel ◽  
Henry L'Eplattenier

A seven-year-old, female neutered Labrador retriever presented for acute onset of lethargy and abdominal pain. Imaging showed the presence of an irregular mass in the left retroperitoneal space, extending from the caudal pole of the left kidney to the urinary bladder, and a moderate amount of peritoneal effusion. The excretory urography confirmed that the mass was originating from the ureter and the effusion was consistent with urine leakage. A left ureteronephrectomy was performed and histology revealed a primary soft tissue sarcoma of intermediate grade. This is the second description of ureteral soft tissue sarcoma and report of uroabdomen due to ureteral mass in veterinary literature.

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Terry M. Jacobs ◽  
Cathy E. Poehlmann ◽  
Matti Kiupel

This case report documents the clinical and pathological findings in a dog that rapidly developed a high-grade sarcoma at the site of multiple vaccinations and follows the response to surgery and adjunct treatment with toceranib. An 11-year-old female spayed Labrador Retriever presented with dorsocervical subcutaneous masses at the injection site three weeks after receiving DA2PP-Lepto, Rabies, and Bordetella vaccinations. A high-grade soft tissue sarcoma was diagnosed microscopically and immunohistochemistry revealed positive expression of VEGFr, PDGFr, SCF, and EGFR. Repeat surgical resections and targeted treatment with toceranib resulted in a stable remission for nearly two years.


2004 ◽  
Vol 7 (3) ◽  
pp. 209-212 ◽  
Author(s):  
Jacqueline C. Whittemore ◽  
Juliet R. Gionfriddo ◽  
Phillip F. Steyn ◽  
E. J. Ehrhart

Author(s):  
J. P. Brunschwig ◽  
R. M. McCombs ◽  
R. Mirkovic ◽  
M. Benyesh-Melnick

A new virus, established as a member of the herpesvirus group by electron microscopy, was isolated from spontaneously degenerating cell cultures derived from the kidneys and lungs of two normal tree shrews. The virus was found to replicate best in cells derived from the homologous species. The cells used were a tree shrew cell line, T-23, which was derived from a spontaneous soft tissue sarcoma. The virus did not multiply or did so poorly for a limited number of passages in human, monkey, rodent, rabbit or chick embryo cells. In the T-23 cells, the virus behaved as members of the subgroup B of herpesvirus, in that the virus remained primarily cell associated.


2020 ◽  
Author(s):  
S Weiß ◽  
A Korthaus ◽  
K-H Frosch ◽  
C Schlickewei ◽  
M Priemel

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