Specific interactions between amino acid side chains — a partial molar volume study

1988 ◽  
Vol 66 (3) ◽  
pp. 487-490 ◽  
Author(s):  
Mandapati V. R. Rao ◽  
Mahalakshmi Atreyi ◽  
Moganty R. Rajeswari
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Aspartic Acid ◽  
Partial Molar Volumes ◽  
Ionic Species ◽  
Side Chains ◽  
Specific Interactions ◽  
Molar Volumes ◽  
Amino Acid Side Chains ◽  
Experimental Values

Partial molar volumes of the following mixtures, [Formula: see text](mix) were determined in water at 20 °C: (1) glutamic acid: glycine; (2) arginine:glycine; (3) arginine:glutamic acid; (4) arginine: aspartic acid; (5) lysine:glutamic acid, and (6) lysine: aspartic acid. Partial molar volumes of the mixtures calculated using [Formula: see text] of various ionic species of the amino acids agreed with the experimental values for systems 1 and 2, but were less than the experimental values for systems 3 to 6. The positive deviations, [Formula: see text] (mix), of the experimental values from the calculated values are discussed in terms of "specific interactions" between ionogenic side chains. The extent of interaction is greater in systems containing aspartic acid and/or arginine.

Partial molar volumes of .alpha.-amino acids with ionogenic side chains in water

1984 ◽  
Vol 88 (14) ◽  
pp. 3129-3131 ◽  
Author(s):  
M. V. R. Rao ◽  
M. Atreyi ◽  
M. R. Rajeswari
Keyword(s):  
Amino Acids ◽  
Partial Molar Volumes ◽  
Side Chains ◽  
Molar Volumes

ChemInform Abstract: Highly Diastereoselective Preparation of anti-α,β-Dialkyl β-Amino Acids Containing Natural α-Amino Acid Side Chains.

ChemInform ◽  
2008 ◽  
Vol 39 (11) ◽  
Author(s):  
Stefania Capone ◽  
Silvana Pedatella ◽  
Annalisa Guaragna ◽  
Mauro De Nisco ◽  
Giovanni Palumbo
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Side Chains ◽  
Amino Acid Side Chains

scholarly journals Proposal of the Annotation of Phosphorylated Amino Acids and Peptides Using Biological and Chemical Codes

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 712
Author(s):  
Piotr Minkiewicz ◽  
Małgorzata Darewicz ◽  
Anna Iwaniak ◽  
Marta Turło
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Functional Properties ◽  
Side Chains ◽  
Amino Acid Side Chains ◽  
The Future ◽  
Chemical Code ◽  
Internet Databases

Phosphorylation represents one of the most important modifications of amino acids, peptides, and proteins. By modifying the latter, it is useful in improving the functional properties of foods. Although all these substances are broadly annotated in internet databases, there is no unified code for their annotation. The present publication aims to describe a simple code for the annotation of phosphopeptide sequences. The proposed code describes the location of phosphate residues in amino acid side chains (including new rules of atom numbering in amino acids) and the diversity of phosphate residues (e.g., di- and triphosphate residues and phosphate amidation). This article also includes translating the proposed biological code into SMILES, being the most commonly used chemical code. Finally, it discusses possible errors associated with applying the proposed code and in the resulting SMILES representations of phosphopeptides. The proposed code can be extended to describe other modifications in the future.

A study of the reactivity of S(VI)–F containing warheads with nucleophilic amino-acid side chains under physiological conditions

2017 ◽  
Vol 15 (45) ◽  
pp. 9685-9695 ◽  
Author(s):  
H. Mukherjee ◽  
J. Debreczeni ◽  
J. Breed ◽  
S. Tentarelli ◽  
B. Aquila ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Side Chains ◽  
Physiological Conditions ◽  
Amino Acid Side Chains

Profiling the reactivity and stability of SVI–F warheads towards nucleophilic amino acids for the development of biochemical probe compounds.

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