Sodium bicarbonate supplementation improved MAOD but is not correlated with 200- and 400-m running performances: a double-blind, crossover, and placebo-controlled study

2015 ◽  
Vol 40 (9) ◽  
pp. 931-937 ◽  
Author(s):  
Gabriel Motta Pinheiro Brisola ◽  
Willian Eiji Miyagi ◽  
Henrique Santos da Silva ◽  
Alessandro Moura Zagatto
Keyword(s):  
Oxygen Uptake ◽  
Sodium Bicarbonate ◽  
Maximal Oxygen Uptake ◽  
Lactate Concentration ◽  
Oxygen Deficit ◽  
Controlled Study ◽  
Performance Tests ◽  
Double Blind ◽  
Running Performance ◽  
Positive Effect

The aim of the study was to investigate the effects of acute supplementation of sodium bicarbonate (NaHCO3) on maximal accumulated oxygen deficit (MAOD) determined by a single supramaximal effort (MAODALT) in running and the correlation with 200- and 400-m running performances. Fifteen healthy men (age, 23 ± 4 years; maximal oxygen uptake, 50.6 ± 6.1 mL·kg−1·min−1) underwent a maximal incremental exercise test and 2 supramaximal efforts at 110% of the intensity associated with maximal oxygen uptake, which was carried out after ingesting either 0.3 g·kg−1 body weight NaHCO3 or a placebo (dextrose) and completing 200- and 400-m performance tests. The study design was double-blind, crossover, and placebo-controlled. Significant differences were found between the NaHCO3 and placebo conditions for MAODALT (p = 0.01) and the qualitative inference for substantial changes showed a very likely positive effect (98%). The lactic anaerobic contribution in the NaHCO3 ingestion condition was significantly higher (p < 0.01) and showed a very likely positive effect (99% chance), similar to that verified for peak blood lactate concentration (p < 0.01). No difference was found for time until exhaustion (p = 0.19) or alactic anaerobic contribution (p = 0.81). No significant correlations were observed between MAODALT and 200- and 400-m running performance tests. Therefore, we can conclude that both MAODALT and the anaerobic lactic metabolism are modified after acute NaHCO3 ingestion, but it is not correlated with running performance.

scholarly journals Acute administration of high doses of taurine does not substantially improve high-intensity running performance and the effect on maximal accumulated oxygen deficit is unclear

2016 ◽  
Vol 41 (5) ◽  
pp. 498-503 ◽  
Author(s):  
Fabio Milioni ◽  
Elvis de Souza Malta ◽  
Leandro George Spinola do Amaral Rocha ◽  
Camila Angélica Asahi Mesquita ◽  
Ellen Cristini de Freitas ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Exercise Intensity ◽  
Maximal Oxygen Uptake ◽  
High Intensity ◽  
Treadmill Running ◽  
Oxygen Deficit ◽  
Time To Exhaustion ◽  
Acute Administration ◽  
Running Performance ◽  
Accumulated Oxygen Deficit

The aim of the present study was to investigate the effects of acute administration of taurine overload on time to exhaustion (TTE) of high-intensity running performance and alternative maximal accumulated oxygen deficit (MAODALT). The study design was a randomized, placebo-controlled, crossover design. Seventeen healthy male volunteers (age: 25 ± 6 years; maximal oxygen uptake: 50.5 ± 7.6 mL·kg−1·min−1) performed an incremental treadmill-running test until voluntary exhaustion to determine maximal oxygen uptake and exercise intensity at maximal oxygen uptake. Subsequently, participants completed randomly 2 bouts of supramaximal treadmill-running at 110% exercise intensity at maximal oxygen uptake until exhaustion (placebo (6 g dextrose) or taurine (6 g) supplementation), separated by 1 week. MAODALT was determined using a single supramaximal effort by summating the contribution of the phosphagen and glycolytic pathways. When comparing the results of the supramaximal trials (i.e., placebo and taurine conditions) no differences were observed for high-intensity running TTE (237.70 ± 66.00 and 277.30 ± 40.64 s; p = 0.44) and MAODALT (55.77 ± 8.22 and 55.06 ± 7.89 mL·kg−1; p = 0.61), which seem to indicate trivial and unclear differences using the magnitude-based inferences approach, respectively. In conclusion, acute 6 g taurine supplementation before exercise did not substantially improve high-intensity running performance and showed an unclear effect on MAODALT.

The Effects of Caffeine on the Maximal Accumulated Oxygen Deficit and Short-Term Running Performance

1998 ◽  
Vol 8 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Michael Doherty
Keyword(s):  
Lactate Concentration ◽  
Blood Lactate Concentration ◽  
Oxygen Deficit ◽  
Preliminary Assessment ◽  
Short Term ◽  
Placebo Condition ◽  
Double Blind ◽  
Caffeine Ingestion ◽  
Running Performance ◽  
Accumulated Oxygen Deficit

The purpose of this study was to evaluate the effect of acute caffeine ingestion on the maximal accumulated oxygen deficit (MAOD) and short-term running performance. Nine well-trained males performed a preliminary assessment and. at least 4 days later, a supramaximal run to exhaustion. Their VO2max values were determined, and the MAOD test at an exercise intensity equivalent to 125% VO2max was performed. Caffeine (5 mg ⋅ kg−1) or placebo was administered 1 hr prior to the MAOD in a double-blind, randomized cross-over study. In comparison to the placebo condition, subjects in the caffeine condition developed a significantly greater MAOD and increased their run lime to exhaustion. However, posl-MAOD blood lactate concentration ([HLa]) was not different between trials for caffeine and placebo. Caffeine ingestion can be an effective ergogenic aid for short-term, supramaximal running performance and can increase MAOD. However, these results do not appear to be related to an increased [HLa).

scholarly journals Effect of paprika xanthophyll supplementation on oxygen uptake in athletes: a randomized, double-blind, placebo-controlled study

2018 ◽  
Vol 7 (4) ◽  
pp. 247-252
Author(s):  
Takashi Ichihara ◽  
Azusa Nishino ◽  
Takeshi Takaha ◽  
Takashi Kuriki ◽  
Hideko Nihei ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Assessment of two methods to determine the relative contributions of the aerobic and anaerobic energy systems in racehorses

2019 ◽  
Vol 126 (5) ◽  
pp. 1390-1398 ◽  
Author(s):  
Stephanie L. Bond ◽  
Persephone Greco-Otto ◽  
Raymond Sides ◽  
Grace P. S. Kwong ◽  
Renaud Léguillette ◽  
...  
Keyword(s):  
Exercise Intensity ◽  
Fixed Effects ◽  
Lactate Concentration ◽  
Relative Energy ◽  
Oxygen Deficit ◽  
Controlled Study ◽  
Supramaximal Exercise ◽  
Thoroughbred Racehorses ◽  
Anaerobic Energy ◽  
Aerobic And Anaerobic

A prospective, randomized, controlled study was designed to determine relative aerobic and anaerobic (lactic and alactic) contributions at supramaximal exercise intensities using two different methods. Thoroughbred racehorses ( n = 5) performed a maximal rate of oxygen consumption (V̇o2max) test and three supramaximal treadmill runs (105, 115, and 125% V̇o2max). Blood lactate concentration (BL) was measured at rest, every 15 s during runs, and 2, 5, 10, 20, 30, 40, 50, and 60 min postexercise. In method 1, oxygen demand was calculated for each supramaximal intensity based on the V̇o2max test, and relative aerobic and anaerobic contributions were calculated from measured V̇o2 and the accumulated oxygen deficit. In method 2, aerobic contribution was calculated using the trapezoidal method to determine V̇o2 during exercise. A monoexponential model was fitted to the postexercise V̇o2 curve. Alactic contribution was calculated using the coefficients of this model. Lactate anaerobic contribution was calculated by multiplying the peak to resting change in BL by 3. Linear mixed-effects models were used to examine the effects of exercise intensity and method (as fixed effects) on measured outcomes ( P ≤ 0.05). Relative aerobic and anaerobic contributions were not different between methods ( P = 0.20). Horses’ mean contributions were 81.4, 77.6, and 72.5% (aerobic), and 18.5, 22.3, and 27.4% (anaerobic) at 105, 115, and 125% V̇o2max, respectively. Individual alactic anaerobic energy was not different between supramaximal exercise intensities ( P = 0.43) and was negligible, contributing a mean of 0.11% of the total energy. Relative energy contributions can be calculated using measured V̇o2 and BL in situations where the exercise intensity is unknown. Understanding relative metabolic demands could help develop tailored training programs. NEW & NOTEWORTHY Relative energy contributions of horses can be calculated using measured V̇o2 and BL in situations where the exercise intensity is unknown. Horses’ mean contributions were 81.4, 77.6, and 72.5% (aerobic), and 18.5, 22.3, and 27.4% (anaerobic) at 105, 115, and 125% of V̇o2max, respectively. Individual alactic capacity was unaltered between supramaximal exercise intensities and accounted for a mean contribution of 0.11% of energy use.

scholarly journals The Effect of Orally Dosed Levagen+™ (palmitoylethanolamide) on Exercise Recovery in Healthy Males—A Double-Blind, Randomized, Placebo-Controlled Study

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 596 ◽  
Author(s):  
Alistair Mallard ◽  
David Briskey ◽  
Andrew Richards ◽  
Dean Mills ◽  
Amanda Rao
Keyword(s):  
Muscle Damage ◽  
Blood Lactate ◽  
Muscle Soreness ◽  
Lactate Concentration ◽  
Blood Lactate Concentration ◽  
Controlled Study ◽  
Thigh Circumference ◽  
Double Blind ◽  
Post Exercise ◽  
Leg Press

The aim of this study was to evaluate the effect of palmitoylethanolamide (PEA), a cannabimimetic compound and lipid messenger, on recovery from muscle damaging exercise. Twenty-eight healthy young male participants attended the laboratory four times on subsequent days. In the first visit, baseline characteristics were recorded before participants were randomized to consume either liquid PEA (167.5 mg Levagen+ with 832.5 mg maltodextrin) or a matched placebo (1 g maltodextrin) drink. Leg press exercise consisted of four sets at 80% of one repetition maximum followed by a performance set. Muscle soreness, thigh circumference, blood lactate concentration, biomarkers of muscle damage and inflammation, and transcription factor pathways were measured pre- and immediately post-exercise and again at 1, 2, 3, 24, 48, and 72 h post-exercise. The leg press exercise increased (p < 0.05) blood lactate concentration and induced muscle damage as evidenced by increased muscle soreness, thigh circumference, biomarkers of muscle damage, and concentrations of tumor necrosis factor-α. PEA reduced (p < 0.05) myoglobin and blood lactate concentrations and increased protein kinase B phosphorylation following exercise. Taken together, these results indicate PEA supplementation may aid in muscle recovery from repeat bouts of exercise performed within a short duration by reducing myoglobin and lactate concentration.

Caffeine Improved Time to Exhaustion But Did Not Change Alternative Maximal Accumulated Oxygen Deficit Estimated During a Single Supramaximal Running Bout

2016 ◽  
Vol 26 (6) ◽  
pp. 549-557 ◽  
Author(s):  
Rodrigo De Araujo Bonetti De Poli ◽  
Willian Eiji Miyagi ◽  
Fabio Yuzo Nakamura ◽  
Alessandro Moura Zagatto
Keyword(s):  
Anaerobic Capacity ◽  
Oxygen Deficit ◽  
Time To Exhaustion ◽  
Placebo Condition ◽  
Double Blind ◽  
Caffeine Ingestion ◽  
Total Body Mass ◽  
Accumulated Oxygen Deficit ◽  
Negative Effect ◽  
Positive Effect

The aim of the current study was to investigate the effects of acute caffeine supplementation on anaerobic capacity determined by the alternative maximal accumulated oxygen deficit (MAODALT) in running effort. Eighteen recreational male runners [29 ± 7years; total body mass 72.1 ± 5.8 kg; height 176.0 ± 5.4cm; maximal oxygen uptake (VO2max) 55.8 ± 4.2 ml·kg-1 ·min-1] underwent a graded exercise test. Caffeine (6 mg·kg-1) or a placebo were administered 1 hr before the supramaximal effort at 115% of the intensity associated with VO2max in a double-blind, randomized cross-over study, for MAODALT assessment. The time to exhaustion under caffeine condition (130.2 ± 24.5s) was 11.3% higher (p = .01) than placebo condition (118.8 ± 24.9 s) and the qualitative inference for substantial changes showed a very likely positive effect (93%). The net participation of the oxidative phosphorylation pathway was significantly higher in the caffeine condition (p = .02) and showed a likely positive effect (90%) of 15.3% with caffeine supplementation. The time constant of abrupt decay of excess postexercise oxygen consumption (τ1) was significantly different between caffeine and placebo conditions (p = .03) and showed a likely negative effect (90%), decreasing -8.0% with caffeine supplementation. The oxygen equivalents estimated from the glycolytic and phosphagen metabolic pathways showed a possibly positive effect (68%) and possibly negative effect (78%) in the qualitative inference with caffeine ingestion, respectively. However, the MAODALT did not differ under the caffeine or placebo conditions (p = .68). Therefore, we can conclude that acute caffeine ingestion does not modify the MAODALT, reinforcing the robustness of this method. However, caffeine ingestion can alter the glycolytic and phosphagen metabolic pathway contributions to MAODALT.

Does Sodium-Bicarbonate Ingestion Improve Simulated Judo Performance?

2007 ◽  
Vol 17 (2) ◽  
pp. 206-217 ◽  
Author(s):  
Guilherme Giannini Artioli ◽  
Bruno Gualano ◽  
Desiré Ferreira Coelho ◽  
Fabiana Braga Benatti ◽  
Alessandra Whyte Gailey ◽  
...  
Keyword(s):  
Sodium Bicarbonate ◽  
Peak Power ◽  
Perceived Exertion ◽  
Lactate Concentration ◽  
Blood Lactate Concentration ◽  
Crossover Design ◽  
Ratings Of Perceived Exertion ◽  
Mean Power ◽  
Double Blind ◽  
Improved Performance

The aim of the present study was to investigate whether pre exercise sodium-bicarbonate ingestion improves judo-related performance. The study used 2 different protocols to evaluate performance: 3 bouts of a specific judo test (n = 9) and 4 bouts of the Wingate test for upper limbs (n = 14). In both protocols athletes ingested 0.3 g/kg of sodium bicarbonate or placebo 2 h before the tests. Blood samples were collected to determine lactate level, and levels of perceived exertion were measured throughout the trials. The study used a double-blind, counterbalanced, crossover design. Ingestion of sodium bicarbonate improved performance in Bouts 2 and 3 of Protocol 1 (P < 0.05), mean power in Bouts 3 and 4 of Protocol 2 (P < 0.05), and peak power in Bout 4 of Protocol 2 (P < 0.05). Ingestion of bicarbonate increased lactate concentration in Protocol 1 (P < 0.05) but not in Protocol 2. Ratings of perceived exertion did not differ between treatments. In conclusion, sodium bicarbonate improves judo-related performance and increases blood lactate concentration but has no effect on perceived exertion.

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